Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Helga van Rennes"'
Autor:
Sirin Cansiz-Arda, Oskar Engberg, Madis Lõhmus, Helen M. Cooper, Johannes N. Spelbrink, Ian Holt, Helga van Rennes, Joachim M. Gerhold, Alberto Sanz, Aurelio Reyes
Publikováno v:
Scientific Reports. 5
The helicase Twinkle is indispensable for mtDNA replication in nucleoids. Previously, we showed that Twinkle is tightly membrane-associated even in the absence of mtDNA, which suggests that Twinkle is part of a membrane-attached replication platform.
Autor:
Ian J Holt, Sirin Cansiz-Arda, Helga van Rennes, Johannes N. Spelbrink, Aurelio Reyes, Madis Lõhmus, Helen M. Cooper, Oskar Engberg, Alberto Sanz, Joachim M. Gerhold
Publikováno v:
Scientific Reports, 5
Scientific Reports
Scientific Reports
The helicase Twinkle is indispensable for mtDNA replication in nucleoids. Previously, we showed that Twinkle is tightly membrane-associated even in the absence of mtDNA, which suggests that Twinkle is part of a membrane-attached replication platform.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258df1674c836eb7fa5e1ab15514af95
https://hdl.handle.net/2066/152311
https://hdl.handle.net/2066/152311
Autor:
Merlijn Bazuine, J. Antonie Maassen, Remko R. Bosch, Cees J. Tack, Ad R. M. M. Hermus, Paul N. Span, André J. Olthaar, Helga van Rennes, Peter H.G.M. Willems, C.G.J. Sweep
Publikováno v:
Biochemical journal, 384(Part 2), 349-355. Portland Press Ltd.
Biochemical Journal, 384, 349-55
Biochemical Journal, 384, Pt 2, pp. 349-55
Biochemical Journal, 384, 349-55
Biochemical Journal, 384, Pt 2, pp. 349-55
Contains fulltext : 57749.pdf (Publisher’s version ) (Open Access) Members of the PKC (protein kinase C) superfamily play key regulatory roles in glucose transport. How the different PKC isotypes are involved in the regulation of glucose transport
Publikováno v:
British Journal of Dermatology. 108:647-652
SUMMARY Keratotome slices were cut across the margins of rapidly-spreading psoriatic plaques. Each slice was divided into eight sections and in each section we measured the percentage cells in S phase and the levels of glucose-6-phosphate dehydrogena
Autor:
J.P.M. Geerdink, M.R. Franzen, J.M. Gommans, Mieke Bergers, P.E.J. van Erp, P.D. Mier, P.H.M. de Mulder, Helga van Rennes
Publikováno v:
Journal of Investigative Dermatology. 82:122-125
We report an investigation of peripheral blood monocytes from untreated patients with mild, quiescent psoriasis. Possible metabolic changes were monitored by the determination of 3 enzymes representing different pathways of glucose metabolism and 2 l
Autor:
D. J. Theo Wagener, Benjamin Winograd, Leon A. G. M. van den Broek, Harry C. J. Ottenheijm, Eppo van der Kleijn, Tom B. Vree, Zbigniew Zylicz, Helga van Rennes, Urbanus van Haelst, J. M. C. Wessels, Pilar Fernandez del Moral
Publikováno v:
Cancer Chemotherapy and Pharmacology. 20:115-124
Sparsomycin is a cytotoxic drug exhibiting a broad spectrum of in vitro activity against murine tumors and many tumor cell lines. It also appears to be a potent stimulator of the antitumor activity of cisplatin against L1210 leukemia in vivo. However
Publikováno v:
Journal of Investigative Dermatology. 78(4):267-269
A fluorometric microassay is described for sialidase using the natural substrate sialyllactose. This technique has been used to characterize and quantify cutaneous sialidase. The enzyme was found exclusively in the particulate fraction of skin homoge
Publikováno v:
The British journal of dermatology. 109(3)
SUMMARY Test sites on healthy controls and on the clinically uninvolved skin of psoriatic patients were stripped with tape, and eight variables were quantified at intervals during the subsequent healing process. In the control groups, the stratum cor
Autor:
Harry C. J. Ottenheijm, Zbigniew Zylicz, Helga van Rennes, Leon A. G. M. van den Broek, D. J. Theo Wagener, Peter Lelieveld, Eppo van der Kleijn
Publikováno v:
Investigational new drugs. 6(4)
Sparsomycin (Sm) is a known inhibitor of ribosomal protein synthesis with an attractive anticancer potential. Recently, several analogues of Sm which are more active than the parent drug were selected for further study on the basis of in vitro invest
Autor:
Harry C. J. Ottenheijm, Zbigniew Zylicz, Helga van Rennes, Willem J. de Grip, Leon A. G. M. van den Broek, Eppo van der Kleijn, J. M. C. Wessels, D. J. Theo Wagener
Publikováno v:
Cancer letters. 32(1)
The influence of protein synthesis inhibition by sparsomycin (Sm) on in vivo cisplatin activity has been studied on BALBc X DBA2: F1 mice bearing L1210 leukemia i.p. Sm alone at the dose range from 0.5 to 3.0 mg/kg did not significantly improve anima