Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Helga Remkes"'
Autor:
Anne Laser, S Neubauer, Martin J. Lohse, Michael Horn, Helga Remkes, Georg Ertl, Monika Frank, Kai Hu
Creatine kinase (CK) plays a crucial role in cardiac energy transduction. During chronic cardiac stress conditions leading to hypertrophy and/or heart failure, the profile of CK isoenzyme activities changes towards a fetal pattern with increases of B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9546aaa9f47128e09e4c2ab7ca362fca
https://doi.org/10.1006/jmcc.1998.0645
https://doi.org/10.1006/jmcc.1998.0645
Autor:
Tobias J. Schmidt, Clemens Schmidt, Helga Remkes, Michael Horn, Georg Ertl, Kerstin D. Hoffmann, S Neubauer, Kai Hu, Klaus Schnackerz
Oral feeding with the creatine analogue beta-guanidinopropionate (beta-GP) reduces myocardial phosphocreatine and creatine concentrations by about 80%in vitro, this is accompanied by reduced contractile performance. We hypothesized, thus, that beta-G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9254e20775bccf35697f8bac3b542e6f
https://ora.ox.ac.uk/objects/uuid:83dea31c-3607-4b1e-918c-8a7c64d51133
https://ora.ox.ac.uk/objects/uuid:83dea31c-3607-4b1e-918c-8a7c64d51133
OBJECTIVE: In heart failure, cardiac energy metabolism is compromised. The failing myocardium is characterized by reduced contents of both phosphorylated (phosphocreatine) and non-phosphorylated (free) creatine content as well as decreased energy res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a387f981b33d5811280727a1f34ae3
https://doi.org/10.1016/s0008-6363(99)00075-9
https://doi.org/10.1016/s0008-6363(99)00075-9
Autor:
Stefan Frantz, Michael Horn, Klaus D. Schnackerz, Helga Remkes, Stefan Neubauer, Bert Urban, Anne Laser, Andreas Mettenleiter
Publikováno v:
Journal of Molecular and Cellular Cardiology. 30:277-284
Little is known about the regulation of total creatine concentration in heart, skeletal muscle, brain, liver and kidney in response to increased dietary creatine intake. The phosphorylated fraction of intracellular creatine (phosphocreatine) remain r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1893604aac3830b2b0db3d2baaa92e
https://doi.org/10.1006/jmcc.1997.0590
https://doi.org/10.1006/jmcc.1997.0590
Publikováno v:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 3(3)
PURPOSE: Angiotensin-converting enzyme (ACE) inhibitors show beneficial long-term hemodynamic effects in chronically infarcted hearts. The purpose of this study was to test whether prevention of the deterioration of mechanical function by ACE inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175468216cee59ab525a2b6a0347ea08
https://pubmed.ncbi.nlm.nih.gov/11816618
https://pubmed.ncbi.nlm.nih.gov/11816618
Publikováno v:
Circulation. 104(15)
Background The failing myocardium is characterized by reductions of phosphocreatine (PCr) and free creatine content and by decreases of energy reserve via creatine kinase (CK), ie, CK reaction velocity (Flux CK ). It has remained unclear whether thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991e196c201146f5d8ac16d9a7dfe30a
http://ora.ox.ac.uk/objects/uuid:156e5ce5-d65f-4ab8-a50a-5ea28478541b
http://ora.ox.ac.uk/objects/uuid:156e5ce5-d65f-4ab8-a50a-5ea28478541b
Autor:
M. Meininger, Helga Remkes, Michael Horn, Claudia Weidensteiner, S Neubauer, Karin Przyklenk, Markus von Kienlin, Mark C.H. De Groot, Charlotte Dienesch, Heike Scheffer
Publikováno v:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 45(5)
MRI of total sodium (Na) content may allow assessment of myocardial viability, but information on Na content in normal myocardium, necrotic/scar tissue, and stunned or hibernating myocardium is lacking. Thus, the aims of the study were to: 1) quantif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045b234c6f9524b4084756aa3f09430a
http://ora.ox.ac.uk/objects/uuid:8d38fdf2-ca72-4773-acdb-f5e3e70f9abc
http://ora.ox.ac.uk/objects/uuid:8d38fdf2-ca72-4773-acdb-f5e3e70f9abc
Autor:
Nicole Büchler, Stefan Hammerschmidt, S Neubauer, Michael Bell, Hans Wahn, Helga Remkes, Martin J. Lohse
Publikováno v:
Biochimica et biophysica acta. 1502(3)
Creatine kinase (CK) plays a crucial role in myocardial energy metabolism. Alterations in CK gene expression are found in hypertrophied and failing heart, but the mechanisms behind these changes are unclear. This study tests the hypothesis that incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475abdc7344def18c7728df7f0dfd879
http://ora.ox.ac.uk/objects/uuid:493ae95b-905b-40c7-922e-00f1c50fca89
http://ora.ox.ac.uk/objects/uuid:493ae95b-905b-40c7-922e-00f1c50fca89
Autor:
S. Hugel, M. J. M. De Groot, Michael Horn, Helga Remkes, Kai Hu, Charlotte Dienesch, G. Ertl, S Neubauer
Publikováno v:
Scopus-Elsevier
Chronic treatment with β-receptor blockers or angiotensin-converting enzyme (ACE) inhibitors in heart failure can reduce mortality and improve left ventricular function, but the mechanisms involved in their beneficial action remain to be fully defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9779c32aa8cad83ce440b7735b0cf4
http://ora.ox.ac.uk/objects/uuid:5672853d-8d96-4a3a-83db-0b86f59a2641
http://ora.ox.ac.uk/objects/uuid:5672853d-8d96-4a3a-83db-0b86f59a2641
Publikováno v:
American Journal of Hypertension. 12:184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e7f03457dec375701a2ba92433da93
https://doi.org/10.1016/s0895-7061(99)80667-0
https://doi.org/10.1016/s0895-7061(99)80667-0