Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Helga K. Einarsdottir"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Objectives: It has recently been shown that individuals with selective IgA deficiency (sIgAD) have defective B cell responses both to T cell dependent and independent mimicking stimulations. The complex intracellular signaling pathways from different
Externí odkaz:
https://doaj.org/article/c8f23d9e8f3745f5ab651e1a228446e7
Autor:
Andri L. Lemarquis, Helga K. Einarsdottir, Rakel N. Kristjansdottir, Ingileif Jonsdottir, Bjorn R. Ludviksson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Selective IgA deficiency (IgAD) is the most common primary antibody deficiency in the western world with affected individuals suffering from an increased burden of autoimmunity, atopic diseases and infections. It has been shown that IgAD B cells can
Externí odkaz:
https://doaj.org/article/ffcb61de06884d969f5f740b2b58e5d4
Autor:
Sveinn Vidar Gudmundsson, Bjorn R. Ludviksson, Helga K. Einarsdottir, Bjorn Gudbjornsson, Una Bjarnadottir, Dagrun Jonasdottir, Elínborg Stefánsdóttir, Einar Axel Helgason
Publikováno v:
Scandinavian journal of immunologyREFERENCES. 95(1)
Rheumatoid arthritis (RA) is a chronic multisystem disease with a complex immunopathology. Its inflammatory state is dominated by pro-inflammatory cytokines such as TNFα and activated Th1/Th17. Only proportion of patients achieve clinical remission
Autor:
Bjorn R. Ludviksson, Jón Ólafsson, Jenna Huld Eysteinsdóttir, Jona Freysdottir, Helga K. Einarsdottir, Bardur Sigurgeirsson, Bjarni A. Agnarsson, Hildur Sigurgrimsdottir, Eva Osp Bjornsdottir
Publikováno v:
Scandinavian journal of immunologyREFERENCES. 94(6)
Psoriasis is an autoimmune disease driven by a Th17 response linked to the antimicrobial peptide (AMP) LL-37 that has been connected to the induction and chronicity of psoriasis. We show that keratinocytes secrete various immune biomarkers with a dir
Autor:
Hildur Sigurgrimsdottir, Bárður Sigurgeirsson, Björn Rúnar Lúðvíksson, Jona Freysdottir, Bjarni A. Agnarsson, Helga K. Einarsdottir, Jón Ólafsson, Jenna Huld Eysteinsdóttir
Publikováno v:
Journal of dermatological science. 96(2)
Publikováno v:
Immunological Reviews. 268:253-268
The neonatal Fc receptor, FcRn, is best known for its role in transporting IgG in various tissues, providing newborns with humoral immunity, and for prolonging the half-life of IgG. Recent findings implicate the involvement of FcRn in a far wider ran
Publikováno v:
Immunology letters, 160(2), 139-144. Elsevier
IgG-antibodies are potent and versatile mediators of host protection. They elicit their biological effects through specific interaction of the Fc-part with complement, specific cellular receptors, or both. Several factors should be taken into conside
Autor:
Dave Jackson, C. Ellen van der Schoot, Theo Rispens, Iwan Kustiawan, Masja de Haas, Mette Kjaer Killie, Dennis Blank, Helga K. Einarsdottir, Terje E. Michaelsen, Belinda Kumpel, Carolien A. M. Koeleman, Leendert Porcelijn, Bjørn Skogen, Anne Vestrheim, Remco Visser, André M. Deelder, Rick Kapur, Manfred Wuhrer, Gestur Vidarsson
Publikováno v:
Blood; Vol 123
Blood, 123(4), 471-480. American Society of Hematology
Blood, 123(4), 471-480
Blood, 123(4), 471-480. American Society of Hematology
Blood, 123(4), 471-480
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. Immunoglobulin G (IgG) formed during pregnanc
Autor:
Sicco A. Scherjon, Yanli Ji, Helga K. Einarsdottir, Guangping Luo, Gestur Vidarsson, Chunyan Mo, Remco Visser, C. Ellen van der Schoot
Publikováno v:
Transfusion. 54:665-671
Background The neonatal receptor (FcRn) extends the half-life of human immunoglobulin (Ig)G and transports it across the placenta, providing the newborn with humoral immunity. Of the four subclasses, IgG3 stands out with strong effector functions, sh
Autor:
Ellen van der Schoot, Helga K. Einarsdottir, Debby Kruijsen, Frank E. J. Coenjaerts, Grada M. van Bleek, Gestur Vidarsson, Marcel A. Schijf
Publikováno v:
Journal of virology, 87(13), 7550-7557. American Society for Microbiology
Infants are protected from a severe respiratory syncytial virus (RSV) infection in the first months of life by maternal antibodies or by prophylactically administered neutralizing antibodies. Efforts are under way to produce RSV-specific antibodies w