Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Helga Engi"'
Autor:
HELGA, ENGI, ERIKA, TÓTH
Publikováno v:
Magyar Onkologia; 2023, Vol. 67 Issue 2, p125-130, 6p
Autor:
Péter Molnár, Judit Hohmann, Helga Engi, Krystyna Michalak, József Deli, Olga Wesołowska, Joseph Molnár, Qi Wang
Publikováno v:
Current Topics in Medicinal Chemistry. 10:1757-1768
The multidrug resistance (MDR) proteins that belong to the ATP-binding cassette superfamily such as P-glycoprotein (P-gp) and MRP1, are present in a majority of human tumors and constitute an important cause of therapeutic failure. Selective inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3633f534dcde6a38f1adca00996d98e
https://doi.org/10.2174/156802610792928103
https://doi.org/10.2174/156802610792928103
Autor:
Josef Makovitzky, Ufuk Gündüz, Meltem Demirel Kars, Willy J. Peumans, Joseph Molnár, Helga Engi, Nóra Gyémánt, Els J.M. Van Damme, Udo Schumacher, Péter Molnár
Publikováno v:
Scopus-Elsevier
Phospho-glycoprotein (P-gp) is a polytopic plasma membrane protein whose overexpression causes multidrug resistance (MDR) responsible for the failure of cancer chemotherapy. P-gp 170 is a member of the ATP-binding cassette (ABC) transporter superfami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e076d70ffc64a54afa3b72dd4effb07f
https://doi.org/10.1016/j.acthis.2008.11.010
https://doi.org/10.1016/j.acthis.2008.11.010
Autor:
Helga Engi
Publikováno v:
Orvosi Hetilap. 150:607-614
A daganatos megbetegedések elleni küzdelem hatásosságában a multidrog-rezisztencia kérdésének megoldása fontos szerepet játszik. Növekvő igény mutatkozik olyan új vegyületek kifejlesztésére, amelyek képesek gátolni a különböző
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774cb96ea8f8179f436f7fe7f7139fcb
https://doi.org/10.1556/oh.2009.28358
https://doi.org/10.1556/oh.2009.28358
Autor:
Helga Engi
Publikováno v:
Hungarian Medical Journal. 2:279-291
The development of pharmacological agents able to counteract the mechanisms of multidrug resistance (MDR) in oncology has remained a major goal for the past ten years. Several mechanisms are thought to be involved in drug resistance, including those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cdbc36c998e6a0c940ca50dc2ca7cab
https://doi.org/10.1556/hmj.2.2008.2.28358
https://doi.org/10.1556/hmj.2.2008.2.28358
Autor:
Harukuni, Tokuda, Takashi, Maoka, Nobutaka, Suzuiki, Judit, Hohmann, Andrea, Vasas, Helga, Engi, Ilona, Mucsi, Ulrike, Olszewski, Gerhard, Hamilton, Leonard, Amaral, Joseph, Molnar
Publikováno v:
Anticancer research. 33(5)
Morpholino-disiloxane (ALIS-409) and piperazino-disiloxane (ALIS-421) compounds were developed as inhibitors of multidrug resistance of various types of cancer cells. In the present study, the effects of ALIS-409 and ALIS-421 compounds were investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cfe0823ba3240ae60ade27f34d03466
https://pubmed.ncbi.nlm.nih.gov/23645751
https://pubmed.ncbi.nlm.nih.gov/23645751
Autor:
Helga Engi, Joseph Molnár, Qi Wang, Leonard Amaral, Attila Zalatnai, Ben Efraim Shlomo, Gabriela Spengler, Ilona Mucsi
Publikováno v:
Biochemistry & Pharmacology: Open Access.
Cancer grows at the expense of the host as a parasite or superparasite following the second law of thermodynamics (conservation of energy). When the cancer cell progresses via replication to the special state called “spheroid”, a new phase begins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f905160b1794bdaf2470bd7b02ea6821
https://doi.org/10.4172/2167-0501.1000107
https://doi.org/10.4172/2167-0501.1000107
Publikováno v:
In vivo (Athens, Greece). 23(5)
The activities of cell surface serine proteases are markedly enhanced in malignant tumours. Proteolytic degradation of the extracellular matrix and basal membrane of normal cells is an important event for tumour cell growth and invasion. Two well-kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e59eff1d7a43e3fc1fcb54c28a5814cf
https://pubmed.ncbi.nlm.nih.gov/19779105
https://pubmed.ncbi.nlm.nih.gov/19779105
Publikováno v:
In vivo (Athens, Greece). 22(6)
The development of strategies intended to inhibit human cytomegalovirus (HCMV) immediate-early (IE) antigen expression is an important goal in research designed to prevent and treat certain forms of cancer. The aim of this study was to identify poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27bd4bd1ce6a5f7b19a5b4d1d192bcfd
https://pubmed.ncbi.nlm.nih.gov/19181007
https://pubmed.ncbi.nlm.nih.gov/19181007
Autor:
Zsuzsanna Schelz, Judit Hohmann, Orsolya Kovács, Geng Gang, Dóra Rédei, Joseph Molnár, Helga Engi, Rozália Pusztai
Publikováno v:
Phytotherapy research : PTR. 22(12)
Many of the herbal extracts used in the Chinese clinical medical routine inhibit the growth of tumor cells. In the present work, extracts of 12 selected herbs were prepared with methanol, chloroform, ethyl acetate and water, and the effects of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cde1563f2474947436a55a65b55ec2
https://pubmed.ncbi.nlm.nih.gov/18690658
https://pubmed.ncbi.nlm.nih.gov/18690658