Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Helga, Refsum"'
Autor:
Per Ole Iversen, Jean‐Louis Gueant, Abderrahim Oussalah, Helga Refsum, Ebba Nexo, Geir E. Tjønnfjord, Christian Qvigstad
Publikováno v:
Clinical Case Reports, Vol 12, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Vitamin B12 deficiency is usually simple to diagnose. However, our patient demonstrates that in difficult cases, the ordinary clinician may need a transdisciplinary approach. The finding of a double haploinsufficiency as a possible cause of
Externí odkaz:
https://doaj.org/article/119d2ebc951f438783aae6a193714b17
Autor:
Thomas Olsen, Kathrine J. Vinknes, Kristýna Barvíková, Emma Stolt, Sindre Lee-Ødegård, Hannibal Troensegaard, Hanna Johannessen, Amany Elshorbagy, Jitka Sokolová, Jakub Krijt, Michaela Křížková, Tamás Ditrói, Péter Nagy, Bente Øvrebø, Helga Refsum, Magne Thoresen, Kjetil Retterstøl, Viktor Kožich
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103192- (2024)
Background: In animals, dietary sulfur amino acid restriction (SAAR) improves metabolic health, possibly mediated by altering sulfur amino acid metabolism and enhanced anti-obesogenic processes in adipose tissue. Aim: To assess the effects of SAAR ov
Externí odkaz:
https://doaj.org/article/25c59b32605a4c42bd104f1491f8959c
Autor:
Thomas Olsen, Emma Stolt, Bente Øvrebø, Amany Elshorbagy, Elena C. Tore, Sindre Lee-Ødegård, Hannibal Troensegaard, Hanna Johannessen, Beate Doeland, Anna A. D. Vo, Anja F. Dahl, Karianne Svendsen, Magne Thoresen, Helga Refsum, Russell Rising, Kristýna Barvíková, Marleen van Greevenbroek, Viktor Kožich, Kjetil Retterstøl, Kathrine J. Vinknes
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Dietary sulfur amino acid restriction (SAAR) improves metabolic health in animals. In this study, we investigated the effect of dietary SAAR on body weight, body composition, resting metabolic rate, gene expression profiles in whi
Externí odkaz:
https://doaj.org/article/ffd29a563d10426194fe0f90861628bb
Publikováno v:
The Lancet Global Health, Vol 10, Iss 10, Pp e1389- (2022)
Externí odkaz:
https://doaj.org/article/29baa7baeac643b4b0fc4a8c2c6d97bc
Autor:
Erik Fung, Kwan Hung Ng, Timothy Kwok, Leong-Ting Lui, Saranya Palaniswamy, Queenie Chan, Lee-Ling Lim, Petri Wiklund, Suyi Xie, Cheryl Turner, Amany K. Elshorbagy, Helga Refsum, Jason C. S. Leung, Alice P. S. Kong, Juliana C. N. Chan, Marjo-Riitta Järvelin, Jean Woo
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1252 (2023)
Branched-chain amino acids are critical metabolic intermediates that can indicate increased risk of cardiometabolic disease when levels are elevated or, alternatively, suggest sufficient mitochondrial energy metabolism and reserve in old age. The int
Externí odkaz:
https://doaj.org/article/18ba4a95fa5a4ea2852b595612e7db7a
Autor:
Emma Stolt, Thomas Olsen, Amany Elshorbagy, Viktor Kožich, Marleen van Greevenbroek, Bente Øvrebø, Magne Thoresen, Helga Refsum, Kjetil Retterstøl, Kathrine J. Vinknes
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background Dietary sulfur amino acid (SAA) restriction is an established animal model for increasing lifespan and improving metabolic health. Data from human studies are limited. In the study outlined in this protocol, we will evaluate if di
Externí odkaz:
https://doaj.org/article/8633d494d2174997953b3d11811e9b06
Autor:
Thomas Olsen, Bente Øvrebø, Cheryl Turner, Nasser E. Bastani, Helga Refsum, Kathrine J. Vinknes
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Objective In this 7-day pilot study we randomized healthy, normal-weight men and women to either a dietary intervention with methionine and cysteine restriction enriched in PUFA (Met/Cyslow + PUFA, n = 7) or with high contents of methionine,
Externí odkaz:
https://doaj.org/article/49a23801bb2c4aa29e12ef4acdc4e811
Autor:
Thomas Olsen, Cheryl Turner, Bente Øvrebø, Nasser E. Bastani, Helga Refsum, Kathrine J. Vinknes
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-7 (2020)
Abstract Objective The sulfur amino acid (SAA) cysteine is positively related, whereas polyunsaturated fatty acids (PUFAs) are inversely related to activity of the lipogenic enzyme stearoyl-CoA desaturase (SCD). High SCD activity promotes obesity in
Externí odkaz:
https://doaj.org/article/95a6e56956dd43ea8f3d42cc0a908e2d
Autor:
Thomas Olsen, Bente Øvrebø, Nadia Haj-Yasein, Sindre Lee, Karianne Svendsen, Marit Hjorth, Nasser E. Bastani, Frode Norheim, Christian A. Drevon, Helga Refsum, Kathrine J. Vinknes
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Dietary restriction of methionine and cysteine is a well-described model that improves metabolic health in rodents. To investigate the translational potential in humans, we evaluated the effects of dietary methionine and cysteine
Externí odkaz:
https://doaj.org/article/d09cf71393fe4c82874a4de4339fc362
Autor:
Olga Włoczkowska, Joanna Perła‐Kaján, A. David Smith, Celeste deJager, Helga Refsum, Hieronim Jakubowski
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Elevated homocysteine (Hcy) and related metabolites accelerate Alzheimer's disease. Hcy‐lowering B vitamins slow brain atrophy/cognitive decline in mild cognitive impairment (MCI). Modification with Hcy‐thiolactone generates
Externí odkaz:
https://doaj.org/article/e6341bc760d04e44993f4e98a80aa57d