Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges.

Autor: Lackner G; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, 8093 Zurich, Switzerland.; Junior Research Group Synthetic Microbiology, Friedrich Schiller University at the Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, 07745 Jena, Germany., Peters EE; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, 8093 Zurich, Switzerland., Helfrich EJ; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, 8093 Zurich, Switzerland., Piel J; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, 8093 Zurich, Switzerland; jpiel@ethz.ch.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Jan 17; Vol. 114 (3), pp. E347-E356. Date of Electronic Publication: 2017 Jan 03.

Biosynthesis of polyketides by trans-AT polyketide synthases.

Autor: Helfrich EJ; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland. jpiel@ethz.ch., Piel J; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland. jpiel@ethz.ch.

Publikováno v: Natural product reports [Nat Prod Rep] 2016 Feb; Vol. 33 (2), pp. 231-316.

Minimum Information about a Biosynthetic Gene cluster.

Autor: Medema MH; Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany., Kottmann R; Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany., Yilmaz P; Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany., Cummings M; Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK., Biggins JB; Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA., Blin K; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark., de Bruijn I; Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands., Chooi YH; 1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA. [3] School of Chemistry and Biochemistry, University of Western Australia, Perth, Western Australia, Australia., Claesen J; 1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA., Coates RC; Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA., Cruz-Morales P; Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México., Duddela S; Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany., Düsterhus S; Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany., Edwards DJ; Department of Chemistry and Biochemistry, California State University, Chico, California, USA., Fewer DP; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland., Garg N; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA., Geiger C; Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany., Gomez-Escribano JP; Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK., Greule A; Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany., Hadjithomas M; Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA., Haines AS; School of Biosciences, University of Birmingham, Birmingham, UK., Helfrich EJ; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland., Hillwig ML; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ishida K; Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany., Jones AC; Gordon and Betty Moore Foundation, Palo Alto, California, USA., Jones CS; Sustainable Studies Program, Roosevelt University Chicago, Illinois, USA., Jungmann K; Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany., Kegler C; Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany., Kim HU; 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] BioInformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea., Kötter P; Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany., Krug D; Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany., Masschelein J; 1] Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium. [2] Laboratory of Food Microbiology, KU Leuven, Heverlee, Belgium., Melnik AV; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA., Mantovani SM; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA., Monroe EA; Department of Biology, William Paterson University, Wayne, New Jersey, USA., Moore M; Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada., Moss N; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA., Nützmann HW; Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK., Pan G; Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA., Pati A; Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA., Petras D; Institut für Chemie, Technische Universität Berlin, Berlin, Germany., Reen FJ; BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland., Rosconi F; Departamento de Bioquímica y Genómica Microbianas, IBCE, Montevideo, Uruguay., Rui Z; 1] Energy Biosciences Institute, University of California Berkeley, Berkeley, California, USA. [2] Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California, USA., Tian Z; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Tobias NJ; Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany., Tsunematsu Y; 1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Wiemann P; Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA., Wyckoff E; 1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA., Yan X; Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA., Yim G; Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Yu F; 1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA., Xie Y; Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China., Aigle B; Dynamique des Génomes et Adaptation Microbienne, Université de Lorraine and Institut National de la Recherche Agronomique (INRA), Unité Mixte de Recherche (UMR) 1128, Vandœuvre-lès-Nancy, France., Apel AK; 1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany., Balibar CJ; Infectious Disease Research, Merck Research Laboratories, Kenilworth, New Jersey, USA., Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA., Barona-Gómez F; Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México., Bechthold A; Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany., Bode HB; 1] Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany. [2] Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt, Frankfurt, Germany., Borriss R; Fachbereich Phytomedizin, Albrecht Thaer Institut, Humboldt Universität Berlin, Berlin, Germany., Brady SF; Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA., Brakhage AA; Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany., Caffrey P; UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland., Cheng YQ; UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, USA., Clardy J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA., Cox RJ; 1] Institut für Organische Chemie, Leibniz Universität Hannover, Hannover, Germany. [2] School of Chemistry, University of Bristol, Bristol, UK., De Mot R; Centre of Microbial and Plant Genetics, Faculty of Bioscience Engineering, University of Leuven, Heverlee, Belgium., Donadio S; Naicons Srl, Milano, Italy., Donia MS; Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA., van der Donk WA; 1] Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA. [2] Howard Hughes Medical Institute, USA., Dorrestein PC; 1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA. [3] Collaborative Mass Spectrometry Innovation Center, University of California San Diego, La Jolla, California, USA., Doyle S; Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland., Driessen AJ; Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen, the Netherlands., Ehling-Schulz M; Functional Microbiology, Institute of Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria., Entian KD; Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany., Fischbach MA; 1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA., Gerwick L; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA., Gerwick WH; 1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA., Gross H; 1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany., Gust B; 1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany., Hertweck C; 1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Friedrich Schiller University, Jena, Germany., Höfte M; Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Jensen SE; Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada., Ju J; Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China., Katz L; Synthetic Biology Engineering Research Center (SynBERC), University of California Emeryville, Emeryville, California, USA., Kaysser L; 1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany., Klassen JL; Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA., Keller NP; 1] Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA., Kormanec J; Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovak Republic., Kuipers OP; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands., Kuzuyama T; Biotechnology Research Center, The University of Tokyo, Tokyo, Japan., Kyrpides NC; 1] Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA. [2] Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Kwon HJ; Division of Bioscience and Bioinformatics, Myongji University, Yongin-si, Gyeonggi-Do, South Korea., Lautru S; Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France., Lavigne R; Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium., Lee CY; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA., Linquan B; 1] State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China. [2] School of Life Sciences &Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Liu X; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Liu W; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China., Luzhetskyy A; Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany., Mahmud T; Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon, USA., Mast Y; Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany., Méndez C; 1] Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain. [2] Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain., Metsä-Ketelä M; Department of Biochemistry, University of Turku, Turku, Finland., Micklefield J; School of Chemistry, University of Manchester, Manchester, UK., Mitchell DA; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA., Moore BS; 1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA., Moreira LM; Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal., Müller R; Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany., Neilan BA; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia., Nett M; Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany., Nielsen J; 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., O'Gara F; 1] BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland. [2] Curtin University, School of Biomedical Sciences, Perth, Western Australia, Australia., Oikawa H; Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo, Japan., Osbourn A; Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK., Osburne MS; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Ostash B; Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv, Ukraine., Payne SM; 1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA., Pernodet JL; Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France., Petricek M; Institute of Microbiology, Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic., Piel J; Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland., Ploux O; Laboratoire Interdisciplinaire des Energies de Demain (LIED), UMR 8236 CNRS, Université Paris Diderot, Paris, France., Raaijmakers JM; Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands., Salas JA; Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain., Schmitt EK; Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland., Scott B; Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand., Seipke RF; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Shen B; 1] Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA. [2] Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter, Florida, USA., Sherman DH; 1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA., Sivonen K; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland., Smanski MJ; 1] Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA. [2] BioTechnology Institute, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA., Sosio M; Naicons Srl, Milano, Italy., Stegmann E; 1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany., Süssmuth RD; Institut für Chemie, Technische Universität Berlin, Berlin, Germany., Tahlan K; Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada., Thomas CM; School of Biosciences, University of Birmingham, Birmingham, UK., Tang Y; 1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA., Truman AW; Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK., Viaud M; Unité BIOlogie et GEstion des Risques en agriculture (BIOGER), Institut National de la Recherche Agronomique (INRA), Grignon, France., Walton JD; Department of Energy Great Lakes Bioenergy Research Center and Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA., Walsh CT; Chemistry, Engineering &Medicine for Human Health (ChEM-H) Institute, Stanford University, Stanford, California, USA., Weber T; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark., van Wezel GP; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands., Wilkinson B; Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK., Willey JM; Hofstra North Shore-Long Island Jewish School of Medicine, Hempstead, New York, USA., Wohlleben W; 1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany., Wright GD; Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Ziemert N; 1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany., Zhang C; Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China., Zotchev SB; Department of Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway., Breitling R; Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK., Takano E; Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK., Glöckner FO; 1] Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany. [2] Jacobs University Bremen gGmbH, Bremen, Germany.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2015 Sep; Vol. 11 (9), pp. 625-31.

Recent advances in genome-based polyketide discovery.

Autor: Helfrich EJ; Institute of Microbiology, Swiss Federal Institute of Technology Zurich (ETH), Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland., Reiter S; Institute of Microbiology, Swiss Federal Institute of Technology Zurich (ETH), Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland., Piel J; Institute of Microbiology, Swiss Federal Institute of Technology Zurich (ETH), Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland. Electronic address: jpiel@ethz.ch.

Publikováno v: Current opinion in biotechnology [Curr Opin Biotechnol] 2014 Oct; Vol. 29, pp. 107-15. Date of Electronic Publication: 2014 Apr 22.

Matrix-free single-cell LDI-MS investigations of the diatoms Coscinodiscus granii and Thalassiosira pseudonana.

Autor: Jaschinski T; Institute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, Lessingstraße 8, 07743, Jena, Germany., Helfrich EJ, Bock C, Wolfram S, Svatoš A, Hertweck C, Pohnert G

Publikováno v: Journal of mass spectrometry : JMS [J Mass Spectrom] 2014 Feb; Vol. 49 (2), pp. 136-44.