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of 3
pro vyhledávání: '"Heley Ong"'
Autor:
Guangai Xue, Klaudia Braczyk, Daniel Gonçalves-Carneiro, Daria M Dawidziak, Katarzyna Sanchez, Heley Ong, Yueping Wan, Kaneil K Zadrozny, Barbie K Ganser-Pornillos, Paul D Bieniasz, Owen Pornillos
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1009202 (2022)
Zinc-finger antiviral protein (ZAP), also known as poly(ADP-ribose) polymerase 13 (PARP13), is an antiviral factor that selectively targets viral RNA for degradation. ZAP is active against both DNA and RNA viruses, including important human pathogens
Externí odkaz:
https://doaj.org/article/818e8e6cae384fec8434905356ad25de
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009545 (2021)
The human zinc finger antiviral protein (ZAP) recognizes RNA by binding to CpG dinucleotides. Mammalian transcriptomes are CpG-poor, and ZAP may have evolved to exploit this feature to specifically target non-self viral RNA. Phylogenetic analyses rev
Externí odkaz:
https://doaj.org/article/4e68ecf0faba435a922b2a5c40f6cc45
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 4, p e1009545 (2021)
PLoS Pathogens, Vol 17, Iss 4, p e1009545 (2021)
The human zinc finger antiviral protein (ZAP) recognizes RNA by binding to CpG dinucleotides. Mammalian transcriptomes are CpG-poor, and ZAP may have evolved to exploit this feature to specifically target non-self viral RNA. Phylogenetic analyses rev