Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Helene Marbach"'
Autor:
Anna Walzl, Helene Marbach, Darya Belikova, Claus Vogl, Monika Ehling-Schulz, Simon Heilbronner, Tom Grunert
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 699 (2023)
Phenotypic adaptation has been associated with persistent, therapy-resistant Staphylococcus aureus infections. Recently, we described within-host evolution towards a Sigma factor B (SigB)-deficient phenotype in a non-human host, a naturally infected
Externí odkaz:
https://doaj.org/article/d4ff645a031642868ab0cc35098c834e
Autor:
Katharina Mayer, Martin Kucklick, Helene Marbach, Monika Ehling-Schulz, Susanne Engelmann, Tom Grunert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8840 (2021)
Within-host adaptation is a typical feature of chronic, persistent Staphylococcus aureus infections. Research projects addressing adaptive changes due to bacterial in-host evolution increase our understanding of the pathogen’s strategies to survive
Externí odkaz:
https://doaj.org/article/db225fce68ea48caab22cb46d7e25e76
Autor:
Olga Tosas Auguet, Jason R Betley, Richard A Stabler, Amita Patel, Avgousta Ioannou, Helene Marbach, Pasco Hearn, Anna Aryee, Simon D Goldenberg, Jonathan A Otter, Nergish Desai, Tacim Karadag, Chris Grundy, Michael W Gaunt, Ben S Cooper, Jonathan D Edgeworth, Theodore Kypraios
Publikováno v:
PLoS Medicine, Vol 13, Iss 1, p e1001944 (2016)
BackgroundIdentifying and tackling the social determinants of infectious diseases has become a public health priority following the recognition that individuals with lower socioeconomic status are disproportionately affected by infectious diseases. I
Externí odkaz:
https://doaj.org/article/5ed19960f52b435a93a748b78347c773
Autor:
Thomas Guttenberg, Hala Youssef, Helene Marbach, Chen Shen, Gema Vizcay-Barrena, Christian Wölk, Richard D. Harvey, Gerald Brezesinski
Publikováno v:
ChemPhysChem 21(8), 702-706 (2020). doi:10.1002/cphc.202000026
ChemPhysChem
Chemphyschem
ChemPhysChem
Chemphyschem
ChemPhysChem 21(8), 702 - 706 (2020). doi:10.1002/cphc.202000026
Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol – PG and lysyl‐phosphatidylglycerol – LPG) confers resistance t
Ion pairing between the major phospholipids of the Staphylococcus aureus plasma membrane (phosphatidylglycerol – PG and lysyl‐phosphatidylglycerol – LPG) confers resistance t
Brake dust exposure exacerbates inflammation and transiently compromises phagocytosis in macrophages
Autor:
Liza Selley, Ian Mudway, Nuria Camiña, Thomas Sandström, Abhinav Kumar, Theresa Forsthuber, Toby J. Athersuch, Helene Marbach, Linda C. Schuster, Timothy W. Gant, Ben Forbes
Publikováno v:
Metallomics. 12:371-386
Studies have emphasised the importance of combustion-derived particles in eliciting adverse health effects, especially those produced by diesel vehicles. In contrast, few investigations have explored the potential toxicity of particles derived from t
Autor:
Helene Marbach, Katharina Mayer, Claus Vogl, Jean Y. H. Lee, Ian R. Monk, Daniel O. Sordelli, Fernanda R. Buzzola, Monika Ehling-Schulz, Tom Grunert
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Staphylococcus aureus is a major cause of bovine mastitis, commonly leading to long-lasting, persistent and recurrent infections. Thereby, S. aureus constantly refines and permanently adapts to the bovine udder environment. In this work, we followed
Autor:
Fruzsina Irén, Antók, Rosa, Mayrhofer, Helene, Marbach, Jean Claude, Masengesho, Helga, Keinprecht, Vedaste, Nyirimbuga, Otto, Fischer, Sarah, Lepuschitz, Werner, Ruppitsch, Monika, Ehling-Schulz, Andrea T, Feßler, Stefan, Schwarz, Stefan, Monecke, Ralf, Ehricht, Tom, Grunert, Joachim, Spergser, Igor, Loncaric
Publikováno v:
Antibiotics
The present study was conducted from July to August 2018 on milk samples taken at dairy farms in the Northern Province and Kigali District of Rwanda in order to identify Staphylococcus spp. associated with bovine intramammary infection. A total of 16
Autor:
Helene Marbach, Federica Sebastiani, Giovanna Fragneto, Anam A. Sacranie, Alasdair T. M. Hubbard, Richard D. Harvey, Reg Rehal
Publikováno v:
Rehal, R P, Marbach, H, Hubbard, A T M, Sacranie, A A, Sebastiani, F, Fragneto, G & Harvey, R D 2017, ' The influence of mild acidity on lysyl-phosphatidylglycerol biosynthesis and lipid membrane physico-chemical properties in methicillin-resistant Staphylococcus aureus ', Chemistry and Physics of Lipids . https://doi.org/10.1016/j.chemphyslip.2017.06.007
The increased biosynthesis of lysyl-phosphatidylglycerol in Staphylococcus aureus when cultured under conditions of mild acidity and the resultant increased proportion of this lipid in the plasma membrane of the bacterium, alters the physico-chemical
Autor:
Jonathan A. Otter, Eve Boakes, Malcolm Ward, Steven Lynham, Jonathan D. Edgeworth, Helene Marbach
Publikováno v:
Journal of Medical Microbiology. 66:584-591
Purpose. We previously identified an association between CC22 meticillin-resistant Staphylococcus aureus (MRSA) bloodstream infection isolates with an elevated vancomycin MIC (V-MIC) in the susceptible range (1.5–2 mg l−1) and endocarditis. This
Autor:
Jonathan A. Otter, Kaveh Memarzadeh, Helene Marbach, Robert P. Allaker, Jonathan D. Edgeworth, Richard D. Harvey, Smriti Pathak, Gema Vizcay-Barrena
Publikováno v:
Marbach, H, Vizcay-Barrena, G, Memarzadeh, K, Otter, J A, Pathak, S, Allaker, R P, Harvey, R D & Edgeworth, J D 2018, ' Tolerance of MRSA ST239-TW to chlorhexidine-based decolonization; evidence for keratinocyte invasion as a mechanism of biocide evasion ', Journal of Infection . https://doi.org/10.1016/j.jinf.2018.10.007
Information on genetic determinants of chlorhexidine tolerance (qacA carriage and MIC) in vitro is available, although evidence of the clinical impact and mechanisms remain poorly understood. We investigated why, following chlorhexidine intervention,