Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Helene M Ægidius"'
Autor:
Henrik H. Hansen, Helene M. Ægidius, Denise Oró, Simon S. Evers, Sara Heebøll, Peter Lykke Eriksen, Karen Louise Thomsen, Anja Bengtsson, Sanne S. Veidal, Michel Feigh, Malte P. Suppli, Filip K. Knop, Henning Grønbæk, Diego Miranda, James L. Trevaskis, Niels Vrang, Jacob Jelsing, Kristoffer T. G. Rigbolt
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study dir
Externí odkaz:
https://doaj.org/article/738511df0fdc4d36be87fd7875e0fda9
Autor:
Frederikke E. Sembach, Helene M. Ægidius, Lisbeth N. Fink, Thomas Secher, Annemarie Aarup, Jacob Jelsing, Niels Vrang, Bo Feldt-Rasmussen, Kristoffer T. G. Rigbolt, Jens C. Nielsen, Mette V. Østergaard
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
The current understanding of molecular mechanisms driving diabetic kidney disease (DKD) is limited, partly due to the complex structure of the kidney. To identify genes and signalling pathways involved in the progression of DKD, we compared kidney co
Externí odkaz:
https://doaj.org/article/81d68d895ca048628b90770834252305
Autor:
Niels Vrang, Michele Puglia, Tune H. Pers, Birgitte Rahbek Kornum, Michael Feigh, Helene M Ægidius, Jacob Jelsing, Philip Hallenborg, Sanne Skovgård Veidal, Blagoy Blagoev, Kristoffer T.G. Rigbolt
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Ægidius, H M, Veidal, S S, Feigh, M, Hallenborg, P, Puglia, M, Pers, T H, Vrang, N, Jelsing, J, Kornum, B R, Blagoev, B & Rigbolt, K T G 2020, ' Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis ', Scientific Reports, vol. 10, no. 1, 1148 . https://doi.org/10.1038/s41598-020-58059-7
Scientific Reports
Ægidius, H M, Veidal, S S, Feigh, M, Hallenborg, P, Puglia, M, Pers, T H, Vrang, N, Jelsing, J, Kornum, B R, Blagoev, B & Rigbolt, K T G 2020, ' Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis ', Scientific Reports, vol. 10, no. 1, 1148 . https://doi.org/10.1038/s41598-020-58059-7
Scientific Reports
To improve the understanding of the complex biological processes underlying the development of non-alcoholic steatohepatitis (NASH), a multi-omics approach combining bulk RNA-sequencing based transcriptomics, quantitative proteomics and single-cell R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c55c07b520910373ed7da73108ed82
http://link.springer.com/article/10.1038/s41598-020-58059-7
http://link.springer.com/article/10.1038/s41598-020-58059-7
Autor:
Annemarie Aarup, Bo Feldt-Rasmussen, Helene M Ægidius, Thomas Secher, Lisbeth Nielsen Fink, Frederikke E. Sembach, Jens Nielsen, Niels Vrang, Jacob Jelsing, Kristoffer T.G. Rigbolt, Mette V. Østergaard
Publikováno v:
Sembach, F E, Agidius, H M, Fink, L N, Secher, T, Aarup, A, Jelsing, J, Vrang, N, Feldt-Rasmussen, B, Rigbolt, K T G, Nielsen, J C & Østergaard, M V 2021, ' Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease ', DMM Disease Models and Mechanisms, vol. 14, no. 10, dmm049086 . https://doi.org/10.1242/dmm.049086
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
The current understanding of molecular mechanisms driving diabetic kidney disease (DKD) is limited, partly due to the complex structure of the kidney. To identify genes and signalling pathways involved in the progression of DKD, we compared kidney co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ba84935ffe3e2e8964eb58d8e8bba4
https://doi.org/10.1242/dmm.049086
https://doi.org/10.1242/dmm.049086
Autor:
Giuseppe Plazzi, Helene M Ægidius, Gitte Lund Christensen, Poul Jennum, Niklas Rye Jørgensen, Marc P Lorentzen, Birgitte Rahbek Kornum, Monica Moresco, Lars S Kruse, Fabio Pizza
Publikováno v:
Brain Communications
The hypocretin/orexin system regulates arousal through central nervous system mechanisms and plays an important role in sleep, wakefulness and energy homeostasis. It is unclear whether hypocretin peptides are also present in blood due to difficulties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3476a8b7c479b237489f82017d5d167
https://hdl.handle.net/11380/1270905
https://hdl.handle.net/11380/1270905
Autor:
Niels Vrang, Henning Grønbæk, Anja Bengtsson, Helene M Ægidius, Michel Feigh, Henrik H. Hansen, James L. Trevaskis, Jacob Jelsing, Karen Louise Thomsen, Sanne Skovgård Veidal, Diego A. Miranda, Malte P. Suppli, Filip K. Knop, Peter Lykke Eriksen, Kristoffer T.G. Rigbolt, Sara Heebøll, Denise Oró, Simon S. Evers
Publikováno v:
Hansen, H H, Ægidius, H M, Oró, D, Evers, S S, Heebøll, S, Eriksen, P L, Thomsen, K L, Bengtsson, A, Veidal, S S, Feigh, M, Suppli, M P, Knop, F K, Grønbæk, H, Miranda, D, Trevaskis, J L, Vrang, N, Jelsing, J & Rigbolt, K T G 2020, ' Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis ', BMC Gastroenterology, vol. 20, no. 1, 210 . https://doi.org/10.1186/s12876-020-01356-2
BMC Gastroenterology
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-12 (2020)
Hansen, H H, Aegidius, H M, Oro, D, Evers, S S, Heeboll, S, Eriksen, P L, Thomsen, K L, Bengtsson, A, Veidal, S S, Feigh, M, Suppli, M P, Knop, F K, Gronbaek, H, Miranda, D, Trevaskis, J L, Vrang, N, Jelsing, J & Rigbolt, K T G 2020, ' Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis ', B M C Gastroenterology, vol. 20, 210 . https://doi.org/10.1186/s12876-020-01356-2
BMC Gastroenterology
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-12 (2020)
Hansen, H H, Aegidius, H M, Oro, D, Evers, S S, Heeboll, S, Eriksen, P L, Thomsen, K L, Bengtsson, A, Veidal, S S, Feigh, M, Suppli, M P, Knop, F K, Gronbaek, H, Miranda, D, Trevaskis, J L, Vrang, N, Jelsing, J & Rigbolt, K T G 2020, ' Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis ', B M C Gastroenterology, vol. 20, 210 . https://doi.org/10.1186/s12876-020-01356-2
Background Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH. The present study directly ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b063b9e216e2690108ac64532fd16407
https://pure.au.dk/portal/da/publications/human-translatability-of-the-gan-dietinduced-obese-mouse-model-of-nonalcoholic-steatohepatitis(fd5a2346-a000-4887-a309-0c5d648e817c).html
https://pure.au.dk/portal/da/publications/human-translatability-of-the-gan-dietinduced-obese-mouse-model-of-nonalcoholic-steatohepatitis(fd5a2346-a000-4887-a309-0c5d648e817c).html