Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Helene Kolstad Skovdahl"'
Autor:
Shreya Gopalakrishnan, Ingunn Bakke, Marianne Doré Hansen, Helene Kolstad Skovdahl, Atle van Beelen Granlund, Arne K. Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
There are many unanswered questions regarding responses to proinflammatory signals in intestinal epithelial cells (IECs). For example, chemokines secreted by IECs upon external stimuli play multifunctional roles in both homeostasis and during inflamm
Externí odkaz:
https://doaj.org/article/1c8497207a054ee8830b29b10212250a
Autor:
Gunnar Andreas Walaas, Shreya Gopalakrishnan, Ingunn Bakke, Helene Kolstad Skovdahl, Arnar Flatberg, Ann Elisabet Østvik, Arne Kristian Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe epithelium in the colonic mucosa is implicated in the pathophysiology of various diseases, including inflammatory bowel diseases and colorectal cancer. Intestinal epithelial organoids from the colon (colonoids) can be used for disease m
Externí odkaz:
https://doaj.org/article/01ada229198b4632b1acd85dc3ea4dd7
Autor:
Shreya Gopalakrishnan, Marianne Doré Hansen, Helene Kolstad Skovdahl, Ingrid Aass Roseth, Atle van Beelen Granlund, Ann Elisabet Østvik, Ingunn Bakke, Arne Kristian Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Major Histocompatibility Complex (MHC)-I and -II genes are upregulated in intestinal epithelial cells (IECs) during active inflammatory bowel diseases (IBD), but little is known about how IBD-relevant pro-inflammatory signals and IBD drugs can regula
Externí odkaz:
https://doaj.org/article/89a246f92a1147c7afde661523747fdc
Autor:
Helene Kolstad Skovdahl, Shreya Gopalakrishnan, Tarjei Dahl Svendsen, Atle van Beelen Granlund, Ingunn Bakke, Zekarias G. Ginbot, Silje Thorsvik, Arnar Flatberg, Bjørnar Sporsheim, Jenny Ostrop, Tom Eirik Mollnes, Arne Kristian Sandvik, Torunn Bruland
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Treatment of inflammatory bowel disease (IBD) is challenging, with a series of available drugs each helping only a fraction of patients. Patients may face time-consuming drug trials while the disease is active, thus there is an unmet need for biomark
Externí odkaz:
https://doaj.org/article/23107a23c1a647daa8ee051009ee1d4a
Autor:
Helene Kolstad Skovdahl, Atle van Beelen Granlund, Ann Elisabet Østvik, Torunn Bruland, Ingunn Bakke, Sverre Helge Torp, Jan Kristian Damås, Arne Kristian Sandvik
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141710 (2015)
The chemokine CCL20 and its receptor CCR6 are putative drug targets in inflammatory bowel disease, and CCL20 is a novel IBD predilection gene. Previous findings on the CCL20 response in these diseases are divergent. This study was undertaken to exami
Externí odkaz:
https://doaj.org/article/2ad252640ed742f283639bd6a9d181b4
Autor:
Siri Sæterstad, Silje Thorsvik, Helene Kolstad Skovdahl, Arne K. Sandvik, Benedikt Kornfeld, Jonas Woll Jørandli, Bjorn I. Gustafsson, Atle van Beelen Granlund
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 319(6)
Serotonin is a highly conserved and ubiquitous signaling molecule involved in a vast variety of biological processes. A majority of serotonin is produced in the gastrointestinal epithelium, where it is suggested to act as a prominent regulatory molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe213aa0b2f883b6d4aaf88e70bc263
https://pubmed.ncbi.nlm.nih.gov/32967429
https://pubmed.ncbi.nlm.nih.gov/32967429
Autor:
Wahida Afroz, Helene Kolstad Skovdahl, Gunnar Andreas Walaas, Tarjei Dahl Svendsen, Ingunn Bakke, Torunn Bruland, Berit Doseth, Bjorn I. Gustafsson, Silje Thorsvik, Arne K. Sandvik, Ann Elisabet Østvik, Tom Eirik Mollnes, Atle van Beelen Granlund
Publikováno v:
Journal of Crohn's & Colitis
Journal of Crohn's and colitis
Journal of Crohn's and colitis
Background and Aims Intestinal epithelial cells [IECs] secrete cytokines that recruit immune cells to the mucosa and regulate immune responses that drive inflammation in inflammatory bowel disease [IBD]. However, experiments in patient-derived IEC mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dd8b7af1b379f642d3f40449976c9b
http://hdl.handle.net/10852/82098
http://hdl.handle.net/10852/82098
Autor:
S Gopalakrishnan, K S Eriksen, Arne K. Sandvik, Silje Thorsvik, A.E. Østvik, Torunn Bruland, Atle van Beelen Granlund, Ingunn Bakke, Helene Kolstad Skovdahl
Publikováno v:
Journal of Crohn's and Colitis. 14:S182-S182
Background The nuclear receptor peroxisome proliferation-activated receptor γ (PPARγ) harbours anti-inflammatory effects. There is evidence that PPARγ mediates the effect of 5-aminosalicylic acid (5-ASA). 5-ASA is the first-line drug in ulcerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::330177645e327ed46bcb7e4753e4d769
https://doi.org/10.1093/ecco-jcc/jjz203.223
https://doi.org/10.1093/ecco-jcc/jjz203.223
Autor:
Arne K. Sandvik, Jan Kristian Damås, Ann Elisabet Østvik, Atle van Beelen Granlund, Tom Eirik Mollnes, Helene Kolstad Skovdahl, Berit Doseth, Torunn Bruland
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3257 (2018)
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3257 (2018)
Volume 19
Issue 10
The chemokine C-C motif ligand 20 (CCL20) is increased in the colonic mucosa during active inflammatory bowel disease (IBD) and can be found both in the epithelium and immune cells in the lamina propria. The present study investigated CCL20 and C-C m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72dfd5bf0641b917ff0c121f66892234
http://hdl.handle.net/11250/2574594
http://hdl.handle.net/11250/2574594
Autor:
Arne K. Sandvik, Tom Eirik Mollnes, J K Damaas, Berit Doseth, A.E. Østvik, Torunn Bruland, Atle van Beelen Granlund, Helene Kolstad Skovdahl
Publikováno v:
Journal of Crohn's and Colitis. 12:S140-S141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6673903e174519ec1c4fb434b3e5225
https://doi.org/10.1093/ecco-jcc/jjx180.220
https://doi.org/10.1093/ecco-jcc/jjx180.220