Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helene Jahn"'
Autor:
Helene Jahn, Ladislav Bartoš, Grace I. Dearden, Jeremy S. Dittman, Joost C. M. Holthuis, Robert Vácha, Anant K. Menon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mitochondria are double-membrane-bounded organelles that depend critically on phospholipids supplied by the endoplasmic reticulum. These lipids must cross the outer membrane to support mitochondrial function, but how they do this is unclear.
Externí odkaz:
https://doaj.org/article/80090a11e13246b496e3a818de0be8af
Autor:
Shashank Dadsena, Svenja Bockelmann, John G. M. Mina, Dina G. Hassan, Sergei Korneev, Guilherme Razzera, Helene Jahn, Patrick Niekamp, Dagmar Müller, Markus Schneider, Fikadu G. Tafesse, Siewert J. Marrink, Manuel N. Melo, Joost C. M. Holthuis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Ceramides are lipids that act directly on mitochondria to trigger apoptosis, but the underlying mechanism remains largely unclear. Here authors use a photoactivatable ceramide probe combined with a computation approach and functional studies to ident
Externí odkaz:
https://doaj.org/article/161032635f8246f6afb463a1fd58d74b
Mitochondria depend on phospholipids supplied by the endoplasmic reticulum, but how these lipids cross the outer membrane to enter mitochondria is unclear. We identified the voltage-dependent ion channel (VDAC) as a scramblase that facilitates lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80828ca05678219ff882d99a98a98ba3
https://doi.org/10.1101/2022.10.17.512472
https://doi.org/10.1101/2022.10.17.512472
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
The autophagy protein ATG2, proposed to transfer bulk lipid from the endoplasmic reticulum (ER) during autophagosome biogenesis, interacts with ER residents TMEM41B and VMP1 and with ATG9, in Golgi-derived vesicles that initiate autophagosome formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4550aa3a601d851cf56dcb0fb4c85ce
https://doi.org/10.12703/r-01-0000015
https://doi.org/10.12703/r-01-0000015
Autor:
Dina G Hassan, Dagmar Müller, Patrick Niekamp, Siewert J. Marrink, Shashank Dadsena, Guilherme Razzera, Markus Schneider, Sergei Korneev, Manuel N. Melo, Joost C. M. Holthuis, John G. Mina, Helene Jahn, Svenja Bockelmann, Fikadu G. Tafesse
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, 10(1):1832. Nature Publishing Group
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, 10(1):1832. Nature Publishing Group
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Ceramides draw wide attention as tumor suppressor lipids that act directly on mitochondria to trigger apoptotic cell death. However, molecular details of the underlying mechanism are largely unknown. Using a photoactivatable ceramide probe, we here i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3790622a3c6c1797871e9a1e543de07
https://doi.org/10.1038/s41467-019-09654-4
https://doi.org/10.1038/s41467-019-09654-4
Autor:
Barend O. W. Elenbaas, Helene Jahn, Adrian H. Kopf, J. Antoinette Killian, Martijn C. Koorengevel
Publikováno v:
Biophysical Journal. 118:230a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c8dc3a6509df284433d1c2da2afecb
https://doi.org/10.1016/j.bpj.2019.11.1361
https://doi.org/10.1016/j.bpj.2019.11.1361
Autor:
Min Xie, Martijn C. Koorengevel, Jonas M. Dörr, Helene Jahn, Antoinette Killian, Adrian H. Kopf, Rueben Pfukwa, Bert Klumperman, Randy D Cunningham
Publikováno v:
Biophysical Journal. 116:82a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fde1453154cf22413fa03122478ffae
https://doi.org/10.1016/j.bpj.2018.11.487
https://doi.org/10.1016/j.bpj.2018.11.487