Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Helene Chapy"'
Autor:
Luigi Brunetti, Helene Chapy, Ronald G. Nahass, Rebecca Moore, Andrew Wassef, Derek Adler, Edward Yurkow, Leonid Kagan
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 510 (2023)
The purpose of this study was to investigate the effect of obesity on immunoglobulin G (IgG) pharmacokinetics in a rat model of obesity, and to collect clinical evidence for an association between the body composition and intravenous immune globulin
Externí odkaz:
https://doaj.org/article/e40f30d27a924d85ac1826eafc73dca8
Autor:
Olivier Nicolas, Sabine Gerbal-Chaloin, Priscilla Brun, Sylvie Klieber, Xavier Boulenc, Helene Chapy
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:491-506
Physiological based pharmacokinetic (PBPK) modeling is now commonly used in drug development to integrate human or animal physiological data in order to predict pharmacokinetic profiles. The aim of this work was to construct and refine a PBPK model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ccf7efbbebd32eca173fc0f5be82084
https://doi.org/10.1002/bdd.1961
https://doi.org/10.1002/bdd.1961
Autor:
Helene, Chapy, Sylvie, Klieber, Priscilla, Brun, Sabine, Gerbal-Chaloin, Xavier, Boulenc, Olivier, Nicolas
Publikováno v:
Biopharmaceuticsdrug disposition. 36(8)
Physiological based pharmacokinetic (PBPK) modeling is now commonly used in drug development to integrate human or animal physiological data in order to predict pharmacokinetic profiles. The aim of this work was to construct and refine a PBPK model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5eef2afd42e88acfea923726f08a1193
https://pubmed.ncbi.nlm.nih.gov/26037524
https://pubmed.ncbi.nlm.nih.gov/26037524
Autor:
Maria Smirnova, Laura Goracci, Gabriele Cruciani, Laetitia Federici, Xavier Declèves, Hélène Chapy, Salvatore Cisternino
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 255 (2022)
A drug/proton-antiporter, whose the molecular structure is still unknown, was previously evidenced at the blood-brain barrier (BBB) by functional experiments. The computational method could help in the identification of substrates of this solute carr
Externí odkaz:
https://doaj.org/article/18cadf88589844d89c2a221699e09882
Autor:
Catarina Chaves, Federica Campanelli, Hélène Chapy, David Gomez-Zepeda, Fabienne Glacial, Maria Smirnova, Meryam Taghi, Johan Pallud, Nicolas Perrière, Xavier Declèves, Marie-Claude Menet, Salvatore Cisternino
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 308 (2020)
Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear. The presence of OCT1,2,3 (SLC22A1-3) in mouse, rat
Externí odkaz:
https://doaj.org/article/c2afaafc389e4db8b9cc11af61128488