Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Helene C. Highbarger"'
Autor:
Jun Yang, Ming Hao, Muhammad A. Khan, Muhammad T. Rehman, Helene C. Highbarger, Qian Chen, Suranjana Goswami, Brad T. Sherman, Catherine A. Rehm, Robin L. Dewar, Weizhong Chang, Tomozumi Imamichi
Publikováno v:
Viruses, Vol 13, Iss 11, p 2331 (2021)
We have recently reported that a recombinant HIV-1NL4.3 containing Met-to-Ile change at codon 50 of integrase (IN) (IN:M50I) exhibits suppression of the virus release below 0.5% of WT HIV, and the released viral particles are replication-incompetent
Externí odkaz:
https://doaj.org/article/d3ccaabb87b0429cb3c47bc2cede4361
Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19:A Randomized Controlled Trial
Autor:
Christina, Barkauskas, Eleftherios, Mylonakis, Garyfallia, Poulakou, Barnaby E, Young, David M, Vock, Lianne, Siegel, Nicole, Engen, Greg, Grandits, Nilima R, Mosaly, Andrew M, Vekstein, Ralph, Rogers, Fadi, Shehadeh, Matthew, Kaczynski, Evangelia K, Mylona, Konstantinos N, Syrigos, Vasiliki, Rapti, David C, Lye, Diong Shiau, Hui, Lindsay, Leither, Kirk U, Knowlton, Mamta K, Jain, Rubria, Marines-Price, Alice, Osuji, J Scott, Overcash, Ioannis, Kalomenidis, Zafeiria, Barmparessou, Michael, Waters, Karla, Zepeda, Peter, Chen, Sam, Torbati, Francis, Kiweewa, Nicholus, Sebudde, Eyad, Almasri, Alyssa, Hughes, Sanjay R, Bhagani, Alison, Rodger, Uriel, Sandkovsky, Robert L, Gottlieb, Eriobu, Nnakelu, Barbara, Trautner, Vidya, Menon, Joseph, Lutaakome, Michael, Matthay, Philip, Robinson, Konstantinos, Protopapas, Nikolaos, Koulouris, Ivan, Kimuli, Amiran, Baduashvili, Dominique L, Braun, Huldrych F, Günthard, Srikanth, Ramachandruni, Robert, Kidega, Kami, Kim, Timothy J, Hatlen, Andrew N, Phillips, Daniel D, Murray, Tomas O, Jensen, Maria L, Padilla, Evan X, Accardi, Katy, Shaw-Saliba, Robin L, Dewar, Marc, Teitelbaum, Ven, Natarajan, Sylvain, Laverdure, Helene C, Highbarger, M Tauseef, Rehman, Susan, Vogel, David, Vallée, Page, Crew, Negin, Atri, Adam J, Schechner, Sarah, Pett, Fleur, Hudson, Jonathan, Badrock, Giota, Touloumi, Samuel M, Brown, Wesley H, Self, Crystal M, North, Adit A, Ginde, Christina C, Chang, Anthony, Kelleher, Stephanie, Nagy-Agren, Shikha, Vasudeva, David, Looney, Hien H, Nguyen, Adriana, Sánchez, Amy C, Weintrob, Birgit, Grund, Shweta, Sharma, Cavan S, Reilly, Roger, Paredes, Agnieszka, Bednarska, Norman P, Gerry, Abdel G, Babiker, Victoria J, Davey, Annetine C, Gelijns, Elizabeth S, Higgs, Virginia, Kan, Gail, Matthews, B Taylor, Thompson, Philippe, Legenne, Richa, Chandra, H Clifford, Lane, James D, Neaton, Richard, Williams
Publikováno v:
ACTIV-3/TICO Study Group*, Nielsen, H, Thisted, R K, Petersen, K T & Juhl, M R 2022, ' Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial ', Annals of Internal Medicine, vol. 175, no. 9, pp. 1266-1274 . https://doi.org/10.7326/M22-1503
BACKGROUND: Ensovibep (MP0420) is a designed ankyrin repeat protein, a novel class of engineered proteins, under investigation as a treatment of SARS-CoV-2 infection. OBJECTIVE: To investigate if ensovibep, in addition to remdesivir and other standar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d142eddc0f692abd7c33d99b51bb4e
https://vbn.aau.dk/da/publications/828dfc6c-d4d0-47b8-a749-9cc4901459a8
https://vbn.aau.dk/da/publications/828dfc6c-d4d0-47b8-a749-9cc4901459a8
Autor:
Djeneba Dabitao, Kathryn Shaw-Saliba, Drissa S. Konate, Helene C. Highbarger, Perrine Lallemand, Ibrahim Sanogo, Tauseef Rehman, Mamadou Wague, Nadie Coulibaly, Bourahima Kone, Bocar Baya, Seidina A.S. Diakite, Seydou Samake, Esther Akpa, Moctar Tounkara, Sylvain Laverdure, Seydou Doumbia, H. Clifford Lane, Mahamadou Diakite, Robin L. Dewar
Publikováno v:
Journal of Immunological Methods. 517:113488
Autor:
Robin L. Dewar, Perrine Lallemand, Suteeraporn Pinyakorn, Donn J Colby, Jintanat Ananworanich, Tippawan Pankam, Catherine W. Cai, Mark de Souza, Adam Rupert, Sandhya Vasan, Irini Sereti, Supanit Pattanachaiwit, Eugene Kroon, Helene C Highbarger, Sasiwimol Ubolyam
Publikováno v:
Open forum infectious diseases, 7(9):ofaa383. Oxford University Press
Open Forum Infect Dis
Open Forum Infect Dis
Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dime
Autor:
Helene C Highbarger, Dwight V. Nissley, Xiaofeng Chen, Jennifer L. Troyer, Xiaoli Jiao, Liang Ma, Tomozumi Imamichi, Dun Liang, Thomas Skelly, Xin Zheng, Bao Tran, Robert M. Stephens, Richard A. Lempicki, Robin L. Dewar, Min Kang Jiang, Castle Raley, H. Clifford Lane, Alice Pau, Da-Wei Huang, Brad T. Sherman, M Tauseef Rehman
Publikováno v:
Journal of data mining in genomics & proteomics
Development of HIV-1 drug resistance mutations (HDRMs) is one of the major reasons for the clinical failure of antiretroviral therapy. Treatment success rates can be improved by applying personalized anti-HIV regimens based on a patient’s HDRM prof
Autor:
Helene C. Highbarger, Zonghui Hu, Alice K. Pau, Dean Follmann, Harsha Somaroo, Robin L. Dewar, Judith N. Dlamini
Publikováno v:
Pharmacotherapy. 31:158-163
Study Objective. To evaluate the effect of a previous single dose of nevirapine given to prevent mother-to-child transmission of human immunodeficiency virus (HIV) on virologic and immunologic measures after 6 months of an antiretroviral regimen cont
Autor:
Michael A. Polis, Catherine Rehm, Michael A. Proschan, Avidan U. Neumann, Veronique Nussenblatt, Tom Imamichi, Helene C. Highbarger, Robin L. Dewar, Henry Masur, J. Yang, Shyam Kottilil, Richard A. Lempicki, Terry Brann, Chad Koratich, Mary McLaughlin
Publikováno v:
AIDS research and human retroviruses. 23(11)
Viral breakthroughs (VB), defined as having detectable HCV VL while on anti-HCV therapy after achieving maximal suppression, have not yet been characterized with the use of PEG-IFN in HIV/HCV-coinfected patients. We evaluated possible mechanisms for
Autor:
M. B. Vasudevachari, Michael A. Polis, Robin L. Dewar, Julia A. Metcalf, Shyam Kottilil, Zonghui Hu, Helene C. Highbarger, H. Clifford Lane
Publikováno v:
Journal of clinical microbiology. 45(9)
This study compared two commercially available assays for the measurement of hepatitis C virus (HCV) RNA levels, the Bayer HCV RNA (version 3.0) branched DNA assay and the Abbott HCV analyte-specific reagent real-time PCR assay, to assess their quant
Autor:
H. Clifford Lane, Akram S. Shah, Julia A. Metcalf, Helene C. Highbarger, W. Gregory Alvord, Min Kang Jiang, Robin L. Dewar
Publikováno v:
Journal of clinical microbiology. 37(11)
This study evaluated correlation and agreement between version 3 of the Quantiplex human immunodeficiency virus type 1 (HIV-1) RNA assay (v3 branched DNA [bDNA]) and a sensitized Amplicor HIV-1 Monitor assay (reverse transcription [RT]-PCR) for the m
Autor:
Brad Wood, Shyamasundaran Kottilil, Helene C. Highbarger, Michael A. Proschan, Susan Wroblewski, Wenjuan Gu, Laura Heytens, Anita Kohli, Amy Nelson, Rachel Silk, Colleen Kotb, Mani Subramanian, Michael C. Sneller, Richard Kwan, Yu-Jin Lee, John G. McHutchison, Xiao Zhang, Dawn Fishbein, A. Osinusi, Eva Herrmann, David E. Kleiner, Geb Teferi, Dimitra Bon, Bhavana Shivakumar, Eric G. Meissner, Anthony S. Fauci, Jose Chavez, William T. Symonds, Rohit Talwani, Robin Dewar, Lisa Barrett, Michael A. Polis, Henry Masur
Publikováno v:
JAMA. 310:804
The efficacy of directly acting antiviral agents in interferon-free regimens for the treatment of chronic hepatitis C infections needs to be evaluated in different populations.To determine the efficacy and safety of sofosbuvir with weight-based or lo