Výsledky vyhledávání - "Helene Bensoussan"

Cerebral cortex and hippocampus respond differently after post-natal exposure to uranium

Autor: Olivia Delissen, Isabelle Dublineau, Philippe Voisin, Philippe Lestaevel, Claire-Marie Vacher, Mohammed Taouis, Helene Bensoussan, B. Dhieux

Publikováno v: Journal of Toxicological Sciences 5 (38), 803-811. (2013)
The Journal of Toxicological Sciences
The Journal of Toxicological Sciences, Japanese Society of Toxicology, 2013, 38 (5), pp.803-811
The Journal of Toxicological Sciences, Japanese Society of Toxicology, 2012, 38 (5), pp.803-11. ⟨10.2131/jts.38.803⟩

International audience; The central nervous system (CNS) is known to be sensitive to pollutants during its development. Uranium (U) is a heavy metal that occurs naturally in the environment as a component of the earth's crust, and populations may the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4031d678c8c34aa7777349ed4f144347
https://doi.org/10.2131/jts.38.803

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Distribution of Soluble Uranium in the Nuclear Cell Compartment at Subtoxic Concentrations

Autor: Yann Gueguen, David Suhard, Line Grandcolas, Isabelle Dublineau, Mohammed Taouis, François Rebière, Philippe Lestaevel, Christine Tessier, Marc Pallardy, Helene Bensoussan, Caroline Rouas

Publikováno v: Chemical Research in Toxicology
Chemical Research in Toxicology, American Chemical Society, 2010, 23 (12), pp.1883-9. ⟨10.1021/tx100168c⟩

International audience; Uranium is naturally found in the environment, and its extensive use results in an increased risk of human exposure. Kidney cells have mainly been used as in vitro models to study effects of uranium exposure, and very little a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865608af9438d1aba14094e33f081616
https://doi.org/10.1021/tx100168c

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Césium 137 : propriétés et effets biologiques après contamination interne

Autor: Yann Gueguen, Jean-René Jourdain, R. Racine, Helene Bensoussan, Philippe Lestaevel, Patrick Gourmelon, Maâmar Souidi, Isabelle Dublineau, Jean-Marc Bertho, Caroline Rouas

Publikováno v: Médecine Nucléaire. 34:108-118

Resume Le cesium 137 (137Cs) est un radionucleide retrouve dans l’environnement suite aux essais aeriens des armes nucleaires et aux accidents survenus dans des centrales nucleaires comme a Tchernobyl en 1986. Les consequences sanitaires d’une ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a677b8485bfb48dc7aac5a286bfb2fd2
https://doi.org/10.1016/j.mednuc.2009.12.003

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Influence of environmental enrichment and depleted uranium on behaviour, cholesterol and acetylcholine in apolipoprotein E-deficient mice

Autor: P. Voisin, Olivia Delissen, Jocelyne Aigueperse, Maâmar Souidi, Line Manens, R. Racine, F. Airault, Helene Bensoussan, B. Dhieux, Philippe Lestaevel

Publikováno v: Journal of Molecular Neuroscience
Journal of Molecular Neuroscience, Humana Press, 2014, 53 (3), pp.469-479. ⟨10.1007/s12031-013-0038-0⟩

International audience; Alzheimer's disease is associated with genetic risk factors, of which the apolipoprotein E (ApoE) is the most prevalent, and is affected by environmental factors that include education early in life and exposure to metals. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac50f2e7bc58166e67415c05bbf901b
https://pubmed.ncbi.nlm.nih.gov/23749703

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Transcriptomic effects of depleted uranium on acetylcholine and cholesterol metabolisms in Alzheimer's disease model

Autor: Philippe Lestaevel, Patrick Gourmelon, Maâmar Souidi, R. Racine, Fabrice Airault, Helene Bensoussan

Publikováno v: Comptes Rendus Biologies
Comptes Rendus Biologies, Elsevier, 2011, 334, pp.85--90. ⟨10.1016/j.crvi.2010.12.004⟩

Some heavy metals, or aluminium, could participate in the development of Alzheimer disease (AD). Depleted uranium (DU), another heavy metal, modulates the cholinergic system and the cholesterol metabolism in the brain of rats, but without neurologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd3b486e6ffa6741305ace167c5730a
https://hal.archives-ouvertes.fr/hal-02924828

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Heavy metal uranium affects the brain cholinergic system in rat following sub-chronic and chronic exposure

Autor: Isabelle Dublineau, Line Grancolas, Claire-Marie Vacher, Philippe Lestaevel, Bernadette Dhieux-Lestaevel, Helene Bensoussan, Philippe Voisin, Mohammed Taouis, Olivia Delissen, Patrick Gourmelon

Publikováno v: Toxicology
Toxicology, Elsevier, 2009, 261 (1-2), pp.59-67. ⟨10.1016/j.tox.2009.04.054⟩

International audience; Uranium is a heavy metal naturally present in the environment that may be chronically ingested by the population. Previous studies have shown that uranium is present in the brain and alters behaviour, notably locomotor activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277f4d1502d90179de4a37e8d3839cec
https://hal.archives-ouvertes.fr/hal-01183362

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Cholinergic system: a new target of uranium after chronic exposure

Autor: P. Voisin, Isabelle Dublineau, Patrick Gourmelon, Helene Bensoussan, Philippe Lestaevel, P. Laloi, Mohammed Taouis, Claire-Marie Vacher

Publikováno v: Radioprotection. 43

Memory, learning and sensorimotor are govern by cerebral cortex which is a cholinergic widespread structure. Previous studies showed that sleep/wake cycle, spatial memory and locomotion were impaired after a chronic exposure to depleted uranium (DU)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62fcf1d057bce35449c2999d1e5d8cbe
https://doi.org/10.1051/radiopro:2008672

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