Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Helene A. Yuen"'
Autor:
Lewis R. Silverman, Weiru Hong, Maher Albitar, Alison L. Hannah, Francis J. Giles, Helene A. Yuen, Jeffrey E. Lancet, Judith E. Karp, Srdan Verstovsek, Julie M. Cherrington, Maureen Cooper, Sharianne G. Louie, Hagop M. Kantarjian, Jorge E. Cortes, Susan O'Brien, Anne Marie O'Farrell, Alison Stopeck
Publikováno v:
Blood. 102:795-801
Increased bone marrow angiogenesis and vascular endothelial growth factor (VEGF) levels are adverse prognostic features in patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDSs). VEGF is a soluble circulating angiogenic molecu
Autor:
Francis J. Giles, Beverly D. Smolich, Kristina A. West, Julie M. Cherrington, Helene A. Yuen, Maher Albitar
Publikováno v:
Blood. 97:1413-1421
SU5416 and SU6668 are potent antiangiogenic small-molecule inhibitors of receptor tyrosine kinases, including those of the vascular endothelial growth factor and platelet-derived growth factor receptor families. The stem cell factor (SCF) receptor, c
Autor:
Anne-Marie, O'Farrell, James M, Foran, Walter, Fiedler, Hubert, Serve, Ron L, Paquette, Maureen A, Cooper, Helene A, Yuen, Sharianne G, Louie, Heidi, Kim, Susan, Nicholas, Michael C, Heinrich, Wolfgang E, Berdel, Carlo, Bello, Mark, Jacobs, Paul, Scigalla, William C, Manning, Stephen, Kelsey, Julie M, Cherrington
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(15)
Obtaining direct and rapid proof of molecular activity in early clinical trials is critical for optimal clinical development of novel targeted therapies. SU11248 is an oral multitargeted kinase inhibitor with selectivity for fms-related tyrosine kina
Autor:
Julie M. Cherrington, Weiru Hong, Beverly Smolich, Anne Marie O'Farrell, Maher Albitar, Alison L. Hannah, Sharianne G. Louie, Alison Stopeck, Helene A. Yuen, Jeffrey E. Lancet, Lewis R. Silverman, Judith E. Karp, Francis J. Giles
Publikováno v:
Leukemia research. 28(7)
Acute myeloid leukemia (AML) is associated with dysregulated hematopoietic cell proliferation and increased bone marrow angiogenesis, each regulated by signaling through receptor tyrosine kinases (RTKs). SU5416 is a small molecule inhibitor of VEGF r