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pro vyhledávání: '"Helena Yin Yee Sim"'
Autor:
Joohyung Lee, Daniel Peter Czech, Helena Yin Yee Sim, Clare L. Parish, Vincent R. Harley, Eric Vilain
Publikováno v:
Journal of Neurochemistry. 122:260-271
The male gender is determined by the sex-determining region on the Y chromosome (SRY) transcription factor. The unexpected action of SRY in the control of voluntary movement in male rodents suggests a role in the regulation of dopamine transmission a
Autor:
Josephine Bowles, Peter J. McClive, Helena Yin Yee Sim, Andrew H. Sinclair, Kevin Christopher Knower, Peter Koopman, Vincent R. Harley
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 1(2)
The study of the mammalian sex-determining pathway has been hampered by the lack of cell culture systems to investigate the underlying molecular relationships between sex-determining genes. Recent approaches using high-throughput genome-wide studies
Autor:
Robin Lovell-Badge, Kevin Christopher Knower, Stefan Bagheri-Fam, Helena Yin Yee Sim, Pascal Bernard, Louisa M. Ludbrook, Sabine Kelly, Vincent R. Harley, Ryohei Sekido
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e17751 (2011)
PLoS ONE, Vol 6, Iss 3, p e17751 (2011)
BackgroundIn human embryogenesis, loss of SRY (sex determining region on Y), SOX9 (SRY-related HMG box 9) or SF1 (steroidogenic factor 1) function causes disorders of sex development (DSD). A defining event of vertebrate sex determination is male-spe