Výsledky vyhledávání - "Helena Tristan"

Synthesis and Affinities for Dopamine (D2) and 5-Hydroxytryptamine (5-HT2A Receptors of 1-(Benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)- piperazines as Cyclic Butyrophenone Derivatives

Autor: Isabel Loza, Angeles Honrubia, Christian F. Masaguer, María L. de Ceballos, Jose Cid, Tomas G-Ferreiro, J. A. Fontenla, Jesus Negreira, J. M. Calleja, E. Ravina, Javier Fueyo, Helena Tristan, Elizabeth Rosa

Publikováno v: Chemical and Pharmaceutical Bulletin. 44:534-541

Starting from benzo- or thienocycloalkaneacetic acids, we have prepared a series of 1-(3-p-fluorobenzoylpropyl)-4-(1-oxo-benzo- or thienocycloalkyl-2-ethyl)piperazines 8a-e containing both semirigid and linear butyrophenones pharmacophores. The affin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc2658860525b7b55f9dd18fe6d44b2
https://doi.org/10.1248/cpb.44.534

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ChemInform Abstract: Synthesis and Affinities for Dopamine (D2) and 5-Hydroxytryptamine (5- HT2A) Receptors of 1-(Benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl) piperazines as Cyclic Butyrophenone Derivatives

Autor: J. Negreira, Helena Tristan, Tomas G-Ferreiro, C. F. Masaguer, I. Loza, A. Honrubia, E. Ravina, M.L. De Ceballos, E. Rosa, J. A. Fontenla, J. Fueyo, José Ángel Cid, J. M. Calleja

Publikováno v: ChemInform. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6853046dfebb8535e73eff3ef317b3a
https://doi.org/10.1002/chin.199634165

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ChemInform Abstract: Butyrophenone Analogues in the Carbazole Series: Synthesis and Determination of Affinities at D2 and 5-HT2A Receptors

Autor: Emilia Rivas, Christian F. Masaguer, José Angel Fontenla, Enrique Raviña, Emilio Formoso, Helena Tristan, M. Isabel Loza

Publikováno v: ChemInform. 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::327c18048f4947e0fab913a066e60db2
https://doi.org/10.1002/chin.199917126

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ChemInform Abstract: Butyrophenone Analogues in the Carbazole Series as Potential Atypical Antipsychotics: Synthesis and Determination of Affinities at D2, 5-HT2A, 5-HT2B and 5-HT2C Receptors

Autor: Christian F. Masaguer, Helena Tristan, José Brea, Enrique Raviña, José Angel Fontenla, María Isabel Loza

Publikováno v: ChemInform. 31

We describe practical and efficient routes for synthesis of 2-aminomethyl-1,2,3,9-tetrahydro-4 H -carbazol-4-ones using the Fischer indole synthesis or palladium-catalysed cyclization methodologies, as well as their affinities for D 2 , 5-HT 2A and 5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0431f2c916f0227294b43ccd3543f2b5
https://doi.org/10.1002/chin.200025121

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Study of the in vivo and in vitro cardiovascular effects of four new analogues of ketanserin: implication of 5-HT2A and alpha1 adrenergic antagonism in their hypotensive effect

Autor: Tomas Garcia-Ferreiro, Francisco Orallo, I. Cadavid, Jpse M. Calleja, C. F. Masaguer, Helena Tristan, Enrique Raviña, María Isabel Loza, Sonia De Francisco

Publikováno v: Biologicalpharmaceutical bulletin. 23(5)

The in vivo and in vitro cardiovascular effects of the novel 5-HT2A/alpha1/H1 antagonist ketanserin analogues QF 0303B, QF 0307B, QF 0311B, QF 0313B were studied in anaesthetized normotensive rats (ANR) and in isolated rubbed rat aorta (IRRA). In ANR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aa420c3f74d0990ae2c15631e04691
https://pubmed.ncbi.nlm.nih.gov/10823664

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Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: synthesis and determination of affinities at D(2), 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

Autor: José Brea, Christian F. Masaguer, María Isabel Loza, Enrique Raviña, Helena Tristan, José Angel Fontenla

Publikováno v: European journal of medicinal chemistry. 35(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce72245a14edb2368439347d82dc008
https://pubmed.ncbi.nlm.nih.gov/10733606

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