Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Helena T A van Tol"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
The presence of cellular fragments in the perivitelline space is a commonly used parameter to determine quality before transfer of in vitro produced (IVP) embryos. However, this parameter is difficult to assess after blastocyst expansion. In this stu
Externí odkaz:
https://doaj.org/article/ebb6f2b5f6294862aa7b8060e0338f3e
Autor:
Marcia A. M. M. Ferraz, Hoon Suk Rho, Daiane Hemerich, Heiko H. W. Henning, Helena T. A. van Tol, Michael Hölker, Urban Besenfelder, Michal Mokry, Peter L. A. M. Vos, Tom A. E. Stout, Séverine Le Gac, Bart M. Gadella
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In vitro culture has detrimental effects on transcriptomes and epigenetic programming of zygotes. Here the authors use microfluidic technology to co-culture bovine oviduct epithelial cells with zygotes and show that the transcriptomes and global meth
Externí odkaz:
https://doaj.org/article/b2189c0b6d4a43509e715b245fc4d76a
Publikováno v:
Cells, Vol 9, Iss 4, p 1016 (2020)
X-chromosome inactivation (XCI) is a developmental process that aims to equalize the dosage of X-linked gene products between XY males and XX females in eutherian mammals. In female mouse embryos, paternal XCI is initiated at the 4-cell stage; howeve
Externí odkaz:
https://doaj.org/article/e5de586d0ac846aa9c855dde5c1e32d4
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199310 (2018)
Chronically high blood glucose concentrations are a characteristic of diabetes mellitus. Maternal diabetes affects the metabolism of early embryos and can cause a delay in development. To mimic maternal diabetes, bovine in vitro fertilization and emb
Externí odkaz:
https://doaj.org/article/373650c094024de9b8f926011bf7851c
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2509
In modern biomedical research, mice have been the mammalian model system of choice to investigate molecular pathways for potential future medical applications. Over the last years, it has become clear that female mice employ an exceptional piRNA path
Autor:
Bas Brinkhof, Helena T A van Tol, Marian J A Groot Koerkamp, Richard W Wubbolts, Henk P Haagsman, Bernard A J Roelen
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172920 (2017)
In mammalian preimplantation development, pluripotent cells are set aside from cells that contribute to extra-embryonic tissues. Although the pluripotent cell population of mouse and human embryos can be cultured as embryonic stem cells, little is kn
Externí odkaz:
https://doaj.org/article/14f5628330f54817ba5c2ffd05a1ebf8
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623794
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72c82214e433d325d2131e70a1df8e2d
https://doi.org/10.1007/978-1-0716-2380-0_5
https://doi.org/10.1007/978-1-0716-2380-0_5
Autor:
Mahdi Mahdipour, Ana Rita Canhoto Leitoguinho, Ricardo A Zacarias Silva, Helena T A van Tol, Tom A E Stout, Gabriela Rodrigues, Bernard A J Roelen
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132591 (2015)
Transforming acidic coiled-coil (TACC) proteins are key players during mitosis via stabilization of the spindle. The roles of TACCs during meiosis are however less clear. We used bovine oocytes to study the expression and function of TACC3 during mei
Externí odkaz:
https://doaj.org/article/a4cf53e072fe4cc58087e1ae882e332f
Publikováno v:
Non-Coding RNA, Vol 3, Iss 1, p 12 (2017)
Cumulus cells play an essential role during oocyte maturation and the acquisition of fertilizability and developmental competence. Micro(mi)RNAs can post-transcriptionally regulate mRNA expression, and we hypothesized that miRNA profiles in cumulus c
Externí odkaz:
https://doaj.org/article/7ad1986398464d59a2fed5ff64b2fb99
Autor:
Kusdiantoro Mohamad, Mia Olsson, Helena T. A. van Tol, Sofia Mikko, Bart H. Vlamings, Göran Andersson, Heriberto Rodríguez-Martínez, Bambang Purwantara, Robert W. Paling, Ben Colenbrander, Johannes A. Lenstra
Publikováno v:
PLoS ONE, Vol 4, Iss 5 (2009)
Externí odkaz:
https://doaj.org/article/ee880c62ca804740ac992791c46d5788