Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Helena Simolin"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75904 (2013)
The ether-lipid precursor sn-1-O-hexadecylglycerol (HG) can be used to compensate for early metabolic defects in ether-lipid biosynthesis. To investigate a possible metabolic link between ether-linked phospholipids and the rest of the cellular lipido
Externí odkaz:
https://doaj.org/article/9847eb1f32fb4d62837cf2af11bf99ad
Autor:
Amos Baruch, Jari Metso, Reijo Laaksonen, Mika Hilvo, Helena Simolin, Matti Jauhiainen, Katariina Öörni, Maija Ruuth
Background and aims: While inhibition of proprotein convertase subtilisin/kexin type 9 (PCSK9) is known to result in dramatic lowering of LDL-cholesterol (LDL-C), it is poorly understood how it affects other lipid species and their metabolism. The ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c146d16980dc6d958478d12b9f91279c
http://hdl.handle.net/10138/300883
http://hdl.handle.net/10138/300883
Autor:
Tore Skotland, Kim Ekroos, Helena Simolin, Maria Lyngaas Torgersen, Tuulia Sylvänne, Tove Irene Klokk, Roger Simm, Simona Kavaliauskiene, Kirsten Sandvig, Anne Berit Dyve Lingelem
Publikováno v:
Biochemical Journal. 470:23-37
2-Deoxy-D-glucose (2DG) is a structural analogue of glucose with well-established applications as an inhibitor of glycolysis and N-glycosylation. Importantly, 2DG has been shown to improve the efficacy of several cancer chemotherapeutic agents in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c120e89f46a5b405d3894d8c03fb4e77
https://doi.org/10.1042/bj20141562
https://doi.org/10.1042/bj20141562
Autor:
Helena Simolin, Santosh Phuyal, Robert G. Parton, Tore Skotland, Andreas Brech, Anders Øverbye, Nina Pettersen Hessvik, Kim Ekroos, Alicia Llorente, Kirsten Sandvig
Publikováno v:
Journal of Biological Chemistry. 290:4225-4237
Exosomes are vesicles released by cells after fusion of multivesicular bodies with the plasma membrane. In this study, we have investigated whether ether lipids affect the release of exosomes in PC-3 cells. To increase the cellular levels of ether li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a918529aa97fe70a41302e8874f1690b
https://doi.org/10.1074/jbc.m114.593962
https://doi.org/10.1074/jbc.m114.593962
Publikováno v:
Analytical and Bioanalytical Chemistry. 407:5091-5099
Lysophospholipids (LPLs) are an essential family of lipids, which serve as bioactive molecules and as precursors and intermediates of the glycerophospholipid and sphingolipid metabolisms. In this work we primarily focused on the subgroup lysoglycerop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f941aeb608ca844066912a176d617a5
https://doi.org/10.1007/s00216-014-8453-9
https://doi.org/10.1007/s00216-014-8453-9
Autor:
Anne Berit Dyve Lingelem, Kirsten Sandvig, Tuulia Sylvänne, Bjørn Spilsberg, Tore Skotland, Kim Ekroos, Roger Simm, Jonas Bergan, Helena Simolin, Toril Lindbäck
Publikováno v:
Cellular and Molecular Life Sciences. 71:4285-4300
Shiga toxin-producing Escherichia coli bacteria cause hemorrhagic colitis and hemolytic uremic syndrome in humans. Currently, only supportive treatment is available for diagnosed patients. We show here that 24-h pretreatment with an ether lipid precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46905cc9e1f7b111fef07a880667d663
https://doi.org/10.1007/s00018-014-1624-1
https://doi.org/10.1007/s00018-014-1624-1
Autor:
Simona Kavaliauskiene, Carl Martin Nymark, Tore Skotland, Helena Simolin, Kirsten Sandvig, Roger Simm, Jonas Bergan, Tuulia Sylvänne, Kim Ekroos
Publikováno v:
Cellular and Molecular Life Sciences. 71:1097-1116
Cell density is one of the extrinsic factors to which cells adapt their physiology when grown in culture. However, little is known about the molecular changes which occur during cell growth and how cellular responses are then modulated. In many cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8b301677b66b24c1de0c05cb1c413e
https://doi.org/10.1007/s00018-013-1441-y
https://doi.org/10.1007/s00018-013-1441-y
Autor:
Helena Simolin, Kirsten Sandvig, Kim Ekroos, Dimple Kauhanen, Alicia Llorente, Tore Skotland, Viktor Berge, Therese Seierstad
Publikováno v:
European journal of cancer (Oxford, England : 1990). 70
Background Exosomes have recently appeared as a novel source of noninvasive cancer biomarkers, since these nanovesicles contain molecules from cancer cells and can be detected in biofluids. We have here investigated the potential use of lipids in uri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a3b15e03039825f81780cc2a7b6700
https://pubmed.ncbi.nlm.nih.gov/27914242
https://pubmed.ncbi.nlm.nih.gov/27914242
Autor:
Maria Lyngaas Torgersen, Kim Ekroos, Tore Skotland, Simona Kavaliauskiene, Tove Irene Klokk, Tuulia Lintonen, Kirsten Sandvig, Anne Berit Dyve Lingelem, Helena Simolin
Publikováno v:
Oncotarget
// Simona Kavaliauskiene 1, 2, 3 , Maria Lyngaas Torgersen 1, 2 , Anne Berit Dyve Lingelem 1, 2 , Tove Irene Klokk 1, 2 , Tuulia Lintonen 4 , Helena Simolin 4 , Kim Ekroos 4 , Tore Skotland 1, 2 , Kirsten Sandvig 1, 2, 3 1 Department of Molecular Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916b5e7faadcd874b478af3cf69fd596
https://pubmed.ncbi.nlm.nih.gov/27829218
https://pubmed.ncbi.nlm.nih.gov/27829218
Autor:
Jarl Hemming, Andrey Pranovich, Kati Uotila, Stefan Willför, Christiane Laine, Helena Simolin, Bodo Saake, Bjarne Holmbom, Juergen Puls, Anna Suurnäkki, Tarja Tamminen
Publikováno v:
Willför, S, Pranovich, A, Tamminen, T, Puls, J, Laine, C, Suurnäkki, A, Saake, B, Uotila, K, Simolin, H, Hemming, J & Holmbom, B 2009, ' Carbohydrate analysis of plant materials with uronic acid-containing polysaccharides : A comparison between different hydrolysis and subsequent chromatographic analytical techniques ', Industrial Crops and Products, vol. 29, no. 2-3, pp. 571-580 . https://doi.org/10.1016/j.indcrop.2008.11.003
Acid hydrolysis, acid methanolysis, and enzymatic hydrolysis were compared for depolymerization of five different plant materials containing uronic acids. The analyzed plant materials were oat spelt, wheat straw, spruce thermomechanical pulp, aspen s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879cb1fa6072406b42fabceff74517e2
https://doi.org/10.1016/j.indcrop.2008.11.003
https://doi.org/10.1016/j.indcrop.2008.11.003