Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Helena Rudnicka"'
Autor:
Andrzej Jasiewicz, Helena Rudnicka, Wojciech Kluźniak, Wojciech Gronwald, Tomasz Kluz, Cezary Cybulski, Anna Jakubowska, Jan Lubiński, Jacek Gronwald
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-5 (2022)
Abstract Background Mutations in BRCA1 and BRCA2 genes are well-established risk factors of breast and ovarian cancer. In our former study, we observed that approximately 6% of unselected ovarian cancer patients in the region of Podkarpacie (South-Ea
Externí odkaz:
https://doaj.org/article/8bb72149f5204bcc8c65fb5e8e223ccd
Autor:
Emilia Rogoża-Janiszewska, Karolina Malińska, Piotr Baszuk, Wojciech Marciniak, Róża Derkacz, Marcin Lener, Anna Jakubowska, Cezary Cybulski, Tomasz Huzarski, Bartłomiej Masojć, Jacek Gronwald, Helena Rudnicka, Andrzej Kram, Magdalena Kiedrowicz, Magdalena Boer, Tadeusz Dębniak, Jan Lubiński
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 991 (2021)
Melanoma is one of the most aggressive human malignancies. The determination of prognostic biomarkers is important for the early detection of recurrence and for the enrollment of the patients into different treatment regimens. Herein, we report the 1
Externí odkaz:
https://doaj.org/article/075224e30cb842b18d893b08a37088c2
Autor:
Tadeusz Dębniak, Rodney J Scott, Bohdan Górski, Bartłomiej Masojć, Andrzej Kram, Romuald Maleszka, Cezary Cybulski, Katarzyna Paszkowska-Szczur, Aniruddh Kashyap, Dawid Murawa, Karolina Malińska, Magdalena Kiedrowicz, Emilia Rogoża-Janiszewska, Helena Rudnicka, Jakub Deptuła, Paweł Domagała, Wojciech Kluźniak, Marcin R Lener, Jan Lubiński
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204768 (2018)
The association of BRCA1/2 mutations with melanoma is not completely determined; the interpretation of variants of unknown significance is also problematic. To evaluate these issues we explored the molecular basis of melanoma risk by performing whole
Externí odkaz:
https://doaj.org/article/4e2f8eeb5828426ebe60e920893c343b
Autor:
Cezary Cybulski, Neda Zamani, Wojciech Kluźniak, Larissa Milano, Dominika Wokołorczyk, Klaudia Stempa, Helena Rudnicka, Shiyu Zhang, Maryam Zadeh, Tomasz Huzarski, Anna Jakubowska, Tadeusz Dębniak, Marcin Lener, Marek Szwiec, Paweł Domagała, Amir Abbas Samani, Steven Narod, Jacek Gronwald, Jean-Yves Masson, Jan Lubiński, Mohammad R. Akbari
Publikováno v:
The American Journal of Human Genetics. 110:648-662
Autor:
Cybulski, Katarzyna Gliniewicz, Wojciech Kluźniak, Dominika Wokołorczyk, Tomasz Huzarski, Klaudia Stempa, Helena Rudnicka, Anna Jakubowska, Marek Szwiec, Joanna Jarkiewicz-Tretyn, Mariusz Naczk, Tomasz Kluz, Tadeusz Dębniak, Jacek Gronwald, Jan Lubiński, Steven A. Narod, Mohammad R. Akbari, Cezary
Publikováno v:
Genes; Volume 14; Issue 7; Pages: 1329
The APOBEC3B gene belongs to a cluster of DNA-editing enzymes on chromosome 22 and encodes an activation-induced cytidine deaminase. A large deletion of APOBEC3B was associated with increased breast cancer risk, but the evidence is inconclusive. To i
Autor:
Helena Rudnicka, Klaudia Stempa, Mariusz Naczk, Wojciech Kluźniak, Karolina Malińska, Cezary Cybulski, Anna Jakubowska, Emilia Rogoża-Janiszewska, Joanna Tomiczek-Szwiec, Piotr Kozlowski, Tomasz Huzarski, Marcin Lener, Katarzyna Gliniewicz, Malwina Suszynska, Tomasz Kluz, Tadeusz Dębniak, Jacek Gronwald, Pawel Domagala, Mohammad R. Akbari, Steven A. Narod, Jan Lubinski, Dominika Wokołorczyk
Publikováno v:
Cancers
Volume 13
Issue 21
Cancers, Vol 13, Iss 5464, p 5464 (2021)
Volume 13
Issue 21
Cancers, Vol 13, Iss 5464, p 5464 (2021)
Simple Summary Current cancer testing gene panels tend to be comprehensive. One of the genes commonly included in the testing panels is BARD1. To establish whether BARD1 mutations predispose to prostate cancer, we sequenced BARD1 in 390 hereditary pr
Autor:
Aniruddh Kashyap, Rodney J. Scott, Emilia Rogoża, Tomasz Gromowski, Karolina Malińska, Bohdan Górski, Rodney A Lea, Andrzej Kram, Jakub Deptuła, Helena Rudnicka, Katarzyna Paszkowska-Szczur, Romuald Maleszka, Jan Lubinski, Cezary Cybulski, Bartłomiej Masojć, Dawid Murawa, Marcin Lener, Tadeusz Dębniak
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Germline mutations within melanoma susceptibility genes are present only in minority of melanoma patients and it is expected that additional genes will be discovered with next generation sequence technology and whole-exome sequencing (WES). M
Autor:
Cezary Cybulski, Magdalena Cechowska, Mohammad R. Akbari, Jacek Gronwald, Aniruddh Kashyap, Marek Szwiec, Joanna Tomiczek-Szwiec, Helena Rudnicka, Wojciech Kluźniak, Steven A. Narod, Maryam Bagherzadeh, Tomasz Huzarski, Anna Jakubowska, Bogna Rusak, Pawel Domagala, Jan Lubinski, Dominika Wokołorczyk, Marcin Lener, Tadeusz Dębniak, Joanna Jarkiewicz-Tretyn, Agata Szymiczek, Klaudia Stempa
Publikováno v:
Breast Cancer Research and Treatment
Background XRCC2 participates in homologous recombination and in DNA repair. XRCC2 has been reported to be a breast cancer susceptibility gene and is now included in several breast cancer susceptibility gene panels. Methods We sequenced XRCC2 in 617
Autor:
Emilia Rogoża-Janiszewska, Jakub Deptuła, Magdalena Kiedrowicz, Rodney J. Scott, Tadeusz Dębniak, Andrzej Kram, Pawel Domagala, Jolanta Hybiak, Magdalena Boer, Helena Rudnicka, Aniruddh Kashyap, Bartłomiej Masojć, Bohdan Górski, Cezary Cybulski, Karolina Malińska, Jan Lubinski
Publikováno v:
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 29(6)
Evaluation of the prevalence of POT1, ACD, and TERF2IP mutations among Polish melanoma patients. A cohort of 60 patients from melanoma-prone families, 1500 unselected cases and 1500 controls were genotyped. Methodology included Sanger sequencing, in-
Autor:
Beata Kozak-Klonowska, Tomasz Byrski, Jan Lubinski, Tomasz Huzarski, Andrzej Pławski, Magdalena Kuświk, Monika Siołek, E. Kilar, Katarzyna Golebiewska, Pawel Borun, Rodney J. Scott, Raewyn Billings, Helena Rudnicka, Dagmara Dymerska, Marek Szwiec, Grzegorz Kurzawski
Publikováno v:
Clinical Genetics. 92:649-653
It is well known that founder mutations associated with cancer risk have useful implications for molecular diagnostics. We report the presence of a founder mutation in EPCAM involved in the etiology of Lynch syndrome (LS). The mutation extends nearly