Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Helena Pillich"'
Autor:
Renate Frantz, Lisa Teubner, Tilman Schultze, Luigi La Pietra, Christin Müller, Konrad Gwozdzinski, Helena Pillich, Torsten Hain, Michaela Weber-Gerlach, Georgios-Dimitrios Panagiotidis, Ahmed Mostafa, Friedemann Weber, Manfred Rohde, Stephan Pleschka, Trinad Chakraborty, Mobarak Abu Mraheil
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Cellular sensing of bacterial RNA is increasingly recognized as a determinant of host-pathogen interactions. The intracellular pathogen Listeria monocytogenes induces high levels of type I interferons (alpha/beta interferons [IFN-α/β]) to
Externí odkaz:
https://doaj.org/article/07b84c71fa274bd1a66c3743af524a09
Autor:
Istvan Czikora, Abdel A. Alli, Supriya Sridhar, Michael A. Matthay, Helena Pillich, Martina Hudel, Besim Berisha, Boris Gorshkov, Maritza J. Romero, Joyce Gonzales, Guangyu Wu, Yuqing Huo, Yunchao Su, Alexander D. Verin, David Fulton, Trinad Chakraborty, Douglas C. Eaton, Rudolf Lucas
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
BackgroundStreptococcus pneumoniae is a major etiologic agent of bacterial pneumonia. Autolysis and antibiotic-mediated lysis of pneumococci induce release of the pore-forming toxin, pneumolysin (PLY), their major virulence factor, which is a promine
Externí odkaz:
https://doaj.org/article/e00463dfbf08482284ebe0f2bdc7fe4c
Autor:
Martin Leustik, Maritza Romero, Helena Pillich, Norman L. Block, Ferenc G. Rick, Jonathan Lawson, Alexander Verin, Aluya Oseghale, Umapathy Siddaramappa, Boris Gorshkov, Evgeny Zemskov, Supriya Sridhar, Istvan Czikora, Rudolf Lucas, Andrew V. Schally, Trinad Chakraborty
Publikováno v:
Toxins, Vol 5, Iss 7, Pp 1244-1260 (2013)
Severe pneumonia is the main single cause of death worldwide in children under five years of age. The main etiological agent of pneumonia is the G+ bacterium Streptococcus pneumoniae, which accounts for up to 45% of all cases. Intriguingly, patients
Externí odkaz:
https://doaj.org/article/f087281299e04b3983ec7d671837bb53
Autor:
Guang Yang, Helena Pillich, Richard White, Istvan Czikora, Isabelle Pochic, Qiang Yue, Martina Hudel, Boris Gorshkov, Alexander Verin, Supriya Sridhar, Carlos M. Isales, Douglas C. Eaton, Jürg Hamacher, Trinad Chakraborty, Rudolf Lucas
Publikováno v:
Toxins, Vol 10, Iss 2, p 79 (2018)
Pulmonary permeability edema is characterized by reduced alveolar Na+ uptake capacity and capillary barrier dysfunction and is a potentially lethal complication of listeriosis. Apical Na+ uptake is mainly mediated by the epithelial sodium channel (EN
Externí odkaz:
https://doaj.org/article/d35feedfab884280ae3e69a7a96bab05
Autor:
Madhu Puri, Luigi La Pietra, Mobarak Abu Mraheil, Rudolf Lucas, Trinad Chakraborty, Helena Pillich
Publikováno v:
Toxins, Vol 9, Iss 9, p 273 (2017)
Autophagy, a well-established defense mechanism, enables the elimination of intracellular pathogens including Listeria monocytogenes. Host cell recognition results in ubiquitination of L. monocytogenes and interaction with autophagy adaptors p62/SQST
Externí odkaz:
https://doaj.org/article/4184bf7596184511b75f1e90bb6be684
Autor:
Besim Berisha, Günter Lochnit, Helena Pillich, Saša Aden, Alexander Perniss, Luigi La Pietra, Amir Rafiq, Gregor Anderluh, Mobarak Abu Mraheil, Martina Hudel, Trinad Chakraborty, Vesna Hodnik
Publikováno v:
The Journal of Infectious Diseases. 222:1505-1516
BackgroundBacterial toxins disrupt plasma membrane integrity with multitudinous effects on host cells. The secreted pore-forming toxin listeriolysin O (LLO) of the intracellular pathogen Listeria monocytogenes promotes egress of the bacteria from vac
Autor:
Asparouh I. Iliev, Timothy J. Mitchell, Helena Pillich, Jana Maurer, Trinad Chakraborty, Sabrina Hupp
Publikováno v:
Scientific Reports
Maurer, Jana; Hupp, Sabrina; Pillich, Helena; Mitchell, Timothy J; Chakraborty, Trinad; Iliev, Asparouh I (2018). Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O. Scientific Reports, 8(1), p. 15846. Nature Publishing Group 10.1038/s41598-018-34031-4
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Maurer, Jana; Hupp, Sabrina; Pillich, Helena; Mitchell, Timothy J; Chakraborty, Trinad; Iliev, Asparouh I (2018). Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O. Scientific Reports, 8(1), p. 15846. Nature Publishing Group 10.1038/s41598-018-34031-4
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
The lytic capacity of cholesterol-dependent cytolysins is enhanced in the extracellular calcium-free environment through a combination of limited membrane repair and diminished membrane toxin removal. For a typical neurotoxin of the group, pneumolysi
Publikováno v:
Infectious Diseases and Your Health ISBN: 9789811315763
Bacterial infections caused by pathogenic bacteria, like tuberculosis by Mycobacterium tuberculosis, listeriosis by Listeria monocytogenes, and gastroenteritis by Salmonella typhimurium, are on the rise. With the increase in pathogen resistance to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27267a746d2109b2393045b08e0a2fa
https://doi.org/10.1007/978-981-13-1577-0_10
https://doi.org/10.1007/978-981-13-1577-0_10
Autor:
Trinad Chakraborty, Alexander D. Verin, Qiang Yue, Richard E. White, Guang Yang, Martina Hudel, Isabelle Pochic, Istvan Czikora, Helena Pillich, Jürg Hamacher, Douglas C. Eaton, Rudolf Lucas, Boris A. Gorshkov, Supriya Sridhar, Carlos M. Isales
Publikováno v:
Toxins
Toxins, Vol 10, Iss 2, p 79 (2018)
Toxins; Volume 10; Issue 2; Pages: 79
Toxins, Vol 10, Iss 2, p 79 (2018)
Toxins; Volume 10; Issue 2; Pages: 79
Pulmonary permeability edema is characterized by reduced alveolar Na⁺ uptake capacity and capillary barrier dysfunction and is a potentially lethal complication of listeriosis. Apical Na⁺ uptake is mainly mediated by the epithelial sodium channel
Publikováno v:
Future Microbiology. 10:583-597
ABSTRACT Listeria monocytogenes is a facultative intracellular bacterium causing listeriosis, a food-borne infection with a high mortality rate. The mechanisms and the role of cells and tissular components in generating protective adaptive immune res