Liver injury in non-alcoholic fatty liver disease is associated with urea cycle enzyme dysregulation

Autor: Rocío Gallego-Durán, Javier Ampuero, Helena Pastor-Ramírez, Leticia Álvarez-Amor, Jose Antonio del Campo, Douglas Maya-Miles, Rocío Montero-Vallejo, Antonio Cárdenas-García, Mª Jesús Pareja, Sheila Gato-Zambrano, Raquel Millán, María del Carmen Rico, Amparo Luque-Sierra, Antonio Gil-Gómez, Ángela Rojas, Rocío Muñoz-Hernández, María García-Lozano, Rocío Aller, Raúl J. Andrade, Carmelo García-Monzón, Fausto Andreola, Francisco Martín, Rajiv Jalan, Manuel Romero-Gómez

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract The main aim was to evaluate changes in urea cycle enzymes in NAFLD patients and in two preclinical animal models mimicking this entity. Seventeen liver specimens from NAFLD patients were included for immunohistochemistry and gene expression

Externí odkaz: https://doaj.org/article/6b0034b1492945a5bad81e9db024ea51

LPAC syndrome associated with deletion of the full exon 4 in a ABCB4 genetic mutation in a patient with hepatitis C

Autor: Blanca Fombuena, Javier Ampuero, Luis Álvarez, Reyes Aparcero, Rocío Llorca, Raquel Millán, Helena Pastor-Ramírez, Sara Andueza, Veronique Barbu, Manuel Romero-Gómez

Publikováno v: Revista Espanola de Enfermedades Digestivas, Vol 106, Iss 8, Pp 544-547 (2014)

Low-phospholipid-associated cholelithiasis syndrome (LPAC) is associated with ABCB4 genetic mutation. ABCB4 encodes MDR3 protein, involved in biliary phosphatidylcholine excretion. Higher prevalence in women, biliary symptoms in young adults and urso

Externí odkaz: https://doaj.org/article/c34317a8e7504ee2b24acb77de0f679c

Ivermectin acute administration impaired the spermatogenesis and spermiogenesis of adult rats

Autor: Cordeiro, Flora, Gonçalves, Vagner, Jr, Moreira, Natalia, Slobodticov, João Iosif, de Andrade Galvão, Nathalia, de Souza Spinosa, Helenice, Bonamin, Leoni Villano, Bondan, Eduardo Fernandes, Ciscato, Claudia Helena Pastor, Barbosa, Cláudia Maria, Bernardi, Maria Martha

Publikováno v: In Research in Veterinary Science April 2018 117:178-186

Risk factors associated to NAFLD-related advanced fibrosis in patients with normal ALT levels

Autor: Javier Ampuero, Rocío Aller, Rocío Gallego-Durán, Javier Crespo, José Luis Calleja Panero, Carmelo García-Monzón, Judith Gómez-Camarero, Juan Caballería, Oreste Lo Iacono, Rafael Bañares, Francisco Javier Garcia-Samaniego Rey, Agustin Albillos, Rubén Francés, Conrado Fernández-Rodríguez, Moises Diago, German Soriano, Raul J. Andrade, Raquel Latorre Martínez, Francisco Jorquera, Rosa Ma Morillas, Desamparados Escudero-García, Pamela Estevez, Manuel Hernandez-Guerra, Salvador Augustin, Helena Pastor, Jesus M. Banales, Patricia Aspichueta, Salvador Benlloch, Jose Miguel Rosales Zabal, Javier Salmerón, Juan Turnés, Manuel Romero Gomez

Publikováno v: Journal of Hepatology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb438b74de23defde791a754d3adbd6f
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4388

Oxidized low-density lipoprotein antibodies/high-density lipoprotein cholesterol ratio is linked to advanced non-alcoholic fatty liver disease lean patients

Autor: Manuel Romero-Gómez, José A Del Campo, María Carmen Rico, Isidora Ranchal, Javier Ampuero, Rocío Gallego-Durán, Raúl J. Andrade, Luis Pastor, Carmelo García-Monzón, Helena Pastor-Ramírez, María Jesús Pareja, Rocío Picón

Publikováno v: Journal of Gastroenterology and Hepatology. 31:1611-1618

BACKGROUND AND AIM A small but significant proportion of patients with normal body mass index show non-alcoholic fatty liver disease (NAFLD). Oxidized low-density lipoprotein (LDL) is a powerful immunogenic molecule, which causes oxidative stress and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbe449968dd10d362d4a680467ae2b6a
https://doi.org/10.1111/jgh.13335