Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Helena Pópulo"'
Autor:
Manuel António Costa Campos, António Fernandes Massa, Paulo Varela, Ana Moreira, Agostinho Sanches, Helena Pópulo, Paula Soares, Armando Baptista
Publikováno v:
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, Vol 76, Iss 3 (2018)
Introdução: O carcinoma espinocelular cutâneo é o segundo cancro cutâneo mais comum e a sua incidência tem crescido. O objetivo do nosso estudo foi realizar uma análise descritiva e analítica dos carcinoma espinocelular cutâneo excisados no
Externí odkaz:
https://doaj.org/article/6439048ae85342278dd14b2fe23b7b2c
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180392 (2017)
SDHD promoter mutations were reported in 4-10% of cutaneous melanomas. The advanced clinico-pathological and patient survival association with SDHD mutation and/or expression in cutaneous melanoma remains controversial.To evaluate the presence of SDH
Externí odkaz:
https://doaj.org/article/2733857bad254fbea23e878259f863cd
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 2, Pp 1886-1918 (2012)
The conserved serine/threonine kinase mTOR (the mammalian target of rapamycin), a downstream effector of the PI3K/AKT pathway, forms two distinct multiprotein complexes: mTORC1 and mTORC2. mTORC1 is sensitive to rapamycin, activates S6K1 and 4EBP1, w
Externí odkaz:
https://doaj.org/article/0d6eeaf7ae004f91bfc9942c7d923bac
Autor:
André Ferreira-da-Silva, Cristina Valacca, Elisabete Rios, Helena Pópulo, Paula Soares, Manuel Sobrinho-Simões, Luca Scorrano, Valdemar Máximo, Silvia Campello
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122308 (2015)
Oncocytic cell tumors are characterized by the accumulation of morphologically abnormal mitochondria in their cells, suggesting a role for abnormal mitochondrial biogenesis in oncocytic cell transformation. Little is known about the reason for the dy
Externí odkaz:
https://doaj.org/article/266e04ec1538447d8a7174356265d291
Autor:
Helena Pópulo, Sandra Tavares, Alexandra Faustino, Joana B. Nunes, José Manuel Lopes, Paula Soares
Publikováno v:
PeerJ, Vol 1, p e104 (2013)
Somatic mutations in GNAQ gene were described as being the main oncogenic activation in uveal melanomas, whereas mutations in BRAF gene have been described as a key genetic alteration that contributes to skin melanoma development. We have previously
Externí odkaz:
https://doaj.org/article/d5da14327fa44e96b654aaf38428c356
Autor:
Maria R. Verdelho, Simão Gonçalves, Luisa Gonçalves, Catarina Costa, José M. Lopes, Margarida M. V. Coelho, Alexandre João, Paula Soares, Helena Pópulo, Catarina Barata
Publikováno v:
Artificial Intelligence over Infrared Images for Medical Applications and Medical Image Assisted Biomarker Discovery ISBN: 9783031196591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcb09e9762759d690eea0ad5701734d6
https://doi.org/10.1007/978-3-031-19660-7_18
https://doi.org/10.1007/978-3-031-19660-7_18
Autor:
José Manuel Lopes, Francisco Vitorino Martins, Maria Isabel Andrade, Helena Pópulo, Paula Soares, Margarida Sá Fernandes, César Martins
Publikováno v:
Dermatology. 238:507-516
Background: While BRAF mutations seem important for early melanomagenesis, mutations in the TERT promoter (TERTp) are related to metastasis. Yet, in conventional melanoma management, risk stratification does not depend on molecular biomarkers that ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62dcd2a313b7df383f1d9e178838ed08
https://doi.org/10.1159/000518219
https://doi.org/10.1159/000518219
Autor:
Bruno Nunes, Helena Pópulo, José Manuel Lopes, Marta Reis, Gilvan Nascimento, Ana Giselia Nascimento, Janaína Fernandes, Manuel Faria, Denise Pires de Carvalho, Paula Soares, Leandro Miranda-Alves
Publikováno v:
Genes; Volume 13; Issue 4; Pages: 674
Gap junction intercellular communication (GJIC) is considered a key mechanism in the regulation of tissue homeostasis. GJIC structures are organized in two transmembrane channels, with each channel formed by connexins (Cxs). GJIC and Cxs expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9d006f8a456f0701ee0b052f6f43fe
https://pubmed.ncbi.nlm.nih.gov/35456480
https://pubmed.ncbi.nlm.nih.gov/35456480
Autor:
Maria R. Verdelho, Simão Gonçalves, Luisa Gonçalves, Catarina Costa, José M. Lopes, Margarida M. V. Coelho, Alexandre João, Paula Soares, Helena Pópulo, Catarina Barata
Publikováno v:
Artificial Intelligence over Infrared Images for Medical Applications and Medical Image Assisted Biomarker Discovery ISBN: 9783031196591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f85d5c28fd8113dc8fc48128f8a63c7
https://doi.org/10.1007/978-3-031-19660-7_17
https://doi.org/10.1007/978-3-031-19660-7_17
Publikováno v:
Journal of Experimental Pharmacology
Helena Pópulo,1– 3 Beatriz Domingues,1,2 Cristina Sampaio,1,2 José Manuel Lopes,1– 4 Paula Soares1– 3 1Institute of Molecular Pathology and Immunology, IPATIMUP, University of Porto, Porto, Portugal; 2Instituto de Investigação e Inovação
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5411129069e62000f68f874469b703d6
https://www.dovepress.com/combinatorial-therapies-to-overcome-brafmek-inhibitors-resistance-in-m-peer-reviewed-fulltext-article-JEP
https://www.dovepress.com/combinatorial-therapies-to-overcome-brafmek-inhibitors-resistance-in-m-peer-reviewed-fulltext-article-JEP