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pro vyhledávání: '"Helena Olbertová"'
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Autor:
Helena Olbertova, Karla Plevova, Sarka Pavlova, Jitka Malcikova, Jana Kotaskova, Kamila Stranska, Michaela Spunarova, Martin Trbusek, Veronika Navrkalova, Barbara Dvorackova, Nikola Tom, Karol Pal, Marie Jarosova, Yvona Brychtova, Anna Panovska, Michael Doubek, Sarka Pospisilova
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Telomeres are protective structures at chromosome ends which shorten gradually with increasing age. In chronic lymphocytic leukemia (CLL), short telomeres have been associated with unfavorable disease outcome, but the link between
Externí odkaz:
https://doaj.org/article/62c7fe3bce37456bb78f5e4434870ef7
Publikováno v:
Biomedical Papers, Vol 163, Iss 1, Pp 1-7 (2019)
Telomeres are repetitive DNA sequences protecting physical ends of linear chromosomes against degradation and end-to-end chromosomal fusion. Telomeres shorten with each cell division, which regulates the cellular lifespan in somatic cells and limits
Externí odkaz:
https://doaj.org/article/9fbc4b49a50b4c7f99290c7f5ef371fb
Publikováno v:
Biomedical Papers, Vol 163, Iss 1, Pp 1-7 (2019)
Telomeres are repetitive DNA sequences protecting physical ends of linear chromosomes against degradation and end-to-end chromosomal fusion. Telomeres shorten with each cell division, which regulates the cellular lifespan in somatic cells and limits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e304d0b6feb37c6bfc81e534fc6d9b4c
https://doi.org/10.5507/bp.2018.084
https://doi.org/10.5507/bp.2018.084