Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Helena Montanuy"'
Autor:
Helena Montanuy, Cristina Camps-Fajol, Jordi Carreras-Puigvert, Maria Häggblad, Bo Lundgren, Miriam Aza-Carmona, Thomas Helleday, Jordi Minguillón, Jordi Surrallés
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background Fanconi anemia is a rare disease clinically characterized by malformations, bone marrow failure and an increased risk of solid tumors and hematologic malignancies. The only therapies available are hematopoietic stem cell transplan
Externí odkaz:
https://doaj.org/article/64abf667360445cfaf72bee11ee1388b
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Purpose:Fanconi anemia rare disease is characterized by bone marrow failure and a high predisposition to solid tumors, especially head and neck squamous cell carcinoma (HNSCC). Patients with Fanconi anemia with HNSCC are not eligible for conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee4ca94fce39854d8a8c19ce177befa
https://doi.org/10.1158/1078-0432.c.6528209.v1
https://doi.org/10.1158/1078-0432.c.6528209.v1
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Figure S5. FACS gating strategy to analyze white blood cell population in WT and Fanca-deficient mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fb1da527d9bd30cf77bb72d47542ad
https://doi.org/10.1158/1078-0432.22472396.v1
https://doi.org/10.1158/1078-0432.22472396.v1
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Figure S8. Additional data on genotoxicity in blood samples from WT or Fanca-deficient mice, by gefitinib and afatinib treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3369db2027699f48f2214fa08f645f
https://doi.org/10.1158/1078-0432.22472384
https://doi.org/10.1158/1078-0432.22472384
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Figure S2. Additional data on gefitinib and afatinib in vivo mouse xenograft experiments. Weight control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2db48856d858559d6c44dcac662adf
https://doi.org/10.1158/1078-0432.22472405.v1
https://doi.org/10.1158/1078-0432.22472405.v1
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Figure S3. Additional immunohistochemistry images from tumor xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16db51b6803ec762fda547e8f50b20ee
https://doi.org/10.1158/1078-0432.22472402.v1
https://doi.org/10.1158/1078-0432.22472402.v1
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Figure S6. Additional data on gefitinib and afatinib toxicity analysis in WT and Fanca-deficient mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebb439b38e8322c959d5dd21987a1d7
https://doi.org/10.1158/1078-0432.22472390
https://doi.org/10.1158/1078-0432.22472390
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Figure S1. Additional data from high content screening and validation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d920352b094302bf74e0c85116c55ff
https://doi.org/10.1158/1078-0432.22472408
https://doi.org/10.1158/1078-0432.22472408
Autor:
Jordi Surrallés, Jordi Minguillón, Diego Arango, Juan A. Bueren, Thomas Helleday, Jordi Carreras-Puigvert, Adriana Lasa, Enrique Lerma, Alan González, Pau Riera, Carlos Carrascoso-Rubio, Rocío Nieto, Maria José Ramírez, Llorenç Rovirosa, José Antonio Casado, Águeda Martínez-Barriocanal, Helena Montanuy
Supplementary Text
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cea94ebc79e6d7290ff7a1ae8d11f9
https://doi.org/10.1158/1078-0432.22472381.v1
https://doi.org/10.1158/1078-0432.22472381.v1
Autor:
Helena Montanuy, Carlos Carrascoso-Rubio, Pau Riera, Jordi Minguillón, Juan A. Bueren, Adriana Lasa, Jordi Surrallés, Thomas Helleday, Diego Arango, Rocio Nieto, José A. Casado, María José Ramírez, Enrique Lerma, Águeda Martínez-Barriocanal, Alan González, Llorenç Rovirosa, Jordi Carreras-Puigvert
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(12)
Purpose: Fanconi anemia rare disease is characterized by bone marrow failure and a high predisposition to solid tumors, especially head and neck squamous cell carcinoma (HNSCC). Patients with Fanconi anemia with HNSCC are not eligible for conventiona