Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Helena Meyer-Berg"'
Autor:
Eduard H.T.M. Ebberink, Alisa Ruisinger, Markus Nuebel, Helena Meyer-Berg, Irene R.S. Ferreira, Marco Thomann, Albert J.R. Heck
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101293- (2024)
Adeno-associated viruses (AAVs) are gaining traction as delivery vehicles for gene therapy although the molecular understanding of AAV-transgene release is still limited. Typically, the process of viral uncoating is investigated (in vitro) through th
Externí odkaz:
https://doaj.org/article/b6751d5aab234cb4ab56c73d1e7c9680
Autor:
Helena Meyer-Berg, Lucia Zhou Yang, María Pilar de Lucas, Alberto Zambrano, Stephen C. Hyde, Deborah R. Gill
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-6 (2020)
Abstract Gene therapy is being investigated for a range of serious lung diseases, such as cystic fibrosis and emphysema. Recombinant adeno-associated virus (rAAV) is a well-established, safe, viral vector for gene delivery with multiple naturally occ
Externí odkaz:
https://doaj.org/article/cfd60483467343929fab9a7c02913e3f
Autor:
Yue Du, Kamran M Miah, Omar Habib, Helena Meyer-Berg, Catriona C Conway, Mariana A Viegas, Rebecca Dean, Dwiantari Satyapertiwi, Jincun Zhao, Yanqun Wang, Nigel J Temperton, Toby P E Gamlen, Deborah R Gill, Stephen C Hyde
Publikováno v:
Thorax. 77:1229-1236
BackgroundThe COVID-19 pandemic continues to be a worldwide threat and effective antiviral drugs and vaccines are being developed in a joint global effort. However, some elderly and immune-compromised populations are unable to raise an effective immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b3e9155f92e16f44421988c17acda5
https://doi.org/10.1136/thoraxjnl-2021-217650
https://doi.org/10.1136/thoraxjnl-2021-217650
Autor:
Yorrick von Ohlen, Johannes Broichhagen, Natalie R. Johnston, Helena Meyer-Berg, Stephen R. Bloom, Dirk Trauner, David J. Hodson, Guy A. Rutter, Ben Jones
Publikováno v:
Angewandte Chemie. 128:5961-5965
Die allosterische Regulation von G-Protein-gekoppelten Rezeptoren (GPCRs) erhoht deren Arzneimittelspezifitat und ermoglicht so neue therapeutische Ansatze. Dennoch ist die heutige Wirkstoffentwicklung gehemmt, da die allosterische Bindestelle nur un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb31c555a1f9481b962f86ae178d544c
https://doi.org/10.1002/ange.201600957
https://doi.org/10.1002/ange.201600957
Autor:
Anja Hoffmann-Röder, Yorrick von Ohlen, Tom Podewin, Helena Meyer-Berg, Guy A. Rutter, Natalie R. Johnston, Ben Jones, Johannes Broichhagen, Stephen R. Bloom, Dirk Trauner, David J. Hodson
Publikováno v:
Angewandte Chemie. 127:15786-15790
Inkretin-Mimetika sind auf dem besten Weg, sich zu einer tragenden Saule in der Typ-2-Diabetes-Behandlung zu entwickeln. Durch ihre Wirkung auf die Bauchspeicheldruse und das Gehirn verstarken sie die Insulinsekretion, induzieren einen Gewichtsverlus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::967019e00509f4e701ad51172797d2c9
https://doi.org/10.1002/ange.201506384
https://doi.org/10.1002/ange.201506384
Autor:
Johannes, Broichhagen, Natalie R, Johnston, Yorrick, von Ohlen, Helena, Meyer-Berg, Ben J, Jones, Stephen R, Bloom, Guy A, Rutter, Dirk, Trauner, David J, Hodson
Publikováno v:
Angewandte Chemie (International Ed. in English)
Allosteric regulation promises to open up new therapeutic avenues by increasing drug specificity at G‐protein‐coupled receptors (GPCRs). However, drug discovery efforts are at present hampered by an inability to precisely control the allosteric s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50a9c6f5274ecf8dd6af69466de63010
https://pubmed.ncbi.nlm.nih.gov/27059784
https://pubmed.ncbi.nlm.nih.gov/27059784
Autor:
Anja Hoffmann-Röder, Ben Jones, Stephen R. Bloom, Dirk Trauner, Yorrick von Ohlen, Helena Meyer-Berg, David J. Hodson, Tom Podewin, Natalie R. Johnston, Johannes Broichhagen, Guy A. Rutter
Publikováno v:
Angewandte Chemie (International Ed. in English)
Incretin mimetics are set to become a mainstay of type 2 diabetes treatment. By acting on the pancreas and brain, they potentiate insulin secretion and induce weight loss to preserve normoglycemia. Despite this, incretin therapy has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd27b8a9ded784fd50d1ad53f25174b8
http://hdl.handle.net/10044/1/27750
http://hdl.handle.net/10044/1/27750
Autor:
Christina V. Frost, Dirk Trauner, Nicholas H. F. Fine, David J. Hodson, Anja Hoffmann-Röder, Dieter Groneberg, Johannes Broichhagen, Tom Podewin, Andreas Friebe, Julia Ast, Helena Meyer-Berg, Martin Zacharias
Publikováno v:
Chemical Science
The photoswitchable peptidomimetic hormone TOP271 allows the precise optical control of cGMP generation via the receptor-linked enzyme NPR-A in explanted aortic rings and islets of Langerhans.
The optical control over biological function with sm
The optical control over biological function with sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5634299f8802a7ce44b2fa50c76c18c4