Výsledky vyhledávání - "Helena M. Treshalina"

New Poly(3-hydroxybutyrate) Microparticles with Paclitaxel Sustained Release for Intraperitoneal Administration

Autor: V. L. Myshkina, Anton P. Bonartsev, S. G. Yakovlev, Natalia V. Andronova, T.K. Mahina, A.L. Zernov, Galina B. Smirnova, Mikhail S. Kalishjan, I. I. Zharkova, Juliya A. Borisova, Helena M. Treshalina, Konstantin V. Shaitan, Garina A. Bonartseva

Publikováno v: Anti-Cancer Agents in Medicinal Chemistry. 17:434-441

Background: Poly(hydroxyalkanoates) (PHA) have recently attracted increasing attention due to their biodegradability and high biocompatibility, which makes them suitable for the development of new prolong drug formulations. Objective: This study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e40a0a1f2c3d8d3e71434e97e96744
https://doi.org/10.2174/1871520615666160504095433

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Evaluation of the internalization of AFP-containing noncovalent complexes AIMPILA in the rat model of the isolated segment of rat small intestine

Autor: G. B Smirnova, J. R Tcherkassova, Helena M. Treshalina, N. B Andronova, S. A Tsurkan

Publikováno v: Russian Journal of Oncology. 21:308-311

Research is devoted to the study of the ability of the labeled complex «AIMPILA-ACRIDIN» and the test compound «AFP-ACRIDIN» in concentration of 1.0 mkg/ml to internalize in a small intestine. For this purpose there was used the modified techniqu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf2805ad5be0bef9b8e86e5d9d44aa20
https://doi.org/10.18821/1028-9984-2016-21-6-308-311

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Results of transarterial chemoembolization on rats with grafted hepatocellular cancer of liver

Autor: A. Yu Fadeev, M. S Kalish'yan, V. Yu Kosirev, Ju. A Borisova, M. N Yakunina, Helena M. Treshalina, G. B Smirnova, E. R. Virshke, B. I. Dolgushin

Publikováno v: Russian Journal of Oncology. 21:259-263

Modeling of a transarterial chemoembolization (TACE) is carried out on rats (n = 6) with hepatocellular cancer of liver RS1 (Vcp = 4.5 cm3) which has developed in muscles of the leg (i.m.). Sensitivity of a tumor to the single introduction of substan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::835b8b41066a2f199f66363eccd11226
https://doi.org/10.18821/1028-9984-2016-21-5-259-263

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T-Cadherin Expression in Melanoma Cells Stimulates Stromal Cell Recruitment and Invasion by Regulating the Expression of Chemokines, Integrins and Adhesion Molecules

Autor: Veronika Yu. Sysoeva, Kseniya A. Rubina, E. V. Semina, E. I. Surkova, Natalia Kalinina, Helena M Treshalina, Alexei Poliakov, Vsevolod A. Tkachuk

Publikováno v: Cancers
Volume 7
Issue 3
Pages 1349-1370
Cancers; Volume 7; Issue 3; Pages: 1349-1370
Cancers, Vol 7, Iss 3, Pp 1349-1370 (2015)

T-cadherin is a glycosyl-phosphatidylinositol (GPI) anchored member of the cadherin superfamily involved in the guidance of migrating cells. We have previously shown that in vivo T-cadherin overexpression leads to increased melanoma primary tumor gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d9111f34f5110503ff0c56885ccccc
https://pubmed.ncbi.nlm.nih.gov/26197340

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Synthesis and evaluation of new antitumor 3-aminomethyl-4,11-dihydroxynaphtho[2,3-f]indole-5,10-diones

Autor: Jan Balzarini, Yves Pommier, Dmitry N. Kaluzhny, V. N. Buyanov, Yuri N. Luzikov, Keli Agama, Nina A. Lesnaya, Andrey E. Shchekotikhin, Vladimir I. Romanenko, Valeria A. Glazunova, Helena M. Treshalina, Alexander A. Shtil, Maria N. Preobrazhenskaya, Lyubov G. Dezhenkova

Publikováno v: European journal of medicinal chemistry. 86

A series of new 3-aminomethyl-4,11-dihydroxynaphtho[2,3- f ]indole-5,10-diones 6 – 13 bearing the cyclic diamine in the position 3 of the indole ring was synthesized. The majority of new compounds demonstrated a superior cytotoxicity than doxorubic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf04568e1cb02ad6be91e4cd1b89f3da
https://pubmed.ncbi.nlm.nih.gov/25244612

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Anticancer Enzyme L-Lysine α-Oxidase: Properties and Application Perspectives

Autor: Galina K. Guerassimova, Galina A. Firsova, Temir T. Berezov, Ludmila A. Sedakova, Helena M. Treshalina, Elena V. Lukasheva, Natalia V. Gogichaeva

Publikováno v: Applied Biochemistry and Biotechnology. 88:267-274

Fungal L-lysine α-oxidase (1.4.3.14) (LO) from Trichodermaharzianum Rifai presents an oxidoreductase with a firmly attached coenzyme—FAD. This stable enzyme catalyzes an oxidative deamination of L-lysine yielding hydrogen peroxide, ammonia, and α

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a82368fcbbaada7cc0e9111a91ed6391
https://doi.org/10.1385/abab:88:1-3:267

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