Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Helena M Kondow-McConaghy"'
Autor:
Aziz M. Mezlini, Eamon Caddigan, Allison Shapiro, Ernesto Ramirez, Helena M. Kondow-McConaghy, Justin Yang, Kerry DeMarco, Pejman Naraghi-Arani, Luca Foschini
Publikováno v:
Contemporary Clinical Trials Communications, Vol 33, Iss , Pp 101113- (2023)
Background: Studies for developing diagnostics and treatments for infectious diseases usually require observing the onset of infection during the study period. However, when the infection base rate incidence is low, the cohort size required to measur
Externí odkaz:
https://doaj.org/article/b80db760670644eea92451e76fe08d48
Autor:
Aziz M. Mezlini, Eamon Caddigan, Allison Shapiro, Ernesto Ramirez, Helena M. Kondow-McConaghy, Justin Yang, Kerry DeMarco, Pejman Naraghi-Arani, Luca Foschini
Studies for developing diagnostics and treatments for infectious diseases usually require observing the onset of infection during the study period. However, when the infection base rate incidence is low, the cohort size required to measure an effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::362fa0ca06784ef20d7ff3366fc707a2
https://doi.org/10.1101/2022.03.03.22271504
https://doi.org/10.1101/2022.03.03.22271504
Autor:
Helena M Kondow-McConaghy, Jean-Philippe Pellois, Alfredo Erazo-Oliveras, Rudolph L. Juliano, Kristina Najjar, Nandhini Muthukrishnan
Publikováno v:
ACS Chem Biol
Cell-penetrating peptides (CPPs) are routinely used for the delivery of macromolecules into live human cells. To enter the cytosolic space of cells, CPPs typically permeabilize the membrane of endosomes. In turn, several approaches have been develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf58ecf29d1c3314a290108464a48ca
https://doi.org/10.1021/acschembio.0c00319
https://doi.org/10.1021/acschembio.0c00319
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 50 (2018)
Cell-penetrating peptides (CPPs) are typically prone to endocytic uptake into human cells. However, they are often inefficient at escaping from endosomes, which limits their ability to deliver cargos into cells. This review highlights the efforts tha
Externí odkaz:
https://doaj.org/article/7da251bbe3c7473b8c2b1623850d5d48
Autor:
Andrea L. J. Marschall, Helena M Kondow-McConaghy, Jean-Philippe Pellois, Rudolph L. Juliano, Dakota J. Brock, Elizabeth Hager, Alfredo Erazo-Oliveras, Kristin Graham, Kristina Najjar, Stefan Dübel, Jason Allen
Publikováno v:
ACS Chem Biol
Ineffective cellular delivery is a common problem in numerous biological applications. Developing delivery reagents that work robustly in a variety of experimental settings remains a challenge. Herein, we report how peptides derived from the prototyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dc05f2cb41c69cf1a3858fd5f2f0fb
https://doi.org/10.1021/acschembio.9b00585
https://doi.org/10.1021/acschembio.9b00585
Autor:
Zlatko Brkljača, Mengqiu Jiang, Dakota J. Brock, Mario Vazdar, Jason Allen, Junjie Zhang, Hays S. Rye, Helena M Kondow-McConaghy, Jean-Philippe Pellois, Lauren Kustigian
Publikováno v:
Cell Chem Biol
Many cellular delivery reagents enter the cytosolic space of cells by escaping the lumen of endocytic organelles and, more specifically, late endosomes. The mechanisms involved in endosomal membrane permeation remain largely unresolved, which impedes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3dda6495e60ec9345d44af46bc500ae
https://pubmed.ncbi.nlm.nih.gov/32783962
https://pubmed.ncbi.nlm.nih.gov/32783962
Autor:
Helena M Kondow-McConaghy, Jason Allen, Jean-Philippe Pellois, Zlatko Brkljača, Mengqiu Jiang, Junjie Zhang, Lauren Kustigian, Mario Vazdar, Hays S. Rye, Dakota J. Brock
Publikováno v:
SSRN Electronic Journal.
Many cellular delivery reagents enter the cytosolic space of cells by escaping the lumen of endocytic organelles and, more specifically, late endosomes. The mechanisms involved in endosomal membrane permeation remain largely unresolved, which impedes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a36c33f3923b10480af5a1d09c841215
https://doi.org/10.2139/ssrn.3581354
https://doi.org/10.2139/ssrn.3581354
Publikováno v:
Bioconjugate chemistry. 30(2)
Cell delivery reagents often exploit the endocytic pathway as a route of cell entry. Once endocytosed, these reagents must overcome endosomal entrapment to ensure the release of their macromolecular cargo into the cytosol of cells. In this review, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc94b7ea839333f332ba1e2d176e29b8
https://pubmed.ncbi.nlm.nih.gov/30462487
https://pubmed.ncbi.nlm.nih.gov/30462487
Publikováno v:
Biomolecules, Vol 8, Iss 3, p 50 (2018)
Biomolecules
Biomolecules
Cell-penetrating peptides (CPPs) are typically prone to endocytic uptake into human cells. However, they are often inefficient at escaping from endosomes, which limits their ability to deliver cargos into cells. This review highlights the efforts tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5b88178a475a3f07c115edb61a8f2e
http://www.mdpi.com/2218-273X/8/3/50
http://www.mdpi.com/2218-273X/8/3/50