Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Helena Lindmark"'
Publikováno v:
Food & Nutrition Research, Vol 54, Iss 0, Pp 1-8 (2010)
The food chain contributes to a substantial part of greenhouse gas (GHG) emissions and growing evidence points to the urgent need to reduce GHGs emissions worldwide. Among suggestions were proposals to alter food consumption patterns by replacing ani
Externí odkaz:
https://doaj.org/article/262e950515e54d779f071e911d50bcbb
Autor:
Thomas Lundåsen, Eva-Marie Andersson, Michael Snaith, Helena Lindmark, Johanna Lundberg, Ann-Margret Östlund-Lindqvist, Bo Angelin, Mats Rudling
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37787 (2012)
Interruption of the enterohepatic circulation of bile acids increases cholesterol catabolism, thereby stimulating hepatic cholesterol synthesis from acetate. We hypothesized that such treatment should lower the hepatic acetate pool which may alter tr
Externí odkaz:
https://doaj.org/article/363f15d1450d4741babf3feaa4a1efe4
Autor:
Christian Tyrchan, Anna-Pia Palmgren, Hui-Fang Amy Chang, Yunhua Chen, Victoria Ullah, Karin Björhall, Annika Westin Eriksson, Rebecca Fransson, Mickael Mogemark, Tiiu Wennberg, Shuchun Zhao, Bold Peter, Linda Fredlund, Matthew Thomas, Eva Lamm Bergström, Nils Pemberton, Ulf Börjesson, Reed W. Smith, Mikael Brűlls, Johan Carlsson, Britt-Marie Fihn, Linda Öster, Mio Rodrigo Blomqvist, Hongbin Ge, Antonios Nikitidis, Wenzhen Yang, Anders Eriksson, Haijuan Huang, Sarah Lever, Perry Matthew, Kostas Karabelas, Helena Lindmark, Jens Petersen
Publikováno v:
Journal of medicinal chemistry. 64(12)
Starting from our previously described PI3Kγ inhibitors, we describe the exploration of structure-activity relationships that led to the discovery of highly potent dual PI3Kγδ inhibitors. We explored changes in two positions of the molecules, incl
Autor:
Sofia, Winslow, Lina, Odqvist, Sarah, Diver, Rebecca, Riise, Suado, Abdillahi, Cecilia, Wingren, Helena, Lindmark, Annika, Wellner, Sofia, Lundin, Linda, Yrlid, Elisabeth, Ax, Ratko, Djukanovic, Sriram, Sridhar, Andrew, Higham, Dave, Singh, Thomas, Southworth, Christopher E, Brightling, Henric K, Olsson, Zala, Jevnikar
Publikováno v:
The European respiratory journal. 58(4)
Interleukin (IL)-6 trans-signalling (IL-6TS) is emerging as a pathogenic mechanism in chronic respiratory diseases; however, the drivers of IL-6TS in the airways and the phenotypic characteristic of patients with increased IL-6TS pathway activation r
Autor:
S.I. Duchemin, H. Stålhammar, Marie Paulsson, M. Stenholdt Hansen, L. Buhelt Johansen, W.F. Fikse, Helena Lindmark-Månsson, Maria Glantz, Dirk-Jan de Koning, Kajsa Nilsson
Publikováno v:
Journal of dairy science. 103(8)
Milk that does not coagulate after rennet addition, also called noncoagulating (NC) milk, is unwanted in cheese production due to prolonged processing time. Amounts of whey and casein proteins, genetic variants, as well as posttranslational modificat
Autor:
Helena Lindmark-Månsson, W.F. Fikse, Dirk-Jan de Koning, M. Stenholdt Hansen, L. Buhelt Johansen, Maria Glantz, Marie Paulsson, Kajsa Nilsson, H. Stålhammar, S.I. Duchemin
Publikováno v:
Journal of dairy science. 103(9)
The rennet-induced coagulation ability of milk is important in cheese production. For Swedish Red Dairy Cattle (RDC), this ability is reduced because of a high prevalence of noncoagulating (NC) milk. In this study, we simultaneously combined genetic
Autor:
Helena Lindmark, Pia Hansson, Göran Dahl, Graham Cotton, Colin J. Dunsmore, Klaus Doering, Wayne P. Bowen, Ian L. Dale, Helen Boyd, Felix Nicolaus
Publikováno v:
ASSAY and Drug Development Technologies. 16:372-383
Fluorescence assay technologies are commonly used in high-throughput screening because of their sensitivity and ease of use. Different technologies have their characteristics and the rationale for choosing one over the other can differ between projec
Autor:
Liisa Byberg, Annika Smedman, Monika Johansson, Agnes Abrahamson, Henrik Hansson, Åse Lundh, Jonas A. Ohlsson, Helena Lindmark-Månsson
Publikováno v:
International Dairy Journal. 73:151-154
Lactose, glucose and galactose contents in milk and fermented milk products and their lactose-free alternatives, were determined. Storage of products up to the best-before dates had no effect on carbohydrate composition. Total galactose content in yo
Autor:
Maria Henriksson, Anna-Karin Modin Edman, Christian Swensson, Helena Lindmark-Månsson, Annika Smedman
Publikováno v:
Journal of the Science of Food and Agriculture. 97:4890-4897
Animal agriculture has been criticised in terms of its sustainability from several perspectives. Ruminants such as dairy cows can transform inedible, low-quality protein in roughage and by-products from the food industry into the high-quality protein
Autor:
Linda Öster, Helena Lindmark, Ina Terstiege, Jens Petersen, Perry Matthew, Tor Svensson, Christian Tyrchan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:679-687
A novel class of potent PI3Kδ inhibitors with >1000-fold selectivity against other class I PI3K isoforms is described. Optimization of the substituents on a triazole aminopyrazine scaffold, emerging from an in-house PI3Kα program, turned moderately