Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Helena L. Borges"'
Autor:
José Alexandre Salerno, Thayana Torquato, Jairo R. Temerozo, Livia Goto-Silva, Karina Karmirian, Mayara A. Mendes, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Letícia R Q. Souza, Isis M. Ornelas, Carla P. Veríssimo, Luiz Guilherme H S. Aragão, Gabriela Vitória, Carolina S G. Pedrosa, Suelen da Silva Gomes Dias, Vinicius Cardoso Soares, Teresa Puig-Pijuan, Vinícius Salazar, Rafael Dariolli, Diogo Biagi, Daniel R. Furtado, Luciana Barreto Chiarini, Helena L. Borges, Patrícia T. Bozza, Marilia Zaluar P. Guimarães, Thiago M.L. Souza, Stevens K. Rehen
Publikováno v:
PeerJ, Vol 9, p e12595 (2021)
SARS-CoV-2 infects cardiac cells and causes heart dysfunction. Conditions such as myocarditis and arrhythmia have been reported in COVID-19 patients. The Sigma-1 receptor (S1R) is a ubiquitously expressed chaperone that plays a central role in cardio
Externí odkaz:
https://doaj.org/article/654771cd45c94c0ebd7a55057203f3db
Autor:
Luiz Guilherme H. S. Aragão, Júlia T. Oliveira, Jairo R. Temerozo, Mayara A. Mendes, José Alexandre Salerno, Carolina S. G. Pedrosa, Teresa Puig-Pijuan, Carla P. Veríssimo, Isis M. Ornelas, Thayana Torquato, Gabriela Vitória, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Suelen da Silva Gomes Dias, Vinicius Cardoso Soares, Letícia R. Q. Souza, Karina Karmirian, Livia Goto-Silva, Diogo Biagi, Estela M. Cruvinel, Rafael Dariolli, Daniel R. Furtado, Patrícia T. Bozza, Helena L. Borges, Thiago M. L. Souza, Marília Zaluar P. Guimarães, Stevens K. Rehen
Publikováno v:
PeerJ, Vol 9, p e12262 (2021)
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can infect several organs, especially impacting respiratory capacity. Among the extrapulmonary manifestations of COVID-19 is myocardi
Externí odkaz:
https://doaj.org/article/ce3f2fb7034a4198b040ce2921144372
Autor:
Carolina da S.G. Pedrosa, Livia Goto-Silva, Jairo R. Temerozo, Leticia R.Q. Souza, Gabriela Vitória, Isis M. Ornelas, Karina Karmirian, Mayara A. Mendes, Ismael C. Gomes, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Vinicius Cardoso Soares, Suelen da Silva Gomes Dias, José A. Salerno, Teresa Puig-Pijuan, Julia T. Oliveira, Luiz G.H.S. Aragão, Thayana C.Q. Torquato, Carla Veríssimo, Diogo Biagi, Estela M. Cruvinel, Rafael Dariolli, Daniel R. Furtado, Helena L. Borges, Patrícia T. Bozza, Stevens Rehen, Thiago Moreno L. Souza, Marília Zaluar P. Guimarães
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102436- (2021)
Coronavirus disease 2019 (COVID-19) was initially described as a viral infection of the respiratory tract. It is now known, however, that several other organs are affected, including the brain. Neurological manifestations such as stroke, encephalitis
Externí odkaz:
https://doaj.org/article/ab1ba8301e984f0faf1cf30367661855
Autor:
Rossana C. Soletti, Deborah Biasoli, Nathassya A.L.V. Rodrigues, João M.A. Delou, Renata Maciel, Vera L.A. Chagas, Rodrigo A.P. Martins, Stevens K. Rehen, Helena L. Borges
Publikováno v:
Translational Oncology, Vol 10, Iss 5, Pp 726-733 (2017)
Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Current chemotherapy regimens include a combination of 5-fluorouracil (5-FU) and cisplatin, but more efficient therapy strategies are needed to increase 5-year surviv
Externí odkaz:
https://doaj.org/article/6a89825565aa4be68ea71bc7f2e28105
Publikováno v:
Cells, Vol 8, Iss 9, p 1013 (2019)
Combination chemotherapy has been a mainstay in cancer treatment for the last 60 years. Although the mechanisms of action and signaling pathways affected by most treatments with single antineoplastic agents might be relatively well understood, most c
Externí odkaz:
https://doaj.org/article/6cfa520b675d41ff99a05cf469709d35
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 88, Iss 4, Pp 2257-2275
ABSTRACT Physiological processes, as autophagy, proliferation and apoptosis are affected during carcinogenesis. Restoring cellular sensitivity to apoptotic stimuli, such as the antineoplastic cocktails, has been explored as a strategy to eliminate ca
Externí odkaz:
https://doaj.org/article/ff824e5254e74cf28764a5d80a417cc3
Autor:
Jean Y.J. Wang, Helena L. Borges, Lars Eckmann, Michael E. Ramirez, Priya Sridevi, Anil Sadarangani, Rossana C. Soletti, Jinbo Han
PDF file - 2529K, S1 Similar levels of TUNEL-positive cells were observed in the splenic tissue sections from Rb+/+ and RbMI/MI mice at 24 hr after PBS (Veh) or TNF-α i.p. injection. Scale bar: 50 μm. **p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4a527d0bf603d8601b2be7dc7f67b1
https://doi.org/10.1158/1541-7786.22509795
https://doi.org/10.1158/1541-7786.22509795
Autor:
Jean Y.J. Wang, Helena L. Borges, Lars Eckmann, Michael E. Ramirez, Priya Sridevi, Anil Sadarangani, Rossana C. Soletti, Jinbo Han
Tumor necrosis factor (TNF)-α promotes tumor development under chronic inflammation. Because TNF also activates caspase-8, selective inhibition of TNF-induced extrinsic apoptosis would be required for inflammation-associated tumor growth. In a mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8603c131ef1fa8068dbcc5396ea06415
https://doi.org/10.1158/1541-7786.c.6539400
https://doi.org/10.1158/1541-7786.c.6539400
Autor:
Livia Goto-Silva, Carolina Q. Sacramento, Marília Zaluar P. Guimarães, Rafael Dariolli, Isis M. Ornelas, Thiago Moreno L. Souza, Estela Cruvinel, Luiz Guilherme H. S. Aragão, Jairo R. Temerozo, Helena L. Borges, Teresa Puig-Pijuan, Júlia T. Oliveira, Diogo Biagi, José Alexandre Salerno, Daniel Rodrigues Furtado, Thayana Torquato, Stevens K. Rehen, Karina Karmirian, Natalia Fintelman-Rodrigues, Patrícia T. Bozza, Mayara Abud Mendes, Vinicius Cardoso Soares, Leticia R. Q. Souza, Carolina da S. G. Pedrosa, Carla Veríssimo, Gabriela Vitória, Suelen da Silva Gomes Dias
Publikováno v:
PeerJ
PeerJ, Vol 9, p e12262 (2021)
PeerJ, Vol 9, p e12262 (2021)
Coronavirus disease 2019 (COVID-19) is caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can infect several organs and lead to loss of vital organ function, especially impacting respiratory capacity. Among the extrapulmonary mani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60f15579adba1dddbc2a6c4574dab9d
http://europepmc.org/articles/PMC8504461
http://europepmc.org/articles/PMC8504461
Autor:
Diêgo Madureira de Oliveira, Stevens K. Rehen, Jorge Clarêncio, Helena L. Borges, Giselle Pinto de Faria Lopes, Eudes da Silva Velozo, Ezequiel Pereira, Tereza C C Silva, Bruno P.S. Pitanga, N.J. Menezes-Filho, Rafael dos Santos Costa, Silvia Lima Costa, Vivaldo Moura-Neto, Songeli Menezes Freire
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 18:1386-1393
Background: A glioblastoma is a primary CNS tumor that is more aggressive and lethal than other brain tumors. Its location, rapid proliferation, invasive growth, angiogenesis and immunosuppression are the main factors that limit its treatment, making
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4631bbc24fc6b2aa032ff2e7fa8a5e68
https://doi.org/10.2174/1871520618666180412122101
https://doi.org/10.2174/1871520618666180412122101