Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Helena Lönnies"'
Autor:
Robin Hinsch, Yuji Teramura, Kristina Nilsson-Ekdahl, Nina Heldring, Osama A. Hamad, Bo Nilsson, Lech Ignatowicz, Guido Moll, Matthew Locke, Helena Lönnies, Jessica J. Alm, Katarina Le Blanc, Lena von Bahr, Lindsay C. Davies, John D. Lambris, Lillemor Stenbeck-Funke
Publikováno v:
Stem Cells. 32:2430-2442
We have recently reported that therapeutic mesenchymal stromal cells (MSCs) have low engraftment and trigger the instant blood mediated inflammatory reaction (IBMIR) after systemic delivery to patients, resulting in compromised cell function. In orde
Autor:
Peetra U. Magnusson, Anne-Marie Connolly-Andersen, Osama A. Hamad, Olle Ringdén, Graciela Elgue, Katarina Le Blanc, Kristina Nilsson-Ekdahl, Yuji Teramura, Bo Nilsson, Guido Moll, Javier Sanchez, Lena von Bahr, Ida Rasmusson-Duprez, Lillemor Funke, Olle Korsgren, Helena Lönnies
Publikováno v:
Stem Cells. 30:1565-1574
Multipotent mesenchymal stromal cells (MSCs) are tested in numerous clinical trials. Questions have been raised concerning fate and function of these therapeutic cells after systemic infusion. We therefore asked whether culture-expanded human MSCs el
Autor:
Rolf Kiessling, A. John Barrett, Silvia Nava, C. Christian Johansson, Mikael Sundin, Helena Lönnies, Padraig D'Arcy, Berit Sundberg, Katarina Le Blanc, Dimitrios Mougiakakos
Publikováno v:
Journal of Immunotherapy. 34:336-342
Multipotent mesenchymal stromal cells (MSCs) have immunosuppressive capacity but the exact mechanism by which they suppress proliferation of T lymphocytes is not fully understood. Recently, the characteristics and function of regulatory T lymphocytes
Autor:
A. John Barrett, Mehmet Uzunel, Åsa-Lena Dackland, Olle Ringdén, Katarina Le Blanc, Helena Lönnies, Birger Christensson, Mikael Sundin
Publikováno v:
Journal of Immunotherapy. 32:755-764
Multipotent mesenchymal stromal cells (MSC) are increasingly used to treat refractory graft-versus-host-disease and other complications following hematopoietic stem cell transplantation (HSCT). We evaluated immunogenicity of HLA-mismatched MSC infuse
Publikováno v:
Cytotherapy. 11:129-136
Mesenchymal stromal cells (MSC) can be expanded in vitro for clinical use and have been evaluated in clinical trials as immunosuppressants and to heal damaged tissues. We investigated the impact of freezing and prolonged storage on cell viability, pr
Publikováno v:
Cytotherapy. 10:238-242
Multipotent mesenchymal stromal cells (MSC) are candidates for cellular therapy in regenerative medicine and as treatment of graft-versus-host-disease (GvHD) after hematopoietic stem cell (HSC) transplantation. It has been suggested that MSC may be t
Autor:
Helena Lönnies, Axana Haggar, Anna Norrby-Teglund, Muzaffar Hussain, Mathias Herrmann, Jan-Ingmar Flock
Publikováno v:
Infection and Immunity. 71:2310-2317
In this study we have shown that Eap (extracellular adherence protein) plays a role in the internalization process of Staphylococcus aureus into eukaryotic cells. Eap is a protein that is mostly extracellularly and to a lesser extent is bound to the
Publikováno v:
European Journal of Oral Sciences. 109:182-186
The aim of this study was two-fold: firstly, to study the effect of high fluoride concentrations on carbohydrate metabolism in Streptococcus mutans present in biofilms on hydroxyapatite; and, secondly, to evaluate the effect of fluoride-bound hydroxy
Publikováno v:
Current Microbiology. 28:91-96
An arginine carboxypeptidase was isolated from the cell walls ofStreptococcus mitis ATCC 15909 by mutanolysin extraction of the walls. The enzyme was purified 32-fold by gel filtration on Sephacryl S-300, affinity chromatography on Arginine-Sepharose
Autor:
Katarina Le Blanc, Philip Stephens, Lindsay C. Davies, Matthew Locke, Helena Lönnies, Berit Sundberg, Kerstin Rosendahl, Cecilia Götherström
Publikováno v:
Stem cells and development. 21(9)
Oral mucosal lamina propria progenitor cells (OMLP-PCs) are a novel, clonally derived PC population of neural crest origin with the potential to differentiate down both mesenchymal and neuronal cell lineages. In this study we aimed to determine the i