Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Helena Jernberg-Wiklund"'
Autor:
Patrick Nylund, Alba Atienza Párraga, Jakob Haglöf, Elke De Bruyne, Eline Menu, Berta Garrido-Zabala, Anqi Ma, Jian Jin, Fredrik Öberg, Karin Vanderkerken, Antonia Kalushkova, Helena Jernberg-Wiklund
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-16 (2021)
Abstract Multiple myeloma (MM) is a heterogeneous haematological disease that remains clinically challenging. Increased activity of the epigenetic silencer EZH2 is a common feature in patients with poor prognosis. Previous findings have demonstrated
Externí odkaz:
https://doaj.org/article/102657295ae543ceae01381242f3b978
Autor:
Antonia Kalushkova, Patrick Nylund, Alba Atienza Párraga, Andreas Lennartsson, Helena Jernberg-Wiklund
Publikováno v:
Epigenomes, Vol 5, Iss 4, p 22 (2021)
Aberrant DNA methylation, dysregulation of chromatin-modifying enzymes, and microRNAs (miRNAs) play a crucial role in haematological malignancies. These epimutations, with an impact on chromatin accessibility and transcriptional output, are often ass
Externí odkaz:
https://doaj.org/article/4876a47cec874f74bedda65c14faac8d
Publikováno v:
Epigenomes, Vol 2, Iss 3, p 16 (2018)
The enhancer of zeste homolog 2 (EZH2) is the enzymatic subunit of the polycomb repressive complex 2 (PRC2) that exerts important functions during normal development as well as disease. PRC2 through EZH2 tri-methylates histone H3 lysine tail residue
Externí odkaz:
https://doaj.org/article/5613180eb1884b2cb0168f2f2876079a
Autor:
Jamileh Hashemi, Claire Worrall, Daiana Vasilcanu, Mårten Fryknäs, Luqman Sulaiman, Mohsen Karimi, Wen-Hui Weng, Weng-Onn Lui, Christina Rudduck, Magnus Axelson, Helena Jernberg-Wiklund, Leonard Girnita, Olle Larsson, Catharina Larsson
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14757 (2011)
BACKGROUND: Picropodophyllin (PPP) is a promising novel anti-neoplastic agent that efficiently kills tumor cells in vitro and causes tumor regression and increased survival in vivo. We have previously reported that PPP treatment induced moderate tole
Externí odkaz:
https://doaj.org/article/ec708690f09a4924ab882776863652fb
Autor:
Antonia Kalushkova, Mårten Fryknäs, Miguel Lemaire, Charlotte Fristedt, Prasoon Agarwal, Maria Eriksson, Sarah Deleu, Peter Atadja, Anders Osterborg, Kenneth Nilsson, Karin Vanderkerken, Fredrik Oberg, Helena Jernberg-Wiklund
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11483 (2010)
Multiple myeloma (MM) is a genetically heterogeneous disease, which to date remains fatal. Finding a common mechanism for initiation and progression of MM continues to be challenging. By means of integrative genomics, we identified an underexpressed
Externí odkaz:
https://doaj.org/article/1f3893bcdaf24c6d97ea336a9a5f5ad7
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Extensive genome-wide sequencing efforts have unveiled the intricate regulatory potential of long non-protein coding RNAs (lncRNAs) within the domain of haematological malignancies. Notably, lncRNAs have been found to directly modulate chromatin arch
Externí odkaz:
https://doaj.org/article/472fedd422e543d3a4451b395ebb962f
Autor:
Patrick Nylund, Berta Garrido-Zabala, Alba Atienza Párraga, Louella Vasquez, Paul Theodor Pyl, George Mickhael Harinck, Anqi Ma, Jian Jin, Fredrik Öberg, Antonia Kalushkova, Helena Jernberg Wiklund
Publikováno v:
Haematologica, Vol 109, Iss 2 (2023)
Multiple myeloma is a heterogeneous hematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells. Despite novel therapies, multiple myeloma remains clinically challenging. A com
Externí odkaz:
https://doaj.org/article/54d146f1cd6c4084ae909eaf599b99d0
Autor:
Karin Vanderkerken, Helena Jernberg-Wiklund, Ben Van Camp, Magnus Axelson, Olle Larsson, Peter Atadja, Anders Österborg, Elke De Bruyne, Els Van Valckenborgh, Eline Menu, Prasoon Agarwal, Charlotte Fristedt, Miguel Lemaire
PDF file - 60K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c5193c820a4500010d0f840762b611
https://doi.org/10.1158/1078-0432.22443767
https://doi.org/10.1158/1078-0432.22443767
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Resource Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f9e62c1e38cb49885bbd558c5c889e
https://doi.org/10.1158/0008-5472.22433306
https://doi.org/10.1158/0008-5472.22433306
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Supplementary figure 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1912492597cfade9206b22e304f40fbd
https://doi.org/10.1158/0008-5472.22433336
https://doi.org/10.1158/0008-5472.22433336