Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Helena Havelková"'
Autor:
Imtissal Krayem, Yahya Sohrabi, Helena Havelková, Elena S. Gusareva, Hynek Strnad, Marie Čepičková, Valeryia Volkova, Iryna Kurey, Jarmila Vojtíšková, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Leishmaniasis, a disease caused by parasites of Leishmania spp., endangers more than 1 billion people living in endemic countries and has three clinical forms: cutaneous, mucocutaneous, and visceral. Understanding of individual differences in suscept
Externí odkaz:
https://doaj.org/article/3e718d78d1e24996b2ce7247054e2c1b
Autor:
Imtissal Krayem, Yahya Sohrabi, Eliška Javorková, Valeriya Volkova, Hynek Strnad, Helena Havelková, Jarmila Vojtíšková, Aigerim Aidarova, Vladimír Holáň, Peter Demant, Marie Lipoldová
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Differences in frequencies of blood cell subpopulations were reported to influence the course of infections, atopic and autoimmune diseases, and cancer. We have discovered a unique mouse strain B10.O20 containing extremely high frequency of myeloid-d
Externí odkaz:
https://doaj.org/article/8e0953753a104350a2d56780f5471812
Autor:
Tatyana Kobets, Marie Čepičková, Valeriya Volkova, Yahya Sohrabi, Helena Havelková, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Leishmaniasis is a serious health problem in many countries, and continues expanding to new geographic areas including Europe and USA. This disease, caused by parasites of Leishmania spp. and transmitted by phlebotomine sand flies, causes up to 1.3 m
Externí odkaz:
https://doaj.org/article/fdd06331037e4948bdbcd5e1670b89d6
Autor:
Yahya Sohrabi, Valeryia Volkova, Tatyana Kobets, Helena Havelková, Imtissal Krayem, Martina Slapničková, Peter Demant, Marie Lipoldová
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Interferon-induced GTPases [guanylate-binding proteins (GBPs)] play an important role in inflammasome activation and mediate innate resistance to many intracellular pathogens, but little is known about their role in leishmaniasis. We therefore studie
Externí odkaz:
https://doaj.org/article/c748843ad5b24914b8a43c50bb511c1c
Autor:
Yahya Sohrabi, Helena Havelková, Tetyana Kobets, Matyáš Šíma, Valeriya Volkova, Igor Grekov, Taťána Jarošíková, Iryna Kurey, Jarmila Vojtíšková, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2282 (2013)
BACKGROUND: L. tropica can cause both cutaneous and visceral leishmaniasis in humans. Although the L. tropica-induced cutaneous disease has been long known, its potential to visceralize in humans was recognized only recently. As nothing is known abou
Externí odkaz:
https://doaj.org/article/afe245a0a2154623b2d311010dda6c2c
Autor:
Tetyana Kobets, Helena Havelková, Igor Grekov, Valeriya Volkova, Jarmila Vojtíšková, Martina Slapničková, Iryna Kurey, Yahya Sohrabi, Milena Svobodová, Peter Demant, Marie Lipoldová
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1667 (2012)
BACKGROUND: Leishmaniasis is a disease caused by protozoan parasites of genus Leishmania. The frequent involvement of Leishmania tropica in human leishmaniasis has been recognized only recently. Similarly as L. major, L. tropica causes cutaneous leis
Externí odkaz:
https://doaj.org/article/1b843d864a224403a831bc6a115c8981
Autor:
Matyáš Síma, Helena Havelková, Lei Quan, Milena Svobodová, Taťána Jarošíková, Jarmila Vojtíšková, Alphons P M Stassen, Peter Demant, Marie Lipoldová
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1173 (2011)
BackgroundTrypanosoma brucei brucei infects livestock, with severe effects in horses and dogs. Mouse strains differ greatly in susceptibility to this parasite. However, no genes controlling these differences were mapped.MethodsWe studied the genetic
Externí odkaz:
https://doaj.org/article/5c390e675c114dcd956262f108f03994
Autor:
Petra Mikšátková, Katerina Nepomucka, Lenka Sarnova, Gizem Oyman-Eyrilmez, Radislav Sedlacek, Gerhard Wiche, Martin Kuchar, Karel Chalupsky, Alzbeta Kalendova, Ondrej Fabian, Marketa Jirouskova, Helena Havelková, Oldrich Benada, Bjoern Schuster, Martin Gregor
Publikováno v:
Journal of Hepatology. 68:1006-1017
Background & Aims Plectin, a highly versatile cytolinker protein, controls intermediate filament cytoarchitecture and cellular stress response. In the present study, we investigate the role of plectin in the liver under basal conditions and in experi
Autor:
Valeriya Volkova, Marie Čepičková, Marie Lipoldová, Milena Svobodová, Peter Demant, Yahya Sohrabi, Helena Havelková, Tatyana Kobets
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Leishmaniasis is a serious health problem in many countries, and continues expanding to new geographic areas including Europe and USA. This disease, caused by parasites of Leishmania spp. and transmitted by phlebotomine sand flies, causes up to 1.3 m
Autor:
Milena Svobodová, Marie Lipoldová, Helena Havelková, Jana Badalová, Igor Grekov, Tetyana Kobets
Publikováno v:
Nature Protocols. 5:1074-1080
This protocol describes an improved and optimized PCR-ELISA method for detection and quantification of Leishmania parasites in host tissues. Unlike other DNA-based assays, this method uses digoxigenin- and biotin-labeled primers. This eliminates the