Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Helena Hagner Gram"'
Autor:
George Pappas, Sebastian Howen Nesgaard Munk, Kenji Watanabe, Quentin Thomas, Zita Gál, Helena Hagner Gram, MyungHee Lee, Daniel Gómez-Cabello, Dimitris Christos Kanellis, Pedro Olivares-Chauvet, Dorthe Helena Larsen, Lea Haarup Gregersen, Apolinar Maya-Mendoza, Panagiotis Galanos, Jiri Bartek
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111979- (2023)
Summary: The role of MDC1 in the DNA damage response has been extensively studied; however, its impact on other cellular processes is not well understood. Here, we describe the role of MDC1 in transcription as a regulator of RNA polymerase II (RNAPII
Externí odkaz:
https://doaj.org/article/50019a16f1e04bee8a3f5e43aa9acc20
Autor:
Scott Maynard, Arnaldur Hall, Panagiotis Galanos, Salvatore Rizza, Tatsuro Yamamoto, Helena Hagner Gram, Sebastian H N Munk, Muhammad Shoaib, Claus Storgaard Sørensen, Vilhelm A Bohr, Mads Lerdrup, Apolinar Maya-Mendoza, Jiri Bartek
Publikováno v:
Maynard, S, Hall, A, Galanos, P, Rizza, S, Yamamoto, T, Gram, H H, Munk, S H N, Shoaib, M, Sørensen, C S, Bohr, V A, Lerdrup, M, Maya-Mendoza, A & Bartek, J 2022, ' Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD + pathway ', Nucleic Acids Research, vol. 50, no. 17, pp. 9948-9965 . https://doi.org/10.1093/nar/gkac741
Mutations in the lamin A/C gene (LMNA) cause laminopathies such as the premature aging Hutchinson Gilford progeria syndrome (HGPS) and altered lamin A/C levels are found in diverse malignancies. The underlying lamin-associated mechanisms remain poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9707d12a18f7c0a887b36b7ff7e0281
https://doi.org/10.1093/nar/gkac741
https://doi.org/10.1093/nar/gkac741