Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Helena Gbelcová"'
Autor:
Helena Gbelcová, Silvie Rimpelová, Adriana Jariabková, Patrik Macášek, Petra Priščáková, Tomáš Ruml, Jana Šáchová, Jan Kubovčiak, Michal Kolář, Libor Vítek
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Statins, the drugs used for the treatment of hypercholesterolemia, have come into the spotlight not only as chemoadjuvants, but also as potential stem cell modulators in the context of regenerative therapy. In our study, we compared the in v
Externí odkaz:
https://doaj.org/article/a2b1444916ff47fd88579fb1c2a86160
Autor:
Simona Dobiasová, Nikoletta Szemerédi, Denisa Kučerová, Kamila Koucká, Radka Václavíková, Helena Gbelcová, Tomáš Ruml, Enrique Domínguez-Álvarez, Gabriella Spengler, Jitka Viktorová
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Long-term treatment of cancer with chemotherapeutics leads to the development of resistant forms that reduce treatment options. The main associated mechanism is the overexpression of transport proteins, particularly P-glycoprotein (P-gp, ABC
Externí odkaz:
https://doaj.org/article/ea8477d4bc2143b1b6b2e40b1317c4e3
Publikováno v:
Polymers, Vol 15, Iss 21, p 4228 (2023)
Injectable bioadhesive hydrogels, known for their capacity to carry substances and adaptability in processing, offer great potential across various biomedical applications. They are especially promising in minimally invasive stem cell-based therapies
Externí odkaz:
https://doaj.org/article/561ed2092b724b8f91e947035e9ce0ba
Autor:
Petra Priščáková, Miroslav Korbeľ, Zuzana Nižňanská, Katarína Letkovská, Katarína Sušienková, Vanda Repiská, Daniel Böhmer, Helena Gbelcová
Publikováno v:
BioTechniques, Vol 69, Iss 6, Pp 427-435 (2020)
Syncytin-1 (gene ERVW-1) has been proposed as a marker of pre-eclampsia and malfunctions in placental development. Placenta is heterogeneous tissue, hence the method of biopsy can significantly affect the outcome of analyses. A total of 44 placentae
Externí odkaz:
https://doaj.org/article/89899f64609b4e579cfc51dda58c6f44
Autor:
Helena Gbelcová, Silvie Rimpelová, Zdeněk Knejzlík, Jana Šáchová, Michal Kolář, Hynek Strnad, Vanda Repiská, Walter Cosimo D’Acunto, Tomáš Ruml, Libor Vítek
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Statin treatment of hypercholesterolemia is accompanied also with depletion of the mevalonate intermediates, including farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP) necessary for proper function of small GTP
Externí odkaz:
https://doaj.org/article/1564237be422436784cf65eb07216dd9
Autor:
Ján Víglaš, Simona Dobiasová, Jitka Viktorová, Tomáš Ruml, Vanda Repiská, Petra Olejníková, Helena Gbelcová
Publikováno v:
Molecules, Vol 26, Iss 19, p 6025 (2021)
Fighting resistance to antibiotics and chemotherapeutics has brought bioactive peptides to the fore. Peptaibols are short α-aminoisobutyric acid-containing peptides produced by Trichoderma species. Here, we studied the production of peptaibols by Tr
Externí odkaz:
https://doaj.org/article/84a642d8bd4c4976b6f30f9c5034c7d7
Publikováno v:
Molecules, Vol 26, Iss 14, p 4254 (2021)
Plasma medicine is a new field focusing on biomedical and clinical applications of cold gas plasmas, including their anticancer effects. Cold plasmas can be applied directly or indirectly as plasma-activated liquids (PAL). The effects of plasma-activ
Externí odkaz:
https://doaj.org/article/e617caf1cba14f0b9b27171b7299b520
Publikováno v:
Molecules, Vol 26, Iss 12, p 3528 (2021)
Statins have been widely used for the treatment of hypercholesterolemia due to their ability to inhibit HMG-CoA reductase, the rate-limiting enzyme of de novo cholesterol synthesis, via the so-called mevalonate pathway. However, their inhibitory acti
Externí odkaz:
https://doaj.org/article/c244182daf034fcaba7cfcb59a3d4577
Autor:
Lucia Krasničanová, Rami Saade, Petra Priščáková, Helena Gbelcová, Katarína Kaľavská, Marián Karaba, Juraj Benca, Michal Mego, Vanda Repiská
Publikováno v:
Klinicka onkologie. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978b686f080250f6de68753198d17bb7
https://doi.org/10.48095/ccko2023130
https://doi.org/10.48095/ccko2023130
Autor:
Simona Dobiasová, Nikoletta Szemerédi, Denisa Kučerová, Kamila Koucká, Radka Václavíková, Helena Gbelcová, Tomáš Ruml, Enrique Domínguez-Álvarez, Gabriella Spengler, Jitka Viktorová
Publikováno v:
Scientific reports. 12(1)
Long-term treatment of cancer with chemotherapeutics leads to the development of resistant forms that reduce treatment options. The main associated mechanism is the overexpression of transport proteins, particularly P-glycoprotein (P-gp, ABCB1). In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd82d0fab80295c5b80f9647ee44a886
https://pubmed.ncbi.nlm.nih.gov/35449387
https://pubmed.ncbi.nlm.nih.gov/35449387