Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Helena F Florindo"'
Autor:
Rita C. Acúrcio, Ron Kleiner, Daniella Vaskovich‐Koubi, Bárbara Carreira, Yulia Liubomirski, Carolina Palma, Adva Yeheskel, Eilam Yeini, Ana S. Viana, Vera Ferreira, Carlos Araújo, Michael Mor, Natalia T. Freund, Eran Bacharach, João Gonçalves, Mira Toister‐Achituv, Manon Fabregue, Solene Matthieu, Capucine Guerry, Ana Zarubica, Sarit Aviel‐Ronen, Helena F. Florindo, Ronit Satchi‐Fainaro
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract The first approved vaccines for human use against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are nanotechnology‐based. Although they are modular, rapidly produced, and can reduce disease severity, the currently availa
Externí odkaz:
https://doaj.org/article/b5734eacdf3b49c7be9c99d042cb5913
Autor:
Saumya Kumar, Afonso P. Basto, Filipa Ribeiro, Silvia C. P. Almeida, Patricia Campos, Carina Peres, Nadia Pulvirenti, Sarwah Al-Khalidi, Anna Kilbey, Jimena Tosello, Eliane Piaggio, Momtchilo Russo, Margarida Gama-Carvalho, Seth B. Coffelt, Ed W. Roberts, Jens Geginat, Helena F. Florindo, Luis Graca
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-21 (2024)
Abstract Effective antibody responses are essential to generate protective humoral immunity. Different inflammatory signals polarize T cells towards appropriate effector phenotypes during an infection or immunization. Th1 and Th2 cells have been asso
Externí odkaz:
https://doaj.org/article/b1ab6f0616b246af8630d5bef2fc7871
Autor:
João eConniot, Joana M Silva, Joana G Fernandes, Liana C. Silva, Rogério eGaspar, Steve eBrocchini, Helena F Florindo, Teresa Silva Barata
Publikováno v:
Frontiers in Chemistry, Vol 2 (2014)
Cancer is one of the most common diseases afflicting people globally. New therapeutic approaches are needed due to the complexity of cancer as a disease. Many current treatments are very toxic and have modest efficacy at best. Increased understanding
Externí odkaz:
https://doaj.org/article/39af9ac464434b2ca1f6df75f6f501b8
Autor:
Ana I. Matos, Carina Peres, Barbara Carreira, Liane I. F. Moura, Rita C. Acúrcio, Theresa Vogel, Erik Wegener, Filipa Ribeiro, Marta B. Afonso, Fábio M. F. Santos, Águeda Martínez‐Barriocanal, Diego Arango, Ana S. Viana, Pedro M. P. Góis, Liana C. Silva, Cecília M. P. Rodrigues, Luis Graca, Rainer Jordan, Ronit Satchi‐Fainaro, Helena F. Florindo
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Immune checkpoint blockade reaches remarkable clinical responses. However, even in the most favorable cases, half of these patients do not benefit from these therapies in the long term. It is hypothesized that the activation of host immunity
Externí odkaz:
https://doaj.org/article/4b20ef243e294bf990270de291c0adb7
Publikováno v:
Frontiers in Medical Technology, Vol 5 (2023)
Externí odkaz:
https://doaj.org/article/348e0c8c1b3b4f0aa082d60292026e71
Autor:
Sabina Pozzi, Anna Scomparin, Dikla Ben-Shushan, Eilam Yeini, Paula Ofek, Alessio D. Nahmad, Shelly Soffer, Ariel Ionescu, Antonella Ruggiero, Adi Barzel, Henry Brem, Thomas M. Hyde, Iris Barshack, Sanju Sinha, Eytan Ruppin, Tomer Weiss, Asaf Madi, Eran Perlson, Inna Slutsky, Helena F. Florindo, Ronit Satchi-Fainaro
Publikováno v:
JCI Insight, Vol 7, Iss 17 (2022)
Development of resistance to chemo- and immunotherapies often occurs following treatment of melanoma brain metastasis (MBM). The brain microenvironment (BME), particularly astrocytes, cooperate toward MBM progression by upregulating secreted factors,
Externí odkaz:
https://doaj.org/article/7d80f87848d14503bacd860b5076b699
Autor:
Luís Costa, Luis Graca, Rita C. Acúrcio, Sabina Pozzi, Barbara Carreira, Marta Pojo, Nuria Gómez-Cebrián, Sandra Casimiro, Adelaide Fernandes, Andreia Barateiro, Vitor Farricha, Joaquim Brito, Ana Paula Leandro, Jorge A R Salvador, Leonor Puchades-Carrasco, Ronit Satchi-Fainaro, Rita C. Guedes, Helena F. Florindo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Inhibiting programmed cell death protein 1 (PD-1) or PD-ligand 1 (PD-L1) has shown exciting clinical outcomes in diverse human cancers. So far, only monoclonal antibodies are approved as PD-1/PD-L1 inhibitors. While significant clinical ou
Externí odkaz:
https://doaj.org/article/48b3a2c79c7342a9bccafeec9e0b33da
Autor:
David Pires, Manoj Mandal, Ana I. Matos, Carina Peres, Maria João Catalão, José Miguel Azevedo-Pereira, Ronit Satchi-Fainaro, Helena F. Florindo, Elsa Anes
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 729 (2023)
The golden age of antibiotics for tuberculosis (TB) is marked by its success in the 1950s of the last century. However, TB is not under control, and the rise in antibiotic resistance worldwide is a major threat to global health care. Understanding th
Externí odkaz:
https://doaj.org/article/fd4ab8f8cb614e7bbe58b5d7533af708
Autor:
Carlos Rodolfo, Dalinda Eusébio, Cathy Ventura, Renato Nunes, Helena F. Florindo, Diana Costa, Ângela Sousa
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1369 (2021)
In current times, DNA vaccines are seen as a promising approach to treat and prevent diseases, such as virus infections and cancer. Aiming at the production of a functional and effective plasmid DNA (pDNA) delivery system, four chitosan polymers, dif
Externí odkaz:
https://doaj.org/article/b8e1180badfd4849a54015dc369980b3
Autor:
Barbara Carreira, Rita A. Acúrcio, Sabina Pozzi, Ron Kleiner, Liane I. Moura, Ana I. Matos, Daniela vaskovich, Carina Peres, Adelaide Fernandes, Sara Xapelli, Ronit Satchi-Fainaro, Helena F. Florindo
Publikováno v:
Cancer Research. 83:835-835
Sixty percent of melanoma patients present brain metastases, having low response rates to current systemic therapies, which do not prolong survival. New therapeutic options to address this clinical need are urgent. Here, we report the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edff0e471b62de015878db1b3c507d4e
https://doi.org/10.1158/1538-7445.am2023-835
https://doi.org/10.1158/1538-7445.am2023-835