Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Helena Erlandsson"'
Autor:
Raya Saleh, Erik Sundberg, Mia Olsson, Katarina Tengvall, Lars Alfredsson, Ingrid Kockum, Leonid Padyukov, Helena Erlandsson Harris
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune disease and the most common chronic rheumatological disease affecting children under the age of 16. The etiology of JIA remains poorly understood, but evidence suggests a
Externí odkaz:
https://doaj.org/article/d8bc63d7b96a48848186f553c014605d
Autor:
Naili, Josefine E., Ahmed, Aisha S., Hedström, Margareta, Simonsen, Morten Bilde, Broström, Eva W., Harris, Helena Erlandsson, Végvári, Ákos, Aulin, Cecilia
Publikováno v:
In Osteoarthritis and Cartilage Open March 2025 7(1)
Akademický článek
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Autor:
Heshuang Qu, Erik Sundberg, Cecilia Aulin, Manoj Neog, Karin Palmblad, Anna Carin Horne, Fredrik Granath, Alexandra Ek, Erik Melén, Mia Olsson, Helena Erlandsson Harris
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background This study aimed to perform an immunoprofiling of systemic juvenile idiopathic arthritis (sJIA) in order to define biomarkers of clinical use as well as reveal new immune mechanisms. Methods Immunoprofiling of plasma samples from
Externí odkaz:
https://doaj.org/article/869822238e8b4c7da7c4103d2be7da08
Autor:
Huan Yang, Peter Lundbäck, Lars Ottosson, Helena Erlandsson-Harris, Emilie Venereau, Marco E. Bianchi, Yousef Al-Abed, Ulf Andersson, Kevin J. Tracey
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-7 (2021)
Abstract Background High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is passively released during cell death and secreted by activated cells of many lineages. HMGB1 contains three conserved
Externí odkaz:
https://doaj.org/article/15eb4334e8e64c59a1d86b216d8e0b0f
Autor:
Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Ulf Andersson
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Abstract Background Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. HMGB1 is a nuclear protein released extracellularly during proinflammatory lytic cell death or secreted by activated macrophages, N
Externí odkaz:
https://doaj.org/article/a55408e06b2342e3acfc4027a7532cf9
Autor:
Malin Hildenborg, Jessica Kåhlin, Fredrik Granath, Anna Schening, Anna Granström, Anette Ebberyd, Lena Klevenvall, Henrik Zetterberg, Jinming Han, Todd T. Schlegel, Robert Harris, Helena Erlandsson Harris, Lars I. Eriksson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Surgery triggers a systemic inflammatory response that ultimately impacts the brain and associates with long-term cognitive impairment. Adequate regulation of this immune surge is pivotal for a successful surgical recovery. We explored the temporal i
Externí odkaz:
https://doaj.org/article/0d687330368942378f2c3183a93f08ae
Autor:
Heshuang Qu, Rebecka Heinbäck, Henna Salo, Ewoud Ewing, Alexander Espinosa, Cecilia Aulin, Helena Erlandsson Harris
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 779 (2022)
Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. In different conditions, macrophage polarization can be induced by high-mobility group box 1 (HMGB1), a nuclear D
Externí odkaz:
https://doaj.org/article/0ddf1793533b4285a2d8375fd3ed7f89
Autor:
Agnieszka Sowinska, Merlin Rensing, Lena Klevenvall, Manoj Neog, Peter Lundbäck, Helena Erlandsson Harris
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Extracellular HMGB1 acts as an alarmin in multiple autoimmune diseases. While its release and functions have been extensively studied, there is a substantial lack of knowledge regarding HMGB1 regulation at the site of inflammation. Herein we show tha
Externí odkaz:
https://doaj.org/article/a52cd3fa8d1f495ba8e8cab328503574
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-10 (2018)
Abstract Background High mobility group box 1 (HMGB1) protein is a central endogenous inflammatory mediator contributing to the pathogenesis of several inflammatory disorders. HMGB1 interacts with toll-like receptors (TLRs) but contradictory evidence
Externí odkaz:
https://doaj.org/article/4d5d448d097743ff955ba1f10c699265