Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Helena Deriš"'
Autor:
Panayiotis Louca, Tamara Štambuk, Azra Frkatović-Hodžić, Ana Nogal, Massimo Mangino, Sarah E. Berry, Helena Deriš, George Hadjigeorgiou, Jonathan Wolf, Martina Vinicki, Paul W. Franks, Ana M. Valdes, Tim D. Spector, Gordan Lauc, Cristina Menni
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background A dysregulated postprandial metabolic response is a risk factor for chronic diseases, including type 2 diabetes mellitus (T2DM). The plasma protein N-glycome is implicated in both lipid metabolism and T2DM risk. Hence, we first in
Externí odkaz:
https://doaj.org/article/14876c1e22a74b02acad0eb3e4d62e9c
Autor:
Alessia Visconti, Niccolò Rossi, Helena Deriš, Karla A Lee, Maja Hanić, Irena Trbojević-Akmačić, Andrew M. Thomas, Laura A. Bolte, Johannes R. Björk, Jahlisa S. Hooiveld-Noeken, Ruth Board, Mark Harland, Julia Newton-Bishop, Mark Harries, Joseph J. Sacco, Paul Lorigan, Heather M. Shaw, Elisabeth G.E. de Vries, Rudolf S.N. Fehrmann, Rinse K. Weersma, Tim D. Spector, Paul Nathan, Geke A. P. Hospers, Peter Sasieni, Veronique Bataille, Gordan Lauc, Mario Falchi
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of melanoma and other cancers. However, no reliable biomarker of survival or response has entered the clinic to identify those patients with melanoma who are mo
Externí odkaz:
https://doaj.org/article/50b511b7f9af46e6993f096da9d33865
Autor:
Aoife Murray, Gillian Gough, Ana Cindrić, Frano Vučković, David Koschut, Vincenzo Borelli, Dražen J. Petrović, Ana Bekavac, Ante Plećaš, Valentina Hribljan, Reinhard Brunmeir, Julija Jurić, Maja Pučić-Baković, Anita Slana, Helena Deriš, Azra Frkatović, Jűrgen Groet, Niamh L. O’Brien, Hong Yu Chen, Yee Jie Yeap, Frederic Delom, Steven Havlicek, Luke Gammon, Sarah Hamburg, Carla Startin, Hana D’Souza, Dinko Mitrečić, Mijana Kero, Ljubica Odak, Božo Krušlin, Željka Krsnik, Ivica Kostović, Jia Nee Foo, Yuin-Han Loh, Norris Ray Dunn, Susana de la Luna, Tim Spector, Ingeborg Barišić, Michael S.C. Thomas, Andre Strydom, Claudio Franceschi, Gordan Lauc, Jasminka Krištić, Ivan Alić, Dean Nižetić
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104692- (2023)
Summary: Background: People with Down syndrome (DS) show clinical signs of accelerated ageing. Causative mechanisms remain unknown and hypotheses range from the (essentially untreatable) amplified-chromosomal-instability explanation, to potential act
Externí odkaz:
https://doaj.org/article/fccbd6f8ccf04865a74224623e30be79
Autor:
Helena Deriš, Petra Tominac, Frano Vučković, Nina Briški, Arne Astrup, Ellen E. Blaak, Gordan Lauc, Ivan Gudelj
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Obesity-induced inflammation activates the adaptive immune system by altering immunoglobulin G (IgG) glycosylation in a way to produce more proinflammatory antibodies. The IgG glycome has already been well studied, and its alterations are correlated
Externí odkaz:
https://doaj.org/article/9d6db160fde9411699f5c5162f7879ab
Autor:
Maja Hanić, Frano Vučković, Helena Deriš, Claire Bewshea, Simeng Lin, James R. Goodhand, Tariq Ahmad, Irena Trbojević-Akmačić, Nicholas A. Kennedy, Gordan Lauc, PANTS Consortium
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 954 (2023)
Crohn’s disease (CD) is a chronic inflammation of the digestive tract that significantly impairs patients’ quality of life and well-being. Anti-TNF biologicals revolutionised the treatment of CD, yet many patients do not adequately respond to suc
Externí odkaz:
https://doaj.org/article/b18d46dadc5a4d579794ac102865802b
Autor:
Nina Šimunić-Briški, Robert Zekić, Vedran Dukarić, Mateja Očić, Azra Frkatović-Hodžić, Helena Deriš, Gordan Lauc, Damir Knjaz
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 762 (2023)
Regular exercise improves health, modulating the immune system and impacting inflammatory status. Immunoglobulin G (IgG) N-glycosylation reflects changes in inflammatory status; thus, we investigated the impact of regular exercise on overall inflamma
Externí odkaz:
https://doaj.org/article/efebfdc5a3d04e2bb06201039f4e1d3c
Autor:
Helena Deriš, Domagoj Kifer, Ana Cindrić, Tea Petrović, Ana Cvetko, Irena Trbojević-Akmačić, Ivana Kolčić, Ozren Polašek, Louise Newson, Tim Spector, Cristina Menni, Gordan Lauc
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103897- (2022)
Summary: Gonadal hormones affect immunoglobulin G (IgG) glycosylation, and the more proinflammatory IgG glycome composition might be one of the molecular mechanisms behind the increased proinflammatory phenotype in perimenopause. Using ultra-high-per
Externí odkaz:
https://doaj.org/article/85e9d0d3a95a4655b1cac2cde739efca
Autor:
Consortium, Maja Hanić, Frano Vučković, Helena Deriš, Claire Bewshea, Simeng Lin, James R. Goodhand, Tariq Ahmad, Irena Trbojević-Akmačić, Nicholas A. Kennedy, Gordan Lauc, PANTS Consortium PANTS
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 954
Crohn’s disease (CD) is a chronic inflammation of the digestive tract that significantly impairs patients’ quality of life and well-being. Anti-TNF biologicals revolutionised the treatment of CD, yet many patients do not adequately respond to suc
Autor:
Irena Trbojević-Akmačić, Guinevere S. M. Lageveen-Kammeijer, Bram Heijs, Tea Petrović, Helena Deriš, Manfred Wuhrer, Gordan Lauc
Publikováno v:
Chemical Reviews, 122(20), 15865-15913. AMER CHEMICAL SOC
Glycomics aims to identify the structure and function of the glycome, the complete set of oligosaccharides (glycans), produced in a given cell or organism, as well as to identify genes and other factors that gover n glycosylation. This challenging en
Autor:
Helena Deriš, Petra Tominac, Frano Vučković, Arne Astrup, Ellen E. Blaak, Gordan Lauc, Ivan Gudelj
Publikováno v:
International journal of molecular sciences, 23(24):15772. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15772
Deriš, H, Tominac, P, Vučković, F, Astrup, A, Blaak, E E, Lauc, G & Gudelj, I 2022, ' Susceptibility of human plasma N-glycome to low-calorie and different weight-maintenance diets ', International Journal of Molecular Sciences, vol. 23, no. 24, 15772 . https://doi.org/10.3390/ijms232415772
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15772
Deriš, H, Tominac, P, Vučković, F, Astrup, A, Blaak, E E, Lauc, G & Gudelj, I 2022, ' Susceptibility of human plasma N-glycome to low-calorie and different weight-maintenance diets ', International Journal of Molecular Sciences, vol. 23, no. 24, 15772 . https://doi.org/10.3390/ijms232415772
Aberrant plasma protein glycosylation is associated with a wide range of diseases, including diabetes, cardiovascular, and immunological disorders. To investigate plasma protein glycosylation alterations due to weight loss and successive weight-maint