Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Helena Cimarosti"'
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-15 (2018)
Abstract Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people every year and so far, there are no therapeutic cures
Externí odkaz:
https://doaj.org/article/384dc66ceab64a53b2a77f59d8e83591
Autor:
Letícia Martins Cândido, Jaquelini Betta Canever, Ana Lúcia Danielewicz, Bruno de Souza Moreira, M Fernanda Lima-Costa, Núbia Carelli, Helena Cimarosti
Publikováno v:
European Geriatric Medicine. 14:307-315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d66bd5c46c944f9971f6ff653588a1
https://doi.org/10.1007/s41999-023-00751-8
https://doi.org/10.1007/s41999-023-00751-8
Publikováno v:
Ericks Sousa Soares
Considering that neonatal pain is a relevant matter given its implications and consequences, many neonates, particularly those undergoing critical care, are subjected to analgo-sedation therapies, which commonly includes treatment with opioids and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58c84581fc8c184743cb112c7051e0d
https://doi.org/10.1055/s-0042-1758873
https://doi.org/10.1055/s-0042-1758873
Publikováno v:
Purinergic Signalling
Zanella, C A, Henley, J M, Wilkinson, K A, Cimarosti, H I & Tasca, C I 2020, ' Guanosine modulates SUMO2/3-ylation in neurons and astrocytes via adenosine receptors. ', Purinergic Signalling, vol. (2020) . https://doi.org/10.1007/s11302-020-09723-0
Zanella, C A, Henley, J M, Wilkinson, K A, Cimarosti, H I & Tasca, C I 2020, ' Guanosine modulates SUMO2/3-ylation in neurons and astrocytes via adenosine receptors. ', Purinergic Signalling, vol. (2020) . https://doi.org/10.1007/s11302-020-09723-0
SUMOylation is a post-translational modification (PTM) whereby members of the Small Ubiquitin-like MOdifier (SUMO) family of proteins are conjugated to lysine residues in target proteins. SUMOylation has been implicated in a wide range of physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cb2a3e74f45ad5c18e771247dd280e
http://europepmc.org/articles/PMC7524998
http://europepmc.org/articles/PMC7524998
Publikováno v:
Junqueira, S C, Centeno, E G Z, Wilkinson, K & Cimarosti, H I 2019, ' Post-translational modifications of Parkinson's disease-related proteins : Phosphorylation, SUMOylation and Ubiquitination ', Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, vol. 1865, no. 8, pp. 2001-2007 . https://doi.org/10.1016/j.bbadis.2018.10.025
Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of dopaminergic neurons in the nigrostriatal pathway. The etiology of PD remains unclear and most cases are sporadic, however genetic mutations in more than 20 proteins ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c53981bbd9bf77bcd34cd6a49f9e47
https://doi.org/10.1016/j.bbadis.2018.10.025
https://doi.org/10.1016/j.bbadis.2018.10.025
Autor:
Ericks Sousa Soares, Felipe Vanz, Vagner Fagnani Linartevichi, Helena Cimarosti, Thereza Christina Monteiro de Lima
Publikováno v:
Behavioural brain research. 419
Memory is the ability to store, retrieve and use information that requires a progressive time-dependent stabilization process known as consolidation to be established. The hippocampus is essential for processing all the information that forms memory,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b8145488c0c87b5ac6d9eca4368e29
https://pubmed.ncbi.nlm.nih.gov/34871704
https://pubmed.ncbi.nlm.nih.gov/34871704
Autor:
Vasco C, Silveirinha, Hong, Lin, Shota, Tanifuji, Sumiko, Mochida, Graeme S, Cottrell, Helena, Cimarosti, Gary J, Stephens
Publikováno v:
Cell calcium. 93
SUMOylation is an important post-translational modification process involving covalent attachment of SUMO (Small Ubiquitin-like MOdifier) protein to target proteins. Here, we investigated the potential for SUMO-1 protein to modulate the function of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f729ee9376a0a903885bd3bb945136f
https://pubmed.ncbi.nlm.nih.gov/33360835
https://pubmed.ncbi.nlm.nih.gov/33360835
Autor:
Shota Tanifuji, Graeme S. Cottrell, Sumiko Mochida, Hong Lin, Gary J. Stephens, Helena Cimarosti, Vasco Silveirinha
Publikováno v:
Cell Calcium. 93:102326
SUMOylation is an important post-translational modification process involving covalent attachment of SUMO (Small Ubiquitin-like MOdifier) protein to target proteins. Here, we investigated the potential for SUMO-1 protein to modulate the function of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f8eb710bcb066e85839f0968db82cfb
https://doi.org/10.1016/j.ceca.2020.102326
https://doi.org/10.1016/j.ceca.2020.102326
Publikováno v:
Journal of Neurochemistry. 137:673-686
Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by cardinal motor signs such as rigidity, bradykinesia or rest tremor that arise from a significant death of dopaminergic neurons. Non-dopaminergic degenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55193eac2d18cb29789dc6b270b5ede1
https://doi.org/10.1111/jnc.13599
https://doi.org/10.1111/jnc.13599
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-15 (2018)
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-15 (2018)
Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people every year and so far, there are no therapeutic cures available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f3e999e9eb95c154d90cb4b923550d3d
https://pubmed.ncbi.nlm.nih.gov/29788997
https://pubmed.ncbi.nlm.nih.gov/29788997