Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Helena C F, Oliveira"'
Autor:
Thiago Rentz, Gabriel G. Dorighello, Renata R. dos Santos, Lohanna M. Barreto, Israelle N. Freitas, Carolina M. Lazaro, Daniela S. Razolli, Patricia M. Cazita, Helena C. F. Oliveira
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1556 (2023)
CETP activity reduces plasma HDL-cholesterol concentrations, a correlate of an increased risk of atherosclerotic events. However, our recent findings suggest that CETP expression in macrophages promotes an intracellular antioxidant state, reduces fre
Externí odkaz:
https://doaj.org/article/e92237ebb2d747e2802a20ff49b59a65
Autor:
Estela Lorza-Gil, Marta García-Arevalo, Bianca Cristine Favero, Maria Cristina C. Gomes-Marcondes, Helena C. F. Oliveira
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background HMG-CoA reductase inhibitors (statins) are cholesterol-lowering drugs widely used to treat hypercholesterolemia and prevent cardiovascular disease. Statins are generally well tolerated, but adverse reactions may occur, particularl
Externí odkaz:
https://doaj.org/article/5497777dfaa54cb7b2fb2e904ddeadb5
Autor:
Gabriel G. Dorighello, Leandro H. P. Assis, Thiago Rentz, Joseane Morari, Monique F. M. Santana, Marisa Passarelli, Neale D. Ridgway, Anibal E. Vercesi, Helena C. F. Oliveira
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1734 (2022)
Plasma cholesteryl ester transfer protein (CETP) activity diminishes HDL-cholesterol levels and thus may increase atherosclerosis risk. Experimental evidence suggests CETP may also exhibit anti-inflammatory properties, but local tissue-specific funct
Externí odkaz:
https://doaj.org/article/a479ef00329548a4961a129e0c26d3d6
Autor:
Thiago Rentz, Amarylis C. B. A. Wanschel, Leonardo de Carvalho Moi, Estela Lorza-Gil, Jane C. de Souza, Renata R. dos Santos, Helena C. F. Oliveira
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
An early event in atherogenesis is the recruitment and infiltration of circulating monocytes and macrophage activation in the subendothelial space. Atherosclerosis subsequently progresses as a unresolved inflammatory disease, particularly in hypercho
Externí odkaz:
https://doaj.org/article/d2946ae866844d6abd0f5a91b3eff3dd
Autor:
Amarylis C. B. A. Wanschel, Daniele M. Guizoni, Estela Lorza-Gil, Alessandro G. Salerno, Adriene A. Paiva, Gabriel G. Dorighello, Ana Paula Davel, Wayne Balkan, Joshua M. Hare, Helena C. F. Oliveira
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 69 (2021)
Endothelial dysfunction precedes atherosclerosis and is an independent predictor of cardiovascular events. Cholesterol levels and oxidative stress are key contributors to endothelial damage, whereas high levels of plasma high-density lipoproteins (HD
Externí odkaz:
https://doaj.org/article/6e5b59f4fb194832873252fbe9e0250e
Autor:
Ana C. Marques, Estela N. B. Busanello, Diogo N. de Oliveira, Rodrigo R. Catharino, Helena C. F. Oliveira, Anibal E. Vercesi
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Statins are the preferred therapy to treat hypercholesterolemia. Their main action consists of inhibiting the cholesterol biosynthesis pathway. Previous studies report mitochondrial oxidative stress and membrane permeability transition (MPT) of sever
Externí odkaz:
https://doaj.org/article/f6f8e8a054614aaebdd2e7edc2d54a4d
Autor:
Claudia D C, Navarro, Annelise, Francisco, Tiago R, Figueira, Juliana A, Ronchi, Helena C F, Oliveira, Anibal E, Vercesi, Roger F, Castilho
Publikováno v:
European journal of pharmacology. 917
The mechanisms by which a high-fat diet (HFD) promotes non-alcoholic fatty liver disease (NAFLD) appear to involve liver mitochondrial dysfunction and redox imbalance. The functional loss of the enzyme NAD(P)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58878b5d40cf7fb3cc8a72336ebd8c08
https://pubmed.ncbi.nlm.nih.gov/35032488
https://pubmed.ncbi.nlm.nih.gov/35032488
Publikováno v:
Antioxidantsredox signaling. 36(13-15)
Significance: Altered plasma triglyceride metabolism and changes in dietary fatty acid types and levels are major contributors to the development of metabolic and cardiovascular diseases such as fa...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e8f8e7eb1e2fda66c5f8dacf9f75ee
https://pubmed.ncbi.nlm.nih.gov/34409856
https://pubmed.ncbi.nlm.nih.gov/34409856
Autor:
Ruither O. G. Carolino, Helena Fonseca Raposo, Thaís Marques da Silva, Helena C. F. Oliveira, Gleuber Henrique Marques-Oliveira, Valéria Ernestânia Chaves, Isis do Carmo Kettelhut, Maria Antonieta Rissato Garófalo, Helder Magno Silva Valadares, Janete Aparecida Anselmo-Franci
Publikováno v:
Lipids. 54:231-244
Our previous studies show that cafeteria diet increases body adiposity, plasma insulin levels, and sympathetic activity to brown adipose tissue (BAT) and white adipose tissue (WAT) of Wistar rats, leading to rapid and progressive changes in the metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a3351667e61c24f8bdcb4326672248
https://doi.org/10.1002/lipd.12144
https://doi.org/10.1002/lipd.12144
Autor:
Gabriel G. Dorighello, Juliana C. Rovani, Helena C. F. Oliveira, Thiago Rentz, Leandro H.P. Assis, Anibal E. Vercesi, Bruno A. Paim
Publikováno v:
Journal of atherosclerosis and thrombosis. 29(6)
Aim Atherosclerosis is responsible for high morbidity and mortality rates around the world. Local arterial oxidative stress is involved in all phases of atherosclerosis development. Mitochondria is a relevant source of the oxidants, particularly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325e9ac07fea3b59ed8be26b46a407ae
https://pubmed.ncbi.nlm.nih.gov/34565766
https://pubmed.ncbi.nlm.nih.gov/34565766