Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Helena Borland"'
Autor:
Helena Borland Madsen, Jon Ambæk Durhuus, Ove Andersen, Per thor Straten, Anne Rahbech, Claus Desler
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in widespread morbidity and mortality, with a significant portion of the affected population experiencing long-term health complications. This review explores the mechanisms of mitoch
Externí odkaz:
https://doaj.org/article/4083a3d8cd894abaa18d46f573504756
Autor:
Helena Borland Madsen, Claudia Navarro, Emilie Gasparini, Jae-Hyeon Park, Zhiquan Li, Deborah L. Croteau, Vilhelm A. Bohr
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionDuring aging, many cellular processes, such as autophagic clearance, DNA repair, mitochondrial health, metabolism, nicotinamide adenine dinucleotide (NAD+) levels, and immunological responses, become compromised. Urolithin A (UA) and Nico
Externí odkaz:
https://doaj.org/article/3e103a9947594f0087e35ad8f9ab37bb
Autor:
Susanne K. Hansen, Tina C. Stummann, Helena Borland, Lis F. Hasholt, Zeynep Tümer, Jørgen E. Nielsen, Mikkel A. Rasmussen, Troels T. Nielsen, Justus C.A. Daechsel, Karina Fog, Poul Hyttel
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 306-317 (2016)
The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3) is caused by a CAG-repeat expansion in the ATXN3 gene. In this study, induced pluripotent stem cell (iPSC) lines were established from two SCA3 patients. Dermal fibroblasts were repro
Externí odkaz:
https://doaj.org/article/689832b5ce1347ec94da084f4ef67ec1
Autor:
Susanne K. Hansen, Helena Borland, Lis F. Hasholt, Zeynep Tümer, Jørgen E. Nielsen, Mikkel A. Rasmussen, Troels T. Nielsen, Tina C. Stummann, Karina Fog, Poul Hyttel
Publikováno v:
Stem Cell Research, Vol 16, Iss 3, Pp 589-592 (2016)
Spinocerebellar ataxia type 3 (SCA3) is a dominantly inherited neurodegenerative disease caused by an expansion of the CAG-repeat in ATXN3. In this study, induced pluripotent stem cells (iPSCs) were generated from SCA3 patient dermal fibroblasts by e
Externí odkaz:
https://doaj.org/article/c00a25cb37a8441caa255b51978e7333
Akademický článek
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Akademický článek
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Autor:
Madsen, Helena Borland, Park, J-H, Hou, Y, Li, Z, Rasmussen, Lene J., Croteau, D. L., Bohr, Vilhelm A., Akbari, Mansour, Chu, X.
Publikováno v:
Madsen, Park, Hou, Li, Rasmussen, Croteau, Bohr, Akbari. The cGAS-STING signaling pathway is modulated by urolithin A. Mechanisms of Ageing and Development. 2024;217
Externí odkaz:
https://hdl.handle.net/10037/35182
Akademický článek
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Autor:
Schmauck-Medina, Tomás Alejandro, Molière, Adrian, Lautrup, Sofie Hindkjær, Zhang, Jianying, Chlopicki, Stefan, Madsen, Helena Borland, Cao, Shuqin, Soendenbroe, Casper, Mansell, Els, Vestergaard, Mark Bitsch, Li, Zhiquan, Shiloh, Yosef, Opresko, Patricia L., Egly, Jean-Marc, Kirkwood, Thomas, Verdin, Eric, Bohr, Vilhelm A., Cox, Lynne S., Stevnsner, Tinna, Rasmussen, Lene Juel, Fang, Fei
Publikováno v:
Schmauck-Medina, Tomás Alejandro Molière, Adrian Lautrup, Sofie Hindkjær Zhang, Jianying Chlopicki, Stefan Madsen, Helena Borland Cao, Shuqin Soendenbroe, Casper Mansell, Els Vestergaard, Mark Bitsch Li, Zhiquan Shiloh, Yosef Opresko, Patricia L. Egly, Jean-Marc Kirkwood, Thomas Verdin, Eric Bohr, Vilhelm A. Cox, Lynne S. Stevnsner, Tinna Rasmussen, Lene Juel Fang, Fei . New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary. Aging. 2022, 14(16), 6829-6839
Aging
Aging
Externí odkaz:
http://hdl.handle.net/10852/100170
Autor:
Tomas Schmauck-Medina, Adrian Molière, Sofie Lautrup, Jianying Zhang, Stefan Chlopicki, Helena Borland Madsen, Shuqin Cao, Casper Soendenbroe, Els Mansell, Mark Bitsch Vestergaard, Zhiquan Li, Yosef Shiloh, Patricia L. Opresko, Jean-Marc Egly, Thomas Kirkwood, Eric Verdin, Vilhelm A. Bohr, Lynne S. Cox, Tinna Stevnsner, Lene Juel Rasmussen, Evandro F. Fang
Publikováno v:
Schmauck-Medina, T, Molière, A, Lautrup, S, Zhang, J, Chlopicki, S, Madsen, H B, Cao, S, Soendenbroe, C, Mansell, E, Vestergaard, M B, Li, Z, Shiloh, Y, Opresko, P L, Egly, J M, Kirkwood, T, Verdin, E, Bohr, V A, Cox, L S, Stevnsner, T, Rasmussen, L J & Fang, E F 2022, ' New hallmarks of ageing : a 2022 Copenhagen ageing meeting summary ', Aging, vol. 14, no. 16, pp. 6829-6839 . https://doi.org/10.18632/aging.204248
Genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, loss of proteostasis, deregulated nutrient-sensing, cellular senescence, stem cell exhaustion, and altered intercellular communication were the original nine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0561f3f991fdf490afcba5864a09972c
https://curis.ku.dk/ws/files/319877704/aging_v14i16_204248.pdf
https://curis.ku.dk/ws/files/319877704/aging_v14i16_204248.pdf