Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Helena Bonciani Nader"'
Autor:
Vinicius Tadeu Ramos da Silva Grillo, Matheus Bertanha, Lenize da Silva Rodrigues, Marcelo Andrade de Lima, Pedro Luciano Mellucci Filho, Rafael Rahal Guaragna Machado, Edson Luiz Durigon, Nathália Dias Sertorio, Marjorie de Assis Golim, Andrei Moroz, Aline Márcia Marques Braz, Leonardo Nazário de Moraes, Marco Antonio Leite, Helena Bonciani Nader, Gustavo Constantino de Campos, Cristiane Rodrigues Guzzo Carvalho, Fábio Florença Cardoso, Angelo José Magro, Helga Caputo Nunes, Rejane Maria Tommasini Grotto, Rita de Cássia Alvarado, Maria Inês de Moura Campos Pardini, Marcone Lima Sobreira, Erika Alessandra Pellison Nunes da Costa, Alexandre Naime Barbosa, Carlos Magno Castelo Branco Fortaleza
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract To evaluate the safety and the potential antiviral treatment of inhaled enriched heparin in patients with COVID-19. The specific objectives were to investigate the anticoagulation profile, antiviral and anti-inflammatory effects, and respira
Externí odkaz:
https://doaj.org/article/52e49bab85b94a4c8730dedefeec15e7
Autor:
Danielle de Paula Moreira, Angela May Suzuki, André Luiz Teles e Silva, Elisa Varella-Branco, Maria Cecília Zorél Meneghetti, Gerson Shigeru Kobayashi, Mariana Fogo, Merari de Fátima Ramires Ferrari, Rafaela Regina Cardoso, Naila Cristina Vilaça Lourenço, Karina Griesi-Oliveira, Elaine Cristina Zachi, Débora Romeo Bertola, Karina de Souza Weinmann, Marcelo Andrade de Lima, Helena Bonciani Nader, Andrea Laurato Sertié, Maria Rita Passos-Bueno
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
Biallelic pathogenic variants in TBCK cause encephaloneuropathy, infantile hypotonia with psychomotor retardation, and characteristic facies 3 (IHPRF3). The molecular mechanisms underlying its neuronal phenotype are largely unexplored. In this study,
Externí odkaz:
https://doaj.org/article/b6157e43dbaf43568d0bef65c5a89565
Autor:
Carina Mucciolo Melo, Huawei Wang, Ken Fujimura, Jan Strnadel, Maria Cecília Zorél Meneghetti, Helena Bonciani Nader, Richard L. Klemke, Maria Aparecida Silva Pinhal
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Angiogenesis is the formation of new vessels from pre-existing vasculature. The heparan sulfate chains from endothelial cell proteoglycans interact with the major angiogenic factors, regulating blood vessels´ formation. Since the FDA´s first approv
Externí odkaz:
https://doaj.org/article/6919d55cbf844803a474e69767b05b14
Autor:
Thérèse Rachell Theodoro, Leandro Luongo Matos, Renan Pelluzzi Cavalheiro, Giselle Zenker Justo, Helena Bonciani Nader, Maria Aparecida Silva Pinhal
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Heparanase (HPSE) is an endo-beta-glucuronidase that degrades heparan sulfate (HS) chains on proteoglycans. The oligosaccharides generated by HPSE promote angiogenesis, tumor growth and metastasis. Heparanase-2 (HPSE2), a close ho
Externí odkaz:
https://doaj.org/article/214510b927d14efeaa7722520cb9c61c
Autor:
Marcelo Silva Watanabe, Thérèse Rachel Theodoro, Natália Lima Coelho, Aline Mendes, Monica Luzia Pereira Leonel, Ana Maria Mader, Helena Bonciani Nader, Sidney Glina, Maria Aparecida Silva Pinhal
Publikováno v:
Journal of Advanced Research, Vol 8, Iss 4, Pp 455-461 (2017)
Peyronie’s disease is characterized by fibrous plaque formation of the tunica albuginea, causing penile deformity and fertility problems. The aim of the present study was to investigate alterations in the extracellular matrix in Peyronie’s diseas
Externí odkaz:
https://doaj.org/article/666a2dc6b4dc401ea70d53acc46ce5de
Autor:
Sandra Obikawa Kyosen, Leny Toma, Helena Bonciani Nader, Marion Coting Braga, Vanessa Gonçalves Pereira, Sueli Canossa, João Bosco Pesquero, Vânia D’Almeida, Ana Maria Martins
Publikováno v:
Revista Paulista de Pediatria, Iss 0 (2019)
ABSTRACT Objective: To report the stabilization of urinary glycosaminoglicans (GAG) excretion and clinical improvements in patients with mucopolysaccharidosis type I (MPS I) under an alternative dose regimen of laronidase of 1.2 mg/kg every other wee
Externí odkaz:
https://doaj.org/article/38637534098d49dc82dca4878f97d736
Autor:
Priscilla Carneiro Hirai Nascimento, Elsa Yoko Kobayashi, Luiz Guilherme de Saboya Lenzi, João Baptista Gomes dos Santos, Helena Bonciani Nader, Flávio Faloppa
Publikováno v:
Acta Ortopédica Brasileira, Vol 24, Iss 2, Pp 98-101 (2016)
Objective : To evaluate and compare the behavior of glycosaminoglycans (GAGs) in Dupuytren disease (DD). Methods : This is an experimental study with 23 patients diagnosed with DD. Tissue collected through fasciectomy with incision type Brunner or Mc
Externí odkaz:
https://doaj.org/article/d9d3eea92c3c41d9befeb7ebcd91fe5d
Autor:
Carolina Meloni Vicente, Daiana Aparecida da Silva, Priscila Veronica Sartorio, Tiago Donizetti Silva, Sarhan Sydney Saad, Helena Bonciani Nader, Nora Manoukian Forones, Leny Toma
Publikováno v:
Analytical Cellular Pathology, Vol 2018 (2018)
Colorectal cancer is the third most common cancer worldwide, accounting for more than 610,000 mortalities every year. Prognosis of patients is highly dependent on the disease stage at diagnosis. Therefore, it is crucial to investigate molecules invol
Externí odkaz:
https://doaj.org/article/af96bd0c3b1e4999be6420cb2181d9f3
Autor:
Delio Eulalio Martins, Valquiria Pereira de Medeiros, Marcelo Wajchenberg, Edgar Julian Paredes-Gamero, Marcelo Lima, Rejane Daniele Reginato, Helena Bonciani Nader, Eduardo Barros Puertas, Flavio Faloppa
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203932 (2018)
OBJECTIVE:This study evaluates molecular, nutritional and biochemical alterations in human intervertebral discs between middle and old age. METHODS:Twenty-eight human lumbar intervertebral discs from donors were evaluated and separated into two group
Externí odkaz:
https://doaj.org/article/0b5663810e874d169b7dc905b81f840f
Autor:
Helena Bonciani Nader, Hugo Alexandre Oliveira Rocha, Edda Lisboa Leite, Luciana Guimarães Alves Filgueira, Juliana Luporini Dreyfuss, Dayanne Lopes Gomes, Sara Lima Cordeiro, Ivan Rui Lopes Albuquerque
Publikováno v:
Marine Drugs, Vol 11, Iss 8, Pp 2722-2740 (2013)
Fucan is a term that defines a family of homo- and hetero-polysaccharides containing sulfated l-fucose in its structure. In this work, a heterofucan (F2.0v) from the seaweed, Dictyota menstrualis, was evaluated as an antinociceptive and anti-inflamma
Externí odkaz:
https://doaj.org/article/48f064901dde47709eec1752db7c9072