Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Helena A. Jones"'
Autor:
Maria Lindahl, Jitka Petrlova, Jonathan Dalla-Riva, Sebastian Wasserstrom, Catarina Rippe, Joan Domingo-Espin, Dorota Kotowska, Ewa Krupinska, Christine Berggreen, Helena A. Jones, Karl Swärd, Jens O. Lagerstedt, Olga Göransson, Karin G. Stenkula
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 12, Pp 2248-2259 (2015)
ApoA-I, the main protein component of HDL, is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available. Remarkably, high-fat-fe
Externí odkaz:
https://doaj.org/article/0aa81832a4b14fbda3c35032f37a5812
Publikováno v:
Archives of disease in childhood - Education & practice edition. 107:392-396
Food insecurity is a major problem in the UK. It has been both highlighted and exacerbated by the COVID-19 pandemic, and particularly affects children and young people (CYP). The effects of inadequate nutrition manifest themselves in all stages of ch
Autor:
Tina Rönn, Petr Volkov, Cajsa Davegårdh, Tasnim Dayeh, Elin Hall, Anders H Olsson, Emma Nilsson, Asa Tornberg, Marloes Dekker Nitert, Karl-Fredrik Eriksson, Helena A Jones, Leif Groop, Charlotte Ling
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003572 (2013)
Epigenetic mechanisms are implicated in gene regulation and the development of different diseases. The epigenome differs between cell types and has until now only been characterized for a few human tissues. Environmental factors potentially alter the
Externí odkaz:
https://doaj.org/article/1f19764cecb8416a9d3bfcadb61b3b39
Autor:
Sebastian Wasserstrom, Mattias Ekstedt, Julia Blomdahl, Stergios Kechagias, Peter Osmark, Karin G. Stenkula, Martin E. Winberg, Florentina Negoita, Helena A. Jones, Cecilia Holm, Sara Larsson
Publikováno v:
Journal of Cellular Biochemistry. 120:343-356
The mechanism of how patatin-like phospholipase domain-containing protein 3 (PNPLA3) variant M148 is associated with increased risk of development of hepatic steatosis is still debated. Here, we propose a novel role of PNPLA3 as a key player during a
Autor:
Emilia Heimann, Helena A Jones, Svante Resjö, Vincent C Manganiello, Lena Stenson, Eva Degerman
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14191 (2010)
As shown by transgenic mouse models and by using phosphodiesterase 3 (PDE3) inhibitors, PDE3B has an important role in the regulation of insulin secretion in pancreatic β-cells. However, very little is known about the regulation of the enzyme. Here,
Externí odkaz:
https://doaj.org/article/8cc7946781f34417b2248ac3b121c812
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Perilipin 1 is a lipid droplet coating protein known to regulate lipid metabolism in adipocytes by serving as a physical barrier as well as a recruitment site for lipases to the lipid droplet. Phosphorylation of perilipin 1 by protein kinase A rapidl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aec874bf0384cccb02be7a739ddd70
https://doi.org/10.1038/s41598-017-15059-4
https://doi.org/10.1038/s41598-017-15059-4
Publikováno v:
Cellular Signalling. 28:204-213
Parathyroid hormone (PTH) is secreted from the parathyroid glands in response to low plasma calcium levels. Besides its classical actions on bone and kidney, PTH may have other important effects, including metabolic effects, as suggested for instance
Autor:
Jitka Petrlova, Ewa Krupinska, Joan Domingo-Espín, Dorota Kotowska, Helena A. Jones, Catarina Rippe, Jonathan Dalla-Riva, Maria Lindahl, Olga Göransson, Christine Berggreen, Karin G. Stenkula, Jens O. Lagerstedt, Sebastian Wasserstrom, Karl Swärd
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 12, Pp 2248-2259 (2015)
ApoA-I, the main protein component of HDL, is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available. Remarkably, high-fat-fe
Autor:
Christian Krintel, Karin G. Stenkula, Tatu J K Haataja, Karin Lindkvist-Petersson, Madelene Palmgren, Malin Hernebring, Sebastian Wasserstrom, Urszula Kosinska-Eriksson, Cecilia Holm, Jesper S. Hansen, Helena A. Jones, Sofia de Maré
Publikováno v:
Metabolism: clinical and experimental. 65(12)
Accumulating evidence suggests that dysregulated glycerol metabolism contributes to the pathophysiology of obesity and type 2 diabetes. Glycerol efflux from adipocytes is regulated by the aquaglyceroporin AQP7, which is translocated upon hormone stim
Publikováno v:
Cellular Signalling. 24:1863-1871
Salt-inducible kinase (SIK) 3 is a virtually unstudied, ubiquitously expressed serine/threonine kinase, belonging to the AMP-activated protein kinase (AMPK)-related family of kinases, all of which are regulated by LKB1 phosphorylation of a threonine