Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Helena, Silva Cascales"'
Autor:
Eike-Benjamin Braune, Yat Long Tsoi, Yee Peng Phoon, Sebastian Landor, Helena Silva Cascales, Daniel Ramsköld, Qiaolin Deng, Arne Lindqvist, Xiaojun Lian, Cecilia Sahlgren, Shao-Bo Jin, Urban Lendahl
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 643-651 (2016)
Notch signaling is an important regulator of stem cell differentiation. All canonical Notch signaling is transmitted through the DNA-binding protein CSL, and hyperactivated Notch signaling is associated with tumor development; thus it may be anticipa
Externí odkaz:
https://doaj.org/article/27589c4550a849429ff87dd9d4307da5
Autor:
Ida Alexandersson, Nahida Arifen, Firoozeh Salehzadeh, Anders Thorell, Carolina E. Hagberg, Jeremie Boucher, Kirsty L. Spalding, Qian Li, Ping Chen, Niels Krämer, Matthew J. Harms, Carole Knibbe, Shuai Lang, Helena Silva Cascales, Eleni Terezaki, Mervi T. Hyvönen, Myriam Aouadi, Maria Kutschke
Publikováno v:
Nature Medicine
Nature Medicine, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
International audience; Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in obesity is due to an increase in both adipocyte progenitor differen
Autor:
Qian, Li, Carolina E, Hagberg, Helena, Silva Cascales, Shuai, Lang, Mervi T, Hyvönen, Firoozeh, Salehzadeh, Ping, Chen, Ida, Alexandersson, Eleni, Terezaki, Matthew J, Harms, Maria, Kutschke, Nahida, Arifen, Niels, Krämer, Myriam, Aouadi, Carole, Knibbe, Jeremie, Boucher, Anders, Thorell, Kirsty L, Spalding
Publikováno v:
Nature medicine. 27(11)
Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in obesity is due to an increase in both adipocyte progenitor differentiation and mature adipo
Autor:
Helena Silva Cascales, Kamila Burdova, Anna Middleton, Vladislav Kuzin, Erik Müllers, Henriette Stoy, Laura Baranello, Libor Macurek, Arne Lindqvist
Publikováno v:
Life Science Alliance
Main mitotic kinases as PLK1 are activated at the S/G2 transition. A change in Cyclin A2 localisation at the S/G2 transition enables activation of PLK1.
Cyclin A2 is a key regulator of the cell cycle, implicated both in DNA replication and mitot
Cyclin A2 is a key regulator of the cell cycle, implicated both in DNA replication and mitot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49891fc726491f197d7a9baa30e80f75
Publikováno v:
Aging Cell
Summary In response to DNA damage, a cell can be forced to permanently exit the cell cycle and become senescent. Senescence provides an early barrier against tumor development by preventing proliferation of cells with damaged DNA. By studying single
Autor:
Karen Akopyan, Erik Müllers, Danielle A.A. Hollman, Elvira Hukasova, Arne Lindqvist, Adrian T. Saurin, Helena Silva Cascales, Geert J. P. L. Kops, René H. Medema, Himjyot Jaiswal
Publikováno v:
Molecular Cell. 53(5):843-853
Summary During the cell cycle, DNA duplication in S phase must occur before a cell divides in mitosis. In the intervening G2 phase, mitotic inducers accumulate, which eventually leads to a switch-like rise in mitotic kinase activity that triggers mit
In response to DNA damage a cell can be forced to permanently exit the cell cycle and become senescent. Senescence provides an early barrier against tumor development by preventing proliferation of cells with damaged DNA. By studying single cells, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60e5f53b801697e8d501142a87e6e84
Publikováno v:
Aging (Albany NY)
Publikováno v:
Cell cycle (Georgetown, Tex.). 13(17)
Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic in
Autor:
Qiaolin Deng, Eike Benjamin Braune, Yee Peng Phoon, Yat Long Tsoi, Xiaojun Lian, Helena Silva Cascales, Urban Lendahl, Cecilia Sahlgren, Daniel Ramsköld, Sebastian K.-J. Landor, Shao Bo Jin, Arne Lindqvist
Publikováno v:
Stem cell reports, 6(5), 643-51. Cell Press
Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 5, Pp 643-651 (2016)
Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 5, Pp 643-651 (2016)
Summary Notch signaling is an important regulator of stem cell differentiation. All canonical Notch signaling is transmitted through the DNA-binding protein CSL, and hyperactivated Notch signaling is associated with tumor development; thus it may be