Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Helena, Karlström"'
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100326- (2024)
Introduction: CADASIL is the most common monogenic small vessel disease and the most common inherited cause of stroke. The disease is caused by mutations in the NOTCH3-gene, which lead to arteriopathy in small vessels and ischemic events, i.e., trans
Externí odkaz:
https://doaj.org/article/9c9cc602e04a48faa10f95ab111672d7
Autor:
Daniel V Oliveira, Kirsten G Coupland, Wenchao Shao, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, Julie W Rutten, Johan Sandin, Henrik Zetterberg, Johan Lundkvist, Saskia AJ Lesnik Oberstein, Urban Lendahl, Helena Karlström
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease; no preventive or curative therapy is available. CADASIL is caused by mut
Externí odkaz:
https://doaj.org/article/68d5b97efac9440abb6b6bcfdeb077ea
Autor:
Daniel V. Oliveira, Julia Svensson, Xueying Zhong, Henrik Biverstål, Gefei Chen, Helena Karlström
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common familial form of stroke, which is caused by mutations located in the epidermal growth factor (EGF)-like repeats of the NOTCH3 gene
Externí odkaz:
https://doaj.org/article/c752efbc3c43496cb2da3ed32b323270
Autor:
Dan Wu, Sailan Wang, Daniel V. Oliveira, Francesca Del Gaudio, Michael Vanlandewijck, Thibaud Lebouvier, Christer Betsholtz, Jian Zhao, ShaoBo Jin, Urban Lendahl, Helena Karlström
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Infantile myofibromatosis (IMF) is a benign tumor form characterized by the development of nonmetastatic tumors in skin, bone, muscle and sometimes viscera. Autosomal-dominant forms of IMF are caused by mutations in the PDGFRB gene, but a family carr
Externí odkaz:
https://doaj.org/article/d7896892823141bd8f49812317493396
Autor:
Daniel V Oliveira, Kirsten G Coupland, Wenchao Shao, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, Julie W Rutten, Johan Sandin, Henrik Zetterberg, Johan Lundkvist, Saskia AJ Lesnik Oberstein, Urban Lendahl, Helena Karlström
Publikováno v:
EMBO Molecular Medicine. WILEY
EMBO Molecular Medicine
EMBO Molecular Medicine
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease; no preventive or curative therapy is available. CADASIL is caused by mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7916532e5e5d16946f42b074f09cee3c
https://hdl.handle.net/1887/3566779
https://hdl.handle.net/1887/3566779
Autor:
Daniel V. Oliveira, Kirsten G. Coupland, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, Julie W. Rutten, Johan Sandin, Johan Lundkvist, Saskia A. J. Lesnik Oberstein, Urban Lendahl, Helena Karlström
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease and no preventive or curative therapy is available. CADASIL is caused by mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33d0f802322c9d1411737e0f930e5576
https://doi.org/10.1101/2022.07.11.499563
https://doi.org/10.1101/2022.07.11.499563
Autor:
Johanna Wanngren, Patricia Lara, Karin Öjemalm, Silvia Maioli, Nasim Moradi, Lu Chen, Lars O. Tjernberg, Johan Lundkvist, IngMarie Nilsson, Helena Karlström
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 393-406 (2014)
The enzyme complex γ-secretase generates amyloid β-peptide (Aβ), a 37–43-residue peptide associated with Alzheimer disease (AD). Mutations in presenilin 1 (PS1), the catalytical subunit of γ-secretase, result in familial AD (FAD). A unifying th
Externí odkaz:
https://doaj.org/article/d575a72492234136bf2c6d4143b2d91f
Autor:
Katrine Dahl Bjørnholm, Francesca Del Gaudio, Hao Li, Weihan Li, Elisa Vazquez-Liebanas, Maarja Andaloussi Mäe, Urban Lendahl, Christer Betsholtz, Per Nilsson, Helena Karlström, Michael Vanlandewijck
Publikováno v:
Cell Rep Methods
Studying disease-related changes in the brain vasculature is warranted due to its crucial role in supplying oxygen and nutrients and removing waste and due to the anticipated vascular dysfunction in brain diseases. To this end, we have developed a pr
Autor:
Daniel V, Oliveira, Julia, Svensson, Xueying, Zhong, Henrik, Biverstål, Gefei, Chen, Helena, Karlström
Publikováno v:
Frontiers in molecular biosciences. 9
CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common familial form of stroke, which is caused by mutations located in the epidermal growth factor (EGF)-like repeats of the
Autor:
K. D. Bjornholm, Helena Karlström, Michael Vanlandewijck, Per Nilsson, F. Del Gaudio, Christer Betsholtz, Urban Lendahl
The blood-brain barrier (BBB) is central to separate blood from the extracellular fluids of the brain. To understand disease-related changes in the BBB is pivotal and such changes can increasingly be studied by single-cell RNA sequencing (scRNAseq),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d73d6d8da82e92310ef7abd2be2e20c0
https://doi.org/10.1101/2021.08.31.458349
https://doi.org/10.1101/2021.08.31.458349