Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Helena, Cucak"'
Autor:
Samuel Alsén, Jakob Cervin, Yaxiong Deng, Louis Szeponik, Ulf Alexander Wenzel, Joakim Karlsson, Helena Cucak, Megan Livingston, David Bryder, Qianjin Lu, Bengt Johansson-Lindbom, Ulf Yrlid
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells interact with T follicular helper (Tfh) cells in germinal centers (GCs) to generate high-affinity antibodies. Much less is known about how cognate T–B-cell interactions influence Th cells that enter circulation and peripheral tissues. There
Externí odkaz:
https://doaj.org/article/4d799bf2f9044fdbb729db3bcd5cb042
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
The cytokine interleukin-1β (IL-1β) is known to stimulate proinflammatory immune responses and impair β-cell function and viability, all critical events in the pathogenesis of type 1 diabetes (T1D). Here we evaluate the effect of SER140, a small p
Externí odkaz:
https://doaj.org/article/e73bf756afa04c55b061a33bcfdaeded
Autor:
Samuel, Alsén, Jakob, Cervin, Yaxiong, Deng, Louis, Szeponik, Ulf Alexander, Wenzel, Joakim, Karlsson, Helena, Cucak, Megan, Livingston, David, Bryder, Qianjin, Lu, Bengt, Johansson-Lindbom, Ulf, Yrlid
Publikováno v:
Frontiers in immunology. 13
B cells interact with T follicular helper (Tfh) cells in germinal centers (GCs) to generate high-affinity antibodies. Much less is known about how cognate T-B-cell interactions influence Th cells that enter circulation and peripheral tissues. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70f3dd333cccfce008f3769906a8a691
https://pubmed.ncbi.nlm.nih.gov/35355990
https://pubmed.ncbi.nlm.nih.gov/35355990
Autor:
Christopher Mayer, Regine Bergholdt, Helena Cucak, Bidda Charlotte Rolin, Anette Sams, Alexander Rosendahl
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131306 (2015)
Low grade inflammation is present in pre-clinical and human type 2 diabetes. In this process, several cytokines like IL-1β and inflammatory cells like macrophages are activated and demonstrated to participate to the disease initiation and progressio
Externí odkaz:
https://doaj.org/article/cc364390f9244d0a81bd2fa5b43a56a7
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107140 (2014)
Low-grade inflammation, characterized by increased pro-inflammatory cytokine levels, is present in patients with obesity-linked insulin resistance, hyperglycemia and hyperlipidemia and considered to play a leading role to progression into type 2 diab
Externí odkaz:
https://doaj.org/article/67101a05d48c47e3bd66a50e11bcadf0
Autor:
Helena Cucak, Christopher Mayer, Morten Tonnesen, Lise Høj Thomsen, Lars Groth Grunnet, Alexander Rosendahl
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90685 (2014)
Type 2 diabetes (T2D) is evolving into a global disease and patients have a systemic low-grade inflammation, yet the role of this inflammation is still not established. One plausible mechanism is enhanced expression and activity of the innate immune
Externí odkaz:
https://doaj.org/article/b206f41387504f27bfaca896d4e57310
Autor:
Samuel Alsén, Megan Livingston, Tobias Gustafsson-Hedberg, Bengt Johansson-Lindbom, Ulf Yrlid, Madelene W. Dahlgren, Helena Cucak
Publikováno v:
The Journal of Immunology. 194:5187-5199
Development of long-lived humoral immunity is dependent on CXCR5-expressing T follicular helper (Tfh) cells, which develop concomitantly to effector Th cells that support cellular immunity. Conventional dendritic cells (cDCs) are critical APCs for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfa444af8e21f20628aa6b08cbd26a0
https://doi.org/10.4049/jimmunol.1401938
https://doi.org/10.4049/jimmunol.1401938
Publikováno v:
International Immunopharmacology. 25(1):30-42
Diabetic nephropathy (DN) is a serious complication of longstanding diabetes affecting up to 30% of all diabetes patients and is the main cause of end-stage kidney disease globally. Current standard treatment e.g. ACE-inhibitors like enalapril merely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9c7a2b23cdd4522de55e8526db958e
Publikováno v:
Journal of Biological Chemistry. 288:28398-28408
Transferrin internalization via clathrin-mediated endocytosis and subsequent recycling after iron delivery has been extensively studied. Here we demonstrate a previously unrecognized parameter regulating this recycling, the binding of galectin-3 to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc589d8597ab243e8aab70aeb1869d97
https://doi.org/10.1074/jbc.m113.487793
https://doi.org/10.1074/jbc.m113.487793
Autor:
Tanja X. Pedersen, Helena Cucak, Alexander Rosendahl, Salka E. Rasmussen, Christina K. Mogensen, Lars Bo Nielsen, Line S. Bisgaard
Publikováno v:
Scientific Reports
Bisgaard, L S, Mogensen, C K, Rosendahl, A, Cucak, H, Nielsen, L B, Rasmussen, S E & Pedersen, T X 2016, ' Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression : implications for atherosclerosis research ', Scientific Reports, vol. 6, 35234 . https://doi.org/10.1038/srep35234
Bisgaard, L S, Mogensen, C K, Rosendahl, A, Cucak, H, Nielsen, L B, Rasmussen, S E & Pedersen, T X 2016, ' Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression : implications for atherosclerosis research ', Scientific Reports, vol. 6, 35234 . https://doi.org/10.1038/srep35234
Macrophages are heterogeneous and can polarize into specific subsets, e.g. pro-inflammatory M1-like and re-modelling M2-like macrophages. To determine if peritoneal macrophages (PEMs) or bone marrow derived macrophages (BMDMs) resembled aortic macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dddc66b92adae39020244ec0a56d127
https://doi.org/10.1038/srep35234
https://doi.org/10.1038/srep35234