Výsledky vyhledávání - "Helen Zgurskaya"

Synthesis and Testing of Analogs of the Tuberculosis Drug SQ109 Against Bacteria and Protozoa: Identification of Lead Compounds Against Mycobacterium abscessus and Malaria

SQ109 is a tuberculosis drug candidate that has high potency against Mycobacterium tuberculosis and is thought to function at least in part by blocking cell wall biosynthesis by inhibiting the MmpL3 transporter. It also has activity against bacteria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9134204720e18151a5bb4fe61122aae7
https://doi.org/10.26434/chemrxiv-2022-xm94p

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Epistatic Effects of the Protease/Chaperone HflB on Some Damaged Forms of the Escherichia coli Ammonium Channel AmtB

Autor: William Inwood, Helen Zgurskaya, Sydney Kustu, Lusine Demirkhanyan, Jason A. Hall, Kwang-Seo Kim, David E. Wemmer

Publikováno v: Genetics. 183:1327-1340

The Escherichia coli ammonium channel AmtB is a trimer in which each monomer carries a pore for substrate conduction and a cytoplasmic C-terminal extension of ∼25 residues. Deletion of the entire extension leaves the protein with intermediate activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356ed7ce2d1d704a7f0e00da84161ebf
https://doi.org/10.1534/genetics.109.103747

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Rethinking antibiotics

Autor: Helen Zgurskaya

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, Vol 6 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0344a8230c1d6a90517b7cb80f32eac
http://europepmc.org/articles/PMC4338803

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Multidrug Efflux Pumps

Autor: Helen Zgurskaya, Olga Lomovskaya, Kim Lewis, Keith Bostian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14aee7bfdcf0b04e063aa86397654fdd
https://doi.org/10.1201/9781420008753.ch4

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