Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helen Yvette Barnett"'
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 18
Issue 1
International Journal of Environmental Research and Public Health, Vol 18, Iss 345, p 345 (2021)
Volume 18
Issue 1
International Journal of Environmental Research and Public Health, Vol 18, Iss 345, p 345 (2021)
There is growing interest in Phase I dose-finding studies studying several doses of more than one agent simultaneously. A number of combination dose-finding designs were recently proposed to guide escalation/de-escalation decisions during the trials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0791bcf25b7286bfbc84fc2cff2cd17
https://pubmed.ncbi.nlm.nih.gov/33466469
https://pubmed.ncbi.nlm.nih.gov/33466469
Pharmacokinetic (PK) studies are conducted to learn about the absorption, distribution, metabolism, and excretion processes of an externally administered compound by measuring its concentration in bodily tissue at a number of time points after admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6c8f7b94abe88e71ca358df632ad1a
Publikováno v:
Statistics in Medicine. 36:4301-4315
Pharmacokinetic studies aim to study how a compound is absorbed, distributed, metabolised, and excreted. The concentration of the compound in the blood or plasma is measured at different time points after administration and pharmacokinetic parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c63b4453bd6248f0b22ba8fc4001f2
https://doi.org/10.1002/sim.7436
https://doi.org/10.1002/sim.7436
In traditional toxicology trials, pharmacokinetics (PK) is investigated in the satellite group of animals, and the pharmacodynamics (PD) is investigated in the study group of animals. The new blood sampling method of microsampling opens up the opport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5681187db0f8a59684ee6c6db6f14ab7
Autor:
Barnett, Helen Yvette1 (AUTHOR) helenyvetteb@gmail.com, Villar, Sofía S.1 (AUTHOR), Geys, Helena2 (AUTHOR), Jaki, Thomas1,3 (AUTHOR)
Publikováno v:
Biometrics. Mar2023, Vol. 79 Issue 1, p86-97. 12p.
Autor:
Barnett, Helen Yvette1 (AUTHOR), Geys, Helena2 (AUTHOR), Jacobs, Tom2 (AUTHOR), Jaki, Thomas1 (AUTHOR)
Publikováno v:
Statistics in Biopharmaceutical Research. Jan-Mar2021, Vol. 13 Issue 1, p59-70. 12p.
Publikováno v:
Statistics in Biopharmaceutical Research. Oct-Dec2018, Vol. 10 Issue 4, p255-263. 9p.