Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Helen Yarwood"'
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
MOV file 2346K, Video showing dynamic flow adhesion assays of ZR75.1 shNTC and shST6 cells on a HUVEC monolayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54634eae540fd48fc7761c33e8d18f33
https://doi.org/10.1158/2159-8290.22530449
https://doi.org/10.1158/2159-8290.22530449
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
PDF file 149K, In vivo validation of 3 hits identified in the screen (Mre11a, Fen1, Wwc1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5b4a288982247c053d4b16c2f81732
https://doi.org/10.1158/2159-8290.22530473
https://doi.org/10.1158/2159-8290.22530473
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
PDF file 174K, Additional characterization of the 4T1-Luc cells in lung retention assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39f0f6701d47a72c01def649017feda
https://doi.org/10.1158/2159-8290.22530464
https://doi.org/10.1158/2159-8290.22530464
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
PDF file 95K, Data demonstrating that siRNA mediated downregulation of ST6GalNAc2 expression in human and mouse cell lines promotes tumor cell aggregation in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec111f22fa96aa21663a145e1b61674
https://doi.org/10.1158/2159-8290.22530455.v1
https://doi.org/10.1158/2159-8290.22530455.v1
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
MOV file 2886K, Video showing dynamic flow adhesion assays of ZR75.1 shNTC and shST6 cells on a HUVEC monolayer in the presence of the galectin-3 inhibitor GCS-100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deacb3dfa67ac25f91bcf91255c2412b
https://doi.org/10.1158/2159-8290.22530446
https://doi.org/10.1158/2159-8290.22530446
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
PDF file 299K, Additional characterization of human breast cancer cell lines; immunofluorescence analysis and lung retention assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ee640c0258ae8073be806269f807ff
https://doi.org/10.1158/2159-8290.22530458.v1
https://doi.org/10.1158/2159-8290.22530458.v1
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
PDF file 60K, Characterization of the MDA-MB-231 cells stably expressing vector or mouse ST6GalNAc2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da853d58f59ef056f0529271b94d94e
https://doi.org/10.1158/2159-8290.22530467.v1
https://doi.org/10.1158/2159-8290.22530467.v1
Autor:
Clare M. Isacke, Alan Ashworth, Christopher J. Lord, Helen Yarwood, Anne Dell, Stuart M. Haslam, Marketa Zvelebil, Nick Orr, Qiong Gao, Costas Mitsopoulos, Kerry Fenwick, David Sims, Mariam Jamal-Hanjani, Antony Fearns, Aristotelis Antonopoulos, Damian A. Johnson, Aleksandar Ivetic, Antoinette van Weverwijk, Marjan Iravani, Nirupa Murugaesu
PDF file 107K, Inventory of supplementary material. Supplementary Table S1 listing primers and siRNAs. Legends for Supplementary Fig. S1 - S7 Legends for Supplementary Movies S1 and S2 Supplementary Figures S1 - S6 legends Supplementary Movies S1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fba01ad96e140398e33d7cfa661ef8d
https://doi.org/10.1158/2159-8290.22530452.v1
https://doi.org/10.1158/2159-8290.22530452.v1
Autor:
Qiong Gao, Stuart M. Haslam, Helen Yarwood, Mariam Jamal-Hanjani, Aristotelis Antonopoulos, Damian A. Johnson, Marjan Iravani, Kerry Fenwick, David Sims, Costas Mitsopoulos, Nick Orr, Alan Ashworth, Nirupa Murugaesu, Clare M. Isacke, Marketa Zvelebil, Christopher J. Lord, Antoinette van Weverwijk, Antony Fearns, Aleksandar Ivetic, Anne Dell
Publikováno v:
Cancer Discovery. 4:304-317
To interrogate the complex mechanisms involved in the later stages of cancer metastasis, we designed a functional in vivo RNA interference (RNAi) screen combined with next-generation sequencing. Using this approach, we identified the sialyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2f1523106820781f98337f6b13b899
https://doi.org/10.1158/2159-8290.cd-13-0287
https://doi.org/10.1158/2159-8290.cd-13-0287
Publikováno v:
Journal of Cell Science. 122:4042-4048
The molecular interactions leading to organised, controlled extracellular matrix degradation are of central importance during growth, development and tissue repair, and when deregulated contribute to disease processes including cancer cell invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c3c854514f8dcb02cb105760eea944
https://doi.org/10.1242/jcs.044305
https://doi.org/10.1242/jcs.044305