Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Helen Y. Chen"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5256-5263 (2022)
Over the past decade, our understanding of human diseases has rapidly grown from the rise of single-cell spatial biology. While conventional tissue imaging has focused on visualizing morphological features, the development of multiplex tissue imaging
Externí odkaz:
https://doaj.org/article/da86f0d8ed5e4b20be84d245ed0e4194
Autor:
Ramkumar Aishworiya, Shirong Cai, Helen Y. Chen, Desiree Y. Phua, Birit F. P. Broekman, Lourdes Mary Daniel, Yap Seng Chong, Lynette P. Shek, Fabian Yap, Shiao-Yng Chan, Michael J. Meaney, Evelyn C. Law
Publikováno v:
BMC Pediatrics, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Although infant media exposure has received attention for its implications on child development, upstream risk factors contributing to media exposure have rarely been explored. The study aim was to examine the relationship between
Externí odkaz:
https://doaj.org/article/2b1400fea63846e08935a3f988c1fb66
Autor:
Shengxiao Vincent Feng, Willem van den Boom, Maria De Iorio, Gladi J. Thng, Jerry K. Y. Chan, Helen Y. Chen, Kok Hian Tan, Michelle Z. L. Kee
Publikováno v:
Journal of Applied Statistics. :1-18
Maternal depression and anxiety through pregnancy have lasting societal impacts. It is thus crucial to understand the trajectories of its progression from preconception to postnatal period, and the risk factors associated with it. Within the Bayesian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafecfc2aedca281c85e727c18c8ff24
https://doi.org/10.1080/02664763.2022.2154329
https://doi.org/10.1080/02664763.2022.2154329
Publikováno v:
JAWRA Journal of the American Water Resources Association. 57:109-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b21c667aef378a505f5dcabc8e2ba90
https://doi.org/10.1111/1752-1688.12894
https://doi.org/10.1111/1752-1688.12894
Publikováno v:
International journal of psychiatry in medicine.
Objective Balint groups provide a safe space for clinicians to discuss difficult cases, with the aim of deepening the clinician-patient relationship and providing space for self-introspection and personal development. During this COVID-19 period, men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd62769b817fedefc920a578306250d7
https://pubmed.ncbi.nlm.nih.gov/35499173
https://pubmed.ncbi.nlm.nih.gov/35499173
Publikováno v:
Annals of the Academy of Medicine, Singapore. 45:466-470
Postnatal depression is a major public health problem with clearly established adverse effects in child outcomes. This study examines the 4-year outcomes of a screening and early intervention programme, in relation to improvement in symptoms, functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c8328ef308128d704a5c82dbe8cd40
https://doi.org/10.47102/annals-acadmedsg.v45n10p466
https://doi.org/10.47102/annals-acadmedsg.v45n10p466
Publikováno v:
Journal of Biological Chemistry. 281:7825-7833
Sialic acids are sometimes 9-O-acetylated in a developmentally regulated and cell-type-specific manner. Cells naturally expressing the disialoganglioside GD3 often O-acetylate the terminal sialic acid residue, giving 9-O-acetyl-GD3 (9AcGD3), a marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d049484c8b1ba0223949b93379ce42a7
https://doi.org/10.1074/jbc.m512379200
https://doi.org/10.1074/jbc.m512379200
Publikováno v:
Journal of Biological Chemistry. 278:7942-7948
9-O-Acetylation is a common sialic acid modification, expressed in a developmentally regulated and tissue/cell type-specific manner. The relevant 9-O-acetyltransferase(s) have not been isolated or cloned; nor have mechanisms for their regulation been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f16a992f1cd027e63190a38bfd31cb
https://doi.org/10.1074/jbc.m210565200
https://doi.org/10.1074/jbc.m210565200
Autor:
Helen Y. Chen, Ajit Varki
Publikováno v:
Journal of Experimental Medicine. 196:1529-1533
Glycosphingolipids (GSLs) are amphipathic molecules with a polar glycan chain as a head group and a hydrophobic sphingosine-containing ceramide tail, which is typically embedded in the outer leaflet of the plasma membrane ([1][1]). GSLs are no longer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d9d4688feafc8d6931d88351fb7e7d
https://doi.org/10.1084/jem.20021915
https://doi.org/10.1084/jem.20021915
Autor:
Walter G. Smith, Suzanne H Kim, Doreen Villani-Price, Matthew W Mahoney, Nayereh S Ghoreishi-Haack, Helen Y. Chen, Thomas D. Penning, Stella Siu-Tzyy Yu, James W. Malecha, Leslie J Askonas, Chi-Dean Liang, Elizabeth I Harding, E.Yvonne Pyla, Maureen K Highkin, James K. Gierse, Julie M Miyashiro, Mark A Russell, James F Kachur, Chen Barbara B
Publikováno v:
Journal of Medicinal Chemistry. 45:3482-3490
Leukotriene B(4) (LTB(4)) is a potent, proinflammatory mediator involved in the pathogenesis of a number of diseases including inflammatory bowel disease, psoriasis, rheumatoid arthritis, and asthma. The enzyme LTA(4) hydrolase represents an attracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49aaaeb42023ad7fd78de02ecc724a97
https://doi.org/10.1021/jm0200916
https://doi.org/10.1021/jm0200916